InAADR

Drug Information

Drug Name: Tipranavir (174484-41-4)
PubChem ID: 54682461
SMILES: CCC[C@]1(CC(=C(C(=O)O1)[C@H](CC)C2=CC(=CC=C2)NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)O)CCC4=CC=CC=C4
InchiKey: SUJUHGSWHZTSEU-FYBSXPHGSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 602.675
LogP: 7.3255
Ring Count: 3
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 105.59

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Rigidity MetaADEDB
Abnormal Lfts MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accidental Death MetaADEDB
Acquired Immune Deficiency Syndrome MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Sinusitis MetaADEDB
Adenocarcinoma MetaADEDB
Administration Site Pain MetaADEDB
Aids Dementia Complex MetaADEDB
Alanine Aminotransferase Increased SIDER
Amentia MetaADEDB
Amylase Increased SIDER
Anaemia ADReCS
Anaemia Of Chronic Disease MetaADEDB
Anal Abscess MetaADEDB
Anal Atresia MetaADEDB
Anal Fissure MetaADEDB
Anal Haemorrhage MetaADEDB
Anogenital Warts MetaADEDB
Anorectal Agenesis MetaADEDB
Anorexia ADReCS
Anti-Hbc Antibody MetaADEDB
Anti-Neutrophil Cytoplasmic Antibody Positive Vasculitis MetaADEDB
Anticonvulsant Drug Level Decreased MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apoplexy MetaADEDB
Appendicitis Perforated MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased SIDER
Aspergillosis MetaADEDB
Asthenia ADReCS
Asystole MetaADEDB
Atrial Tachycardia MetaADEDB
Autoimmune Disorder PROTECT
Bacterial Toxaemia MetaADEDB
Basedow Disease PROTECT
Bicytopenia MetaADEDB
Bile Duct Obstruction MetaADEDB
Bilirubin Conjugated Abnormal MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Birth Defect MetaADEDB
Bladder Agenesis MetaADEDB
Blood Amylase Increased ADReCS
Blood Bilirubin Increased ADReCS
Blood Bilirubin Unconjugated Increased MetaADEDB
Blood Cholesterol Increased PROTECT
Blood Creatine Phosphokinase Increased PROTECT
Blood Electrolytes Abnormal MetaADEDB
Blood Hiv Rna MetaADEDB
Blood Iron Decreased MetaADEDB
Blood Iron Increased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Triglycerides Increased ADReCS
Body Fat Disorder PROTECT
Body Temperature MetaADEDB
Body Temperature Increased ADReCS
Bone Disorder ADReCS
Brain Abscess MetaADEDB
Brain Herniation MetaADEDB
Brain Mass MetaADEDB
Brain Stem Infarction MetaADEDB
Breast Abscess MetaADEDB
Breast Enlargement PROTECT
Bronchiolitis MetaADEDB
Bronchitis ADReCS
Bruise MetaADEDB
Bulbar Palsy MetaADEDB
Burn Oesophageal MetaADEDB
Cachectic MetaADEDB
Cachexia ADReCS
Candidiasis ADReCS
Cardiac Failure MetaADEDB
Cardiac Tamponade MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Carotid Artery Stenosis MetaADEDB
Catheter Related Infection MetaADEDB
Caudal Regression Syndrome MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cervical Spinal Stenosis MetaADEDB
Chills ADReCS
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Chorioretinitis ADReCS
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Obstructive Airways Disease Exacerbated MetaADEDB
Cirrhosis MetaADEDB
Cleft Palate ADReCS
Cloacal Exstrophy MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Colitis MetaADEDB
Clostridium Difficile Toxin Test Positive MetaADEDB
Cmv Infection MetaADEDB
Coagulation Factor Decreased MetaADEDB
Coagulation Time Prolonged MetaADEDB
Cognitive Disorder MetaADEDB
Coma MetaADEDB
Completed Suicide MetaADEDB
Computerised Tomogram MetaADEDB
Congenital Aplastic Anaemia MetaADEDB
Congenital Genital Malformation MetaADEDB
Congenital Musculoskeletal Anomaly MetaADEDB
Connective Tissue Disorder SIDER
Constipation ADReCS
Convulsion MetaADEDB
Coombs Direct Test Positive MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Cryptococcosis MetaADEDB
Cryptogenic Organising Pneumonia MetaADEDB
Cyst ADReCS
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Cytomegalovirus Oesophagitis MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Deglutition Disorder MetaADEDB
Dehydration ADReCS
Delusion MetaADEDB
Demyelination MetaADEDB
Dermatitis ADReCS
Diabetes Mellitus ADReCS
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Eruption PROTECT
Drug Ineffective MetaADEDB
Drug Resistance MetaADEDB
Dysaesthesia MetaADEDB
Dyspepsia ADReCS
Dyspnoea ADReCS
Eaton-Lambert Syndrome MetaADEDB
Electrocardiogram Pr Prolongation MetaADEDB
Embolism Pulmonary MetaADEDB
Encephalitis MetaADEDB
Encephalitis Viral MetaADEDB
Encephalopathy MetaADEDB
Encephalopathy Hypertensive MetaADEDB
Enlarged Spleen MetaADEDB
Epididymitis MetaADEDB
Epilepsy MetaADEDB
Epistaxis ADReCS
Erythema PROTECT
Escherichia Bacteraemia MetaADEDB
Escherichia Infection MetaADEDB
Esophageal Ulcer MetaADEDB
Excessive Sleepiness MetaADEDB
Exomphalos MetaADEDB
Facial Wasting ADReCS
Fat Redistribution PROTECT
Fatigue ADReCS
Feeling Abnormal ADReCS
Flank Pain MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Gamma-Glutamyltransferase Increased ADReCS
Gastric Hyperplasia MetaADEDB
Gastroenteritis ADReCS
Gastroenteritis Cryptosporidial MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Disorder Congenital MetaADEDB
Gastrointestinal Malformation MetaADEDB
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
General Physical Health Deterioration MetaADEDB
Genitalia External Ambiguous MetaADEDB
Globulins Increased MetaADEDB
Granuloma MetaADEDB
Haemarthrosis ADReCS
Haematoma MetaADEDB
Haemolysis MetaADEDB
Haemorrhage Intracranial ADReCS
Haemorrhagic Diathesis PROTECT
Haptoglobin Decreased MetaADEDB
Headache ADReCS
Hemianopia MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Steatosis ADReCS
Hepatitis PROTECT
Hepatitis B MetaADEDB
Hepatitis B Surface Antigen Positive MetaADEDB
Hepatitis C Positive MetaADEDB
Hepatitis C Virus Test MetaADEDB
Hepatitis Toxic PROTECT
Hepatobiliary Disease SIDER
Hepatocellular Injury MetaADEDB
Hepatojugular Reflux MetaADEDB
Herpes Nos SIDER
Herpes Simplex ADReCS
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hip Fracture MetaADEDB
Hiv Disease MetaADEDB
Hiv Infection ADReCS
Hodgkin Disease MetaADEDB
Hydrocephalus MetaADEDB
Hyperamylasaemia SIDER
Hyperbilirubinaemia ADReCS
Hypercholesterolaemia ADReCS
Hyperglycaemia ADReCS
Hyperlipidaemia ADReCS
Hypersensitivity ADReCS
Hypertensive Hydrocephalus MetaADEDB
Hypertriglyceridaemia ADReCS
Hypophosphataemia MetaADEDB
Hypovolaemia MetaADEDB
Ild MetaADEDB
Ill-Defined Disorder ADReCS
Immune Reconstitution Inflammatory Syndrome PROTECT
Immune System Disorder SIDER
Immunodeficiency MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Viral MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Influenza Like Illness ADReCS
Injection Site Dermatitis MetaADEDB
Injection Site Mass MetaADEDB
Insomnia ADReCS
Insufficiency Renal SIDER
Insulin Resistance PROTECT
Interstitial Nephritis MetaADEDB
Intestinal Perforation MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intracranial Aneurysm MetaADEDB
Intracranial Haematoma MetaADEDB
Intraventricular Haemorrhage MetaADEDB
Jaundice ADReCS
Kaposi Sarcoma MetaADEDB
Klebsiella Sepsis MetaADEDB
Leucopenia MetaADEDB
Leukoencephalopathy ADReCS
Lipase Increased ADReCS
Lipoatrophy ADReCS
Lipodystrophy ADReCS
Lipodystrophy Acquired ADReCS
Lipohypertrophy ADReCS
Liver Abscess MetaADEDB
Liver Function Test Abnormal ADReCS
Liver Transplant MetaADEDB
Loss Of Weight MetaADEDB
Lower Limb Fracture MetaADEDB
Lung Edema MetaADEDB
Lung Infection Pseudomonal MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Lymphadenopathy ADReCS
Lymphocytosis MetaADEDB
Lymphoma ADReCS
Malaise ADReCS
Malignant Soft Tissue Neoplasm MetaADEDB
Malnourished MetaADEDB
Mastoiditis MetaADEDB
Meconium Stain MetaADEDB
Mediastinal Disorder SIDER
Megacolon MetaADEDB
Meningeal Disorder MetaADEDB
Meningocele MetaADEDB
Mental Disorder SIDER
Mental Status Changes MetaADEDB
Microlithiasis MetaADEDB
Migraine With Aura MetaADEDB
Miosis MetaADEDB
Mitochondrial Toxicity ADReCS
Monoparesis MetaADEDB
Mucosal Haemorrhage MetaADEDB
Mucous Stools MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple-Drug Resistance MetaADEDB
Muscle Haemorrhage ADReCS
Muscle Spasms ADReCS
Musculoskeletal Deformity MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Mycobacterial Infection MetaADEDB
Myositis PROTECT
Nausea ADReCS
Necrotising Colitis MetaADEDB
Neglect Of Personal Appearance MetaADEDB
Neonatal Aspiration MetaADEDB
Neoplasm ADReCS
Nephritic Syndrome MetaADEDB
Nephrotic Syndrome MetaADEDB
Nervous System Disorder SIDER
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
No Adverse Drug Effect MetaADEDB
Normal Pressure Hydrocephalus MetaADEDB
Oesophageal Adenocarcinoma MetaADEDB
Oesophageal Candidiasis ADReCS
Oesophageal Disorder ADReCS
Oesophageal Infection MetaADEDB
Oral Discomfort MetaADEDB
Osteomyelitis MetaADEDB
Osteomyelitis Bacterial MetaADEDB
Osteonecrosis PROTECT
Overdose MetaADEDB
Pain ADReCS
Pancreatitis ADReCS
Perianal Abscess MetaADEDB
Peritoneal Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pneumocystis Carinii Pneumonia SIDER
Pneumocystis Jiroveci Pneumonia ADReCS
Pneumonia ADReCS
Polyp ADReCS
Portal Hypertension MetaADEDB
Post Lumbar Puncture Syndrome MetaADEDB
Post Procedural Haematoma MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Infection MetaADEDB
Premature Baby MetaADEDB
Premature Labour MetaADEDB
Progressive Multifocal Leukoencephalopathy ADReCS
Prostatic Disorder MetaADEDB
Prostatitis MetaADEDB
Protein Total Increased MetaADEDB
Prothrombin Level Increased ADReCS
Pruritus ADReCS
Pseudomonal Sepsis MetaADEDB
Pseudomonas Infection MetaADEDB
Psoriasis MetaADEDB
Pulmonary Hypertension MetaADEDB
Pyrexia PROTECT
Rash ADReCS
Rash Macular PROTECT
Rash Maculo-Papular PROTECT
Rash Papular PROTECT
Rash Pruritic PROTECT
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Tubular Acidosis MetaADEDB
Respiratory Tract Infection Bacterial MetaADEDB
Retching PROTECT
Reversible Ischaemic Neurological Deficit MetaADEDB
Rhabdomyolysis PROTECT
Rhonchi MetaADEDB
Rigors SIDER
Rupture Of Spleen MetaADEDB
Septic Shock MetaADEDB
Serositis MetaADEDB
Shock Haemorrhagic MetaADEDB
Sickness SIDER
Sigmoiditis MetaADEDB
Sinusitis MetaADEDB
Sleep Disorder ADReCS
Somnolence ADReCS
Spine Malformation MetaADEDB
Splenic Abscess MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Subcutaneous Abscess MetaADEDB
Subcutaneous Haematoma MetaADEDB
Subcutaneous Nodule MetaADEDB
Tethered Cord Syndrome MetaADEDB
Therapy Non-Responder MetaADEDB
Thrombocytopenia ADReCS
Thrombotic Microangiopathy MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Toxicologic Test Abnormal MetaADEDB
Toxoplasmosis MetaADEDB
Transaminases Increased MetaADEDB
Treatment Noncompliance MetaADEDB
Umbilical Cord Abnormality MetaADEDB
Unevaluable Event MetaADEDB
Ureaplasma Infection MetaADEDB
Urethral Disorder SIDER
Urinary Tract Disorder SIDER
Urine Amphetamine Positive MetaADEDB
Urticaria PROTECT
Varicella ADReCS
Varicella Zoster SIDER
Viral Load MetaADEDB
Viral Load Decreased MetaADEDB
Viral Mutation Identified MetaADEDB
Vocal Cord Disorder MetaADEDB
Vomiting ADReCS
Wasting SIDER
Weight Decreased ADReCS
Wheelchair User MetaADEDB
White Blood Cell Count Decreased SIDER
White Blood Cell Count Low SIDER

InAADR: Drug-Protein-ADRs database