InAADR

Drug Information

Drug Name: Riluzole (1744-22-5)
PubChem ID: 5070
SMILES: C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
InchiKey: FTALBRSUTCGOEG-UHFFFAOYSA-N
Therapeutic Category: Anticonvulsants, Central Nervous System Agents, Excitatory Amino Acid Agents, Excitatory Amino Acid Antagonists, Neuroprotective Agents, Neurotransmitter Agents, Protective Agents

Computed Drug Properties

Molecular Weight (dalton): 234.202
LogP: 2.7771
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 48.14

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abnormal Dreams ADReCS
Abnormal Gait ADReCS
Abscess ADReCS
Accidental Injury ADReCS
Acidosis ADReCS
Acrodynia ADReCS
Acute Coronary Syndrome ADReCS
Acute Leukaemia MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenopathy MetaADEDB
Adverse Reaction ADReCS
Adynamic Ileus MetaADEDB
Affect Lability ADReCS
Afib MetaADEDB
Ageusia ADReCS
Agitation ADReCS
Agranulocytosis ADReCS
Agraphia MetaADEDB
Alanine Aminotransferase Increased ADReCS
Allergic Alveolitis MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Vasculitis MetaADEDB
Alopecia ADReCS
Als MetaADEDB
Altered State Of Consciousness ADReCS
Alveolitis ADReCS
Alveolitis Allergic ADReCS
Amblyopia ADReCS
Amenorrhoea ADReCS
Amnesia ADReCS
Amyotrophic Lateral Sclerosis MetaADEDB
Amyotrophy MetaADEDB
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anorectal Discomfort ADReCS
Anorexia ADReCS
Anuria ADReCS
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apathy ADReCS
Aplastic Anaemia ADReCS
Apnea MetaADEDB
Apnoea ADReCS
Aptyalism MetaADEDB
Arterial Occlusion SIDER
Arterial Occlusive Disease ADReCS
Arteriosclerosis MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Arthropathy ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia MetaADEDB
Aspiration ADReCS
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Ataxia ADReCS
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Back Pain ADReCS
Bacteria Stool Identified MetaADEDB
Biliary Colic ADReCS
Bilirubin Abnormal ADReCS
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Blepharitis ADReCS
Blindness ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Bicarbonate MetaADEDB
Blood Bilirubin Abnormal ADReCS
Blood Creatinine Increased ADReCS
Blood Fibrinogen Increased MetaADEDB
Blood Immunoglobulin A Increased MetaADEDB
Blood Immunoglobulin E MetaADEDB
Blood Immunoglobulin G Increased MetaADEDB
Blood Lactate Dehydrogenase Increased ADReCS
Blood Ph Increased MetaADEDB
Blood Potassium Decreased ADReCS
Blood Pressure Increased ADReCS
Body Temperature Decreased ADReCS
Body Temperature Increased ADReCS
Bone Neoplasm ADReCS
Bradycardia ADReCS
Bradypnoea MetaADEDB
Breakthrough Pain MetaADEDB
Breast Abscess ADReCS
Breast Disorder SIDER
Breast Pain ADReCS
Bronchial Obstruction MetaADEDB
Bronchitis ADReCS
Bundle Branch Block ADReCS
Calculus Of Kidney SIDER
Candidiasis ADReCS
Carcinoma SIDER
Carcinoma Of Lung SIDER
Cardiac Arrest ADReCS
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardiac Ischemia MetaADEDB
Cardiac Murmur ADReCS
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathy ADReCS
Cartilage Development Disorder MetaADEDB
Cataract ADReCS
Cellulitis ADReCS
Central Nervous System Lesion MetaADEDB
Cerebral Artery Embolism ADReCS
Cerebral Embolism ADReCS
Cerebral Haematoma ADReCS
Cerebral Haemorrhage ADReCS
Cerebral Ischaemia ADReCS
Cervicalgia MetaADEDB
Cheilitis ADReCS
Chest Pain ADReCS
Chills ADReCS
Choking ADReCS
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis ADReCS
Cholestasis ADReCS
Chronic Left Ventricular Failure MetaADEDB
Circumoral Paresthesia ADReCS
Clostridium Difficile Colitis MetaADEDB
Cns Depression Nos SIDER
Coma ADReCS
Completed Suicide ADReCS
Condition Aggravated ADReCS
Confusional State ADReCS
Congenital Anomaly ADReCS
Congenital Central Nervous System Anomaly ADReCS
Congenital Foot Malformation ADReCS
Congestive Cardiomyopathy ADReCS
Connective Tissue Disorder SIDER
Constipation ADReCS
Constrictive Pericarditis MetaADEDB
Convulsion ADReCS
Coombs Direct Test Positive ADReCS
Coordination Abnormal ADReCS
Cor Pulmonale ADReCS
Corneal Ulcer MetaADEDB
Coronary Artery Stenosis MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Creatinine Increased SIDER
Cyanosis ADReCS
Cyst ADReCS
Cytolytic Hepatitis ADReCS
Deafness ADReCS
Death ADReCS
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Deficiency Anaemia ADReCS
Deglutition Disorder MetaADEDB
Dehydration ADReCS
Delirium ADReCS
Delusion ADReCS
Dementia ADReCS
Dental Caries ADReCS
Depersonalisation ADReCS
Depressed Level Of Consciousness ADReCS
Depression ADReCS
Depressive Type Psychosis SIDER
Dermatitis ADReCS
Dermatitis Contact ADReCS
Dermatitis Exfoliative ADReCS
Developmental Delay ADReCS
Diabetes Insipidus ADReCS
Diabetes Mellitus ADReCS
Diabetic Ketoacidosis ADReCS
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Disease Progression ADReCS
Disseminated Intravascular Coagulation ADReCS
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drug Eruption ADReCS
Drug Interaction SIDER
Drug Level Increased ADReCS
Dry Mouth ADReCS
Dysarthria ADReCS
Dysgeusia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyspepsia ADReCS
Dysphagia ADReCS
Dysplasia ADReCS
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Dystonia ADReCS
Dysuria ADReCS
Ear Pain ADReCS
Ecchymosis ADReCS
Eczema ADReCS
Effusion ADReCS
Embolism ADReCS
Embolism Pulmonary MetaADEDB
Embolus SIDER
Emphysema MetaADEDB
Encephalopathy ADReCS
Endocrine Disorder SIDER
Endophthalmitis ADReCS
Enlargement Abdomen SIDER
Enterocolitis ADReCS
Eosinophilic Pneumonia ADReCS
Epilepsy Absence MetaADEDB
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Eruption SIDER
Erythema ADReCS
Erythema Multiforme ADReCS
Euphoric Mood ADReCS
Excessive Sleepiness MetaADEDB
Exomphalos ADReCS
Extrapyramidal Disorder ADReCS
Extrasystoles ADReCS
Extremity Contracture MetaADEDB
Eye Disorder SIDER
Face Oedema ADReCS
Facial Paralysis SIDER
Faecal Incontinence ADReCS
Faecalith ADReCS
Faecaloma ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Flat Affect ADReCS
Flatulence ADReCS
Fluid Retention ADReCS
Flushing ADReCS
Food Allergy MetaADEDB
Fungal Skin Infection ADReCS
Furuncle ADReCS
Furunculosis SIDER
Gait Disturbance ADReCS
Gambling MetaADEDB
Gamma-Glutamyltransferase Increased ADReCS
Gastric Cancer ADReCS
Gastric Disorder ADReCS
Gastritis ADReCS
Gastroduodenal Ulcer MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Dysplasia ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gastrointestinal Ulcer ADReCS
Generalised Oedema ADReCS
Gingival Bleeding ADReCS
Glaucoma ADReCS
Globulinuria MetaADEDB
Glossitis ADReCS
Gout ADReCS
Granuloma ADReCS
Granuloma Skin ADReCS
Haematemesis ADReCS
Haematoma ADReCS
Haematuria ADReCS
Haemoglobin ADReCS
Haemoptysis ADReCS
Haemorrhage ADReCS
Hallucination ADReCS
Headache ADReCS
Hemiplegia ADReCS
Henoch-Schonlein Purpura MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis B ADReCS
Hepatitis Cholestatic ADReCS
Hepatitis Fulminant ADReCS
Hepatobiliary Disease SIDER
Hepatocellular Injury ADReCS
Hereditary Disorder SIDER
Hernia ADReCS
Herpes Nos SIDER
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hiccups ADReCS
Hormone Level Abnormal SIDER
Hostility ADReCS
Hyperacusis ADReCS
Hyperalimentation MetaADEDB
Hyperamylasaemia SIDER
Hypercalcaemia ADReCS
Hypercholesterolaemia ADReCS
Hyperhidrosis ADReCS
Hyperkinesis MetaADEDB
Hyperlipidaemia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertonia ADReCS
Hyperventilation ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Oral ADReCS
Hypoalbuminaemia MetaADEDB
Hypochromic Anaemia ADReCS
Hypokalaemia ADReCS
Hypokinesia ADReCS
Hyponatraemia ADReCS
Hypotension ADReCS
Hypothermia ADReCS
Hypotonia ADReCS
Hypoventilation ADReCS
Hypoxia ADReCS
Ild MetaADEDB
Ileus ADReCS
Ill-Defined Disorder ADReCS
Immune System Disorder SIDER
Immunoglobulins Increased ADReCS
Impotence ADReCS
Incontinence ADReCS
Increased Appetite ADReCS
Increased Upper Airway Secretion MetaADEDB
Infarction ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Inflammation ADReCS
Influenza ADReCS
Influenza Like Illness ADReCS
Injection Site Reaction ADReCS
Injection Site Streaking MetaADEDB
Insomnia ADReCS
Intentional Injury ADReCS
Interstitial Lung Disease ADReCS
Intestinal Functional Disorder ADReCS
Intestinal Obstruction ADReCS
Intestinal Resection MetaADEDB
Intracranial Pressure Increased ADReCS
Iron Deficiency ADReCS
Iron Deficiency Anaemia ADReCS
Ischaemia ADReCS
Ischemia MetaADEDB
Jaundice ADReCS
Ketoacidosis ADReCS
Lactic Acidosis ADReCS
Lactic Dehydrogenase Activity Increased SIDER
Large Intestine Perforation MetaADEDB
Laryngitis ADReCS
Leg Cramps ADReCS
Leiomyoma ADReCS
Lethargy ADReCS
Leukocytosis ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Libido Increased ADReCS
Life Support MetaADEDB
Liver Function Test Abnormal ADReCS
Liver Injury ADReCS
Lobar Pneumonia ADReCS
Loss Of Consciousness ADReCS
Lung Disorder ADReCS
Lung Fibrosis MetaADEDB
Lung Infection MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm ADReCS
Lung Neoplasm Malignant ADReCS
Lymphadenopathy ADReCS
Lymphocyte Stimulation Test Positive MetaADEDB
Lymphoma ADReCS
Lymphopenia ADReCS
Major Depression ADReCS
Malaise ADReCS
Mania ADReCS
Manic Psychosis SIDER
Mediastinal Disorder SIDER
Medical Device Complication MetaADEDB
Melaena ADReCS
Meningioma MetaADEDB
Menopausal Disorder MetaADEDB
Mental Disability ADReCS
Mental Disorder SIDER
Mesenteric Artery Embolism ADReCS
Mesenteric Occlusion ADReCS
Methaemoglobinaemia ADReCS
Metrorrhagia ADReCS
Micturition Urgency ADReCS
Migraine ADReCS
Mood Swings ADReCS
Motor Neurone Disease MetaADEDB
Mouth Ulceration ADReCS
Movement Disorders MetaADEDB
Multiple Fractures MetaADEDB
Muscle Atrophy ADReCS
Muscle Relaxant Therapy ADReCS
Muscle Rigidity ADReCS
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness MetaADEDB
Myalgia ADReCS
Myasthenia SIDER
Myasthenia Gravis ADReCS
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Myoclonus ADReCS
Nasal Congestion ADReCS
Nasopharyngitis MetaADEDB
Nausea ADReCS
Necrosis ADReCS
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Neovascularization Pathologic MetaADEDB
Nephritis ADReCS
Nephrolithiasis ADReCS
Nerve Degeneration MetaADEDB
Nerve Root Lesion ADReCS
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neuralgia ADReCS
Neuritis ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
No Therapeutic Response MetaADEDB
Nocturia ADReCS
Nodule ADReCS
Normochromic Normocytic Anaemia ADReCS
Normocytic Anemia SIDER
Nuclear Magnetic Resonance Imaging Brain Abnormal MetaADEDB
Obstruction ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Disorder ADReCS
Oesophageal Stenosis ADReCS
Oesophagitis ADReCS
Opportunistic Infection MetaADEDB
Oral Candidiasis ADReCS
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Osteomyelitis MetaADEDB
Osteonecrosis ADReCS
Osteoporosis ADReCS
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Palpitations ADReCS
Pancreatitis ADReCS
Pancreatitis Acute ADReCS
Pancytopenia ADReCS
Panophthalmitis ADReCS
Paraesthesia ADReCS
Paraesthesia Oral ADReCS
Paralysis ADReCS
Paraneoplastic Syndrome MetaADEDB
Paranoia ADReCS
Paranoid Reaction SIDER
Parathyroid Disorder ADReCS
Pco2 Decreased MetaADEDB
Pemphigoid ADReCS
Pericarditis ADReCS
Peripheral Embolism ADReCS
Peripheral Neuritis ADReCS
Peripheral Vascular Disorder ADReCS
Peritonitis ADReCS
Personality Disorder ADReCS
Petechiae ADReCS
Phlebitis ADReCS
Phobia ADReCS
Phosphatase Alkaline Increased SIDER
Photophobia ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Platelet Count Decreased ADReCS
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pneumonia ADReCS
Pneumonia Respiratory Syncytial Viral MetaADEDB
Pneumothorax ADReCS
Po2 Decreased MetaADEDB
Pollakiuria ADReCS
Polyp ADReCS
Postmenopausal Haemorrhage ADReCS
Potassium Low SIDER
Priapism ADReCS
Proctalgia ADReCS
Proctitis ADReCS
Prostate Cancer ADReCS
Prostate Cancer Metastatic MetaADEDB
Prostate Carcinoma SIDER
Prostatic Disorder ADReCS
Prothrombin Time Shortened ADReCS
Pruritus ADReCS
Pseudomembranous Colitis ADReCS
Pseudomembranous Enterocolitis SIDER
Psoriasis ADReCS
Psychiatric Symptom ADReCS
Psychotic Disorder ADReCS
Pulmonary Arrest MetaADEDB
Pulmonary Artery Thrombosis MetaADEDB
Pulmonary Embolism ADReCS
Pulmonary Function Test Decreased ADReCS
Pulmonary Oedema ADReCS
Pulmonary Toxicity ADReCS
Purpura ADReCS
Pyelonephritis ADReCS
Radial Nerve Palsy ADReCS
Radiculopathy ADReCS
Rash ADReCS
Rash Generalised MetaADEDB
Reaction Aggravation SIDER
Rectal Tenesmus ADReCS
Red Blood Cell Count Decreased ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment ADReCS
Renal Insufficiency MetaADEDB
Renal Pain ADReCS
Respiratory Acidosis ADReCS
Respiratory Depression ADReCS
Respiratory Disorder ADReCS
Respiratory Distress ADReCS
Respiratory Failure ADReCS
Respiratory Moniliasis ADReCS
Respiratory Rate Increased MetaADEDB
Respiratory Tract Congestion MetaADEDB
Restrictive Pulmonary Disease MetaADEDB
Retinal Diseases MetaADEDB
Retinopathy Of Prematurity MetaADEDB
Rhabdomyolysis ADReCS
Rheumatoid Arthritis ADReCS
Rhinitis ADReCS
Rhinorrhea MetaADEDB
Saliva Altered MetaADEDB
Salivary Gland Enlargement ADReCS
Schizophrenic Reaction SIDER
Schizophreniform Disorder ADReCS
Seborrhoea ADReCS
Seborrhoeic Dermatitis ADReCS
Sedation ADReCS
Seizures MetaADEDB
Sensory Disturbance ADReCS
Sepsis ADReCS
Shock ADReCS
Shoulder Pain ADReCS
Sickness SIDER
Sinusitis ADReCS
Skin Candida ADReCS
Skin Discolouration ADReCS
Skin Disorder ADReCS
Skin Exfoliation ADReCS
Skin Mass ADReCS
Skin Nodule ADReCS
Skin Ulcer ADReCS
Somnolence ADReCS
Sputum Increased ADReCS
Stomatitis ADReCS
Stress MetaADEDB
Stridor ADReCS
Stupor ADReCS
Subarachnoid Haemorrhage ADReCS
Subdural Haematoma ADReCS
Sudden Cardiac Death MetaADEDB
Sudden Death ADReCS
Suicide SIDER
Suicide Attempt ADReCS
Supraventricular Tachycardia ADReCS
Syncope ADReCS
Tachycardia ADReCS
Talipes ADReCS
Tetany ADReCS
Therapy Non-Responder MetaADEDB
Thinking Abnormal ADReCS
Thirst ADReCS
Thrombocytopenia ADReCS
Thrombocytopenic Purpura ADReCS
Thrombosis ADReCS
Thyroid Neoplasm ADReCS
Tongue Discolouration ADReCS
Tooth Disorder ADReCS
Tooth Impacted ADReCS
Tracheostomy MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Trismus ADReCS
Ulcer ADReCS
Unevaluable Event MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upset Stomach SIDER
Urethral Disorder SIDER
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urine Abnormality ADReCS
Urine Analysis Abnormal ADReCS
Urticaria ADReCS
Uterine Haemorrhage ADReCS
Uterine Leiomyoma ADReCS
Vaginal Moniliasis SIDER
Vascular Purpura ADReCS
Vena Cava Thrombosis MetaADEDB
Ventricular Extrasystoles ADReCS
Ventricular Fibrillation ADReCS
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Vestibular Disorder ADReCS
Viith Nerve Paralysis ADReCS
Volvulus MetaADEDB
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Mycotic Infection ADReCS
Weight Decreased ADReCS
Weight Increased ADReCS
White Blood Cell Count Decreased SIDER
White Blood Cell Count Increased ADReCS
Wrist Drop SIDER
Yawning ADReCS

InAADR: Drug-Protein-ADRs database