InAADR

Drug Information

Drug Name: Aliskiren (173334-57-1)
PubChem ID: 5493444
SMILES: CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N
InchiKey: UXOWGYHJODZGMF-QORCZRPOSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 551.769
LogP: 3.2935
Ring Count: 1
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 146.13

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Pain ADReCS
Abnormal Behaviour MetaADEDB
Abortion Induced MetaADEDB
Accelerated Hypertension MetaADEDB
Aching Muscles MetaADEDB
Acquired Diaphragmatic Eventration MetaADEDB
Acute Hepatic Failure PROTECT
Albumin Urine Present MetaADEDB
Allergic Alveolitis MetaADEDB
Allergic Respiratory Symptom ADReCS
Allergic Vasculitis MetaADEDB
Allergies MetaADEDB
Alopecia MetaADEDB
Anaemia ADReCS
Anal Sphincter Atony MetaADEDB
Anaphylactic Reaction PROTECT
Angina MetaADEDB
Angioedema ADReCS
Animal Bite MetaADEDB
Anticonvulsant Drug Level Decreased MetaADEDB
Aortic Disorder MetaADEDB
Aortic Dissection MetaADEDB
Aortic Stenosis MetaADEDB
Apathy MetaADEDB
Apnea MetaADEDB
Appendectomy MetaADEDB
Appendicitis MetaADEDB
Arthralgia ADReCS
Arthritis Reactive MetaADEDB
Asthenia ADReCS
Ataxia Telangiectasia SIDER
Atrioventricular Extrasystoles MetaADEDB
Atrophy Of Skin MetaADEDB
Autoimmune Thyroiditis MetaADEDB
Back Pain ADReCS
Bence Jones Protein Urine MetaADEDB
Benign Gastric Neoplasm MetaADEDB
Benign Oesophageal Neoplasm MetaADEDB
Benign Small Intestinal Neoplasm MetaADEDB
Benign Tumour Excision MetaADEDB
Biopsy Bone Marrow Abnormal MetaADEDB
Biopsy Kidney MetaADEDB
Bladder Dilatation MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Albumin Increased MetaADEDB
Blood Aldosterone Increased MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Gases Abnormal MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased ADReCS
Blood Pressure Abnormal MetaADEDB
Blood Pressure Diastolic MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid Increased ADReCS
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Brain Stem Ischaemia MetaADEDB
Bronchial Neoplasm MetaADEDB
Bronchitis ADReCS
Bronchoalveolar Lavage Abnormal MetaADEDB
Burning Sensation MetaADEDB
Calculus Of Kidney SIDER
Cardiac Asthma MetaADEDB
Cardiac Output Increased MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardioversion MetaADEDB
Cartilage Development Disorder MetaADEDB
Catheter Placement MetaADEDB
Catheter Removal MetaADEDB
Choking Sensation MetaADEDB
Chronic Hepatic Failure MetaADEDB
Chronic Lymphocytic Leukaemia Recurrent MetaADEDB
Chronic Respiratory Failure MetaADEDB
Circumoral Oedema MetaADEDB
Clonic Convulsion ADReCS
Colon Cancer ADReCS
Computerised Tomogram MetaADEDB
Concomitant Disease Aggravated MetaADEDB
Concomitant Disease Progression MetaADEDB
Congenital Anomaly ADReCS
Congenital Cystic Kidney Disease MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coronary Artery Bypass MetaADEDB
Cortical Laminar Necrosis MetaADEDB
Cough ADReCS
Creatinine Increased SIDER
Creatinine Renal Clearance Decreased MetaADEDB
Creatinine Renal Clearance Increased MetaADEDB
Creatinine Urine Decreased MetaADEDB
Death MetaADEDB
Death Of Relative MetaADEDB
Deglutition Disorder MetaADEDB
Delusional Perception MetaADEDB
Dermatitis ADReCS
Developmental Delay ADReCS
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Disease Progression MetaADEDB
Disorder Renal MetaADEDB
Diverticulosis MetaADEDB
Dizziness ADReCS
Drug Administered At Inappropriate Site MetaADEDB
Drug Ineffective MetaADEDB
Drug Interaction SIDER
Drug Physiologic Incompatibility MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Cough ADReCS
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dyspnoea At Rest MetaADEDB
Dyssomnia MetaADEDB
Echocardiogram MetaADEDB
Echocardiogram Abnormal MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Electroencephalogram Abnormal ADReCS
Endocarditis MetaADEDB
Endotracheal Intubation MetaADEDB
Enterocolitis Infectious MetaADEDB
Epistaxis ADReCS
Eruption MetaADEDB
Erythema PROTECT
Erythema Of Eyelid MetaADEDB
Esophageal Cancer MetaADEDB
Esophageal Ulcer MetaADEDB
Extrasystoles MetaADEDB
Eye Infection MetaADEDB
Eye Oedema MetaADEDB
Eye Swelling MetaADEDB
Eyelid Retraction MetaADEDB
Eyelids Pruritus MetaADEDB
Facial Flushing MetaADEDB
Fasting ADReCS
Fatigue ADReCS
Feeling Abnormal MetaADEDB
Food Allergy MetaADEDB
Forced Expiratory Volume Decreased MetaADEDB
Gallbladder Enlargement MetaADEDB
Gallbladder Operation MetaADEDB
Gastric Adenoma MetaADEDB
Gastric Infection MetaADEDB
Gastric Mucosal Lesion MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Gastrostomy Tube Insertion MetaADEDB
Globulinuria MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Glomerular Vascular Disorder MetaADEDB
Glomerulonephritis Rapidly Progressive MetaADEDB
Glucose Tolerance Test Abnormal MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Gout ADReCS
Grand Mal Convulsion ADReCS
Haematocrit Decreased ADReCS
Haematological Malignancy MetaADEDB
Haemoglobin Decreased PROTECT
Haemorrhagic Infarction MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Hepatic Enzyme Increased PROTECT
Hepatic Failure PROTECT
Hepatic Trauma MetaADEDB
Hepatitis PROTECT
Hepatitis A MetaADEDB
High Blood Pressure MetaADEDB
Hip Swelling MetaADEDB
Humerus Fracture MetaADEDB
Hyperkalaemia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertensive SIDER
Hyperventilation MetaADEDB
Hypotension ADReCS
Hypotonia MetaADEDB
Implantable Defibrillator Insertion MetaADEDB
Infection ADReCS
Influenza ADReCS
Insomnia ADReCS
Intestinal Mass MetaADEDB
Intestinal Resection MetaADEDB
Intubation MetaADEDB
Itch MetaADEDB
Jaundice PROTECT
Kidney Pain MetaADEDB
Kidney Small MetaADEDB
Labile Blood Pressure MetaADEDB
Laryngeal Disorder MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Life Support MetaADEDB
Light Sensitivity MetaADEDB
Lip Discolouration MetaADEDB
Lip Dry MetaADEDB
Lip Swelling PROTECT
Lipids Abnormal MetaADEDB
Liver Disorder PROTECT
Loss Of Consciousness ADReCS
Low Cardiac Output Syndrome MetaADEDB
Lymphedema MetaADEDB
Macroglossia MetaADEDB
Macula Lutea Degeneration MetaADEDB
Mean Cell Haemoglobin Decreased MetaADEDB
Mean Cell Volume Decreased MetaADEDB
Mean Platelet Volume Decreased MetaADEDB
Medical Device Removal MetaADEDB
Medication Residue MetaADEDB
Mesenteric Artery Embolism MetaADEDB
Metamyelocyte Count Increased MetaADEDB
Microalbuminuria MetaADEDB
Micturition Frequency Decreased MetaADEDB
Monocyte Percentage Increased MetaADEDB
Mouth Bleeding MetaADEDB
Mucosal Dryness MetaADEDB
Mucosal Haemorrhage MetaADEDB
Mucous Stools MetaADEDB
Muscle Spasms ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Mutism MetaADEDB
Myositis ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Pain ADReCS
Negative Thoughts MetaADEDB
Neoplasm Malignant ADReCS
Nephrolithiasis ADReCS
Norepinephrine Increased MetaADEDB
Normal Newborn MetaADEDB
Ocular Icterus MetaADEDB
Odynophagia MetaADEDB
Oedema ADReCS
Oedema Mucosal MetaADEDB
Oedema Peripheral ADReCS
Oesophageal Dysplasia MetaADEDB
Oesophageal Mucosal Hyperplasia MetaADEDB
Oligohydramnios ADReCS
Oliguria ADReCS
Oral Disorder PROTECT
Organic Erectile Dysfunction MetaADEDB
Oropharyngeal Pain ADReCS
Orthopnea MetaADEDB
Osteitis Deformans MetaADEDB
Oxygen Saturation Abnormal MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Pain In Throat MetaADEDB
Palpitation MetaADEDB
Palpitations PROTECT
Pancreatic Calcification MetaADEDB
Pancreatic Enzymes Increased MetaADEDB
Peptic Ulcer Perforation MetaADEDB
Periorbital Oedema ADReCS
Petechia MetaADEDB
Phaeochromocytoma MetaADEDB
Pharyngeal Oedema PROTECT
Pharyngolaryngeal Pain SIDER
Photosensitive Rash MetaADEDB
Platelet Aggregation MetaADEDB
Pneumonia Klebsiella MetaADEDB
Pollakiuria MetaADEDB
Poor Peripheral Circulation MetaADEDB
Porokeratosis MetaADEDB
Productive Cough MetaADEDB
Protein Total Increased MetaADEDB
Pruritus PROTECT
Pruritus Generalised MetaADEDB
Pseudomonal Sepsis MetaADEDB
Psychosomatic Disease MetaADEDB
Pulmonary Artery Dilatation MetaADEDB
Pulmonary Hypertension MetaADEDB
Rash ADReCS
Renal Artery Stenosis MetaADEDB
Renal Artery Stent Placement MetaADEDB
Renal Cyst MetaADEDB
Renal Failure Acute PROTECT
Renal Function Test Abnormal MetaADEDB
Renal Impairment PROTECT
Renal Ischaemia MetaADEDB
Renin Decreased MetaADEDB
Renin Increased MetaADEDB
Respiratory Tract Infection ADReCS
Resuscitation MetaADEDB
Retrograde Amnesia MetaADEDB
Rhabdomyolysis ADReCS
Rhinitis ADReCS
Rhinovirus Infection MetaADEDB
Rhonchi MetaADEDB
Seizures SIDER
Sensation Of Heaviness MetaADEDB
Shoulder Pain ADReCS
Skin Plaque MetaADEDB
Skin Reaction PROTECT
Skin Swelling MetaADEDB
Sleep Disorder MetaADEDB
Social Phobia MetaADEDB
Staphylococcal Skin Infection MetaADEDB
Stevens-Johnson Syndrome PROTECT
Surgery MetaADEDB
Swelling ADReCS
Swelling Face ADReCS
Swollen Tongue PROTECT
Therapy Responder MetaADEDB
Throat Cancer MetaADEDB
Throat Tightness MetaADEDB
Thyroid Cancer MetaADEDB
Thyroid Haemorrhage MetaADEDB
Thyroidectomy MetaADEDB
Tonic-Clonic Seizures SIDER
Toxic Epidermal Necrolysis PROTECT
Tracheal Disorder MetaADEDB
Tracheobronchitis MetaADEDB
Transferrin Saturation Decreased MetaADEDB
Transferrin Saturation Increased MetaADEDB
Transfusion MetaADEDB
Ultrasound Chest MetaADEDB
Ultrasound Kidney MetaADEDB
Ultrasound Scan Abnormal MetaADEDB
Upper Respiratory Tract Infection ADReCS
Uric Acid Level Increased SIDER
Urinary Tract Infection ADReCS
Urine Albumin/Creatinine Ratio MetaADEDB
Urine Odour Abnormal MetaADEDB
Urine Output Increased MetaADEDB
Urticaria PROTECT
Uterine Pain MetaADEDB
Venous Insufficiency MetaADEDB
Vertigo ADReCS
Weight Abnormal MetaADEDB
Weight Gain MetaADEDB

InAADR: Drug-Protein-ADRs database