InAADR

Drug Information

Drug Name: Bendamustine (16506-27-7)
PubChem ID: 65628
SMILES: CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O
InchiKey: YTKUWDBFDASYHO-UHFFFAOYSA-N
Therapeutic Category: Alkylating Agents, Antineoplastic Agents, Noxae

Computed Drug Properties

Molecular Weight (dalton): 358.269
LogP: 3.2646
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 58.36

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Accelerated Hypertension MetaADEDB
Acute Hepatic Failure MetaADEDB
Adenopathy MetaADEDB
Allergic Pharyngitis MetaADEDB
Allergic Vasculitis MetaADEDB
Allergies MetaADEDB
Alveolitis MetaADEDB
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anemia Aplastic MetaADEDB
Angiopathy ADReCS
Anorexia ADReCS
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aphagia MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arthralgia ADReCS
Aseptic Necrosis Bone MetaADEDB
Asthenia ADReCS
Atelectasis MetaADEDB
Atypical Pneumonia SIDER
Back Ache MetaADEDB
Back Pain ADReCS
Biopsy Bone Abnormal MetaADEDB
Blood Bilirubin Increased ADReCS
Blood Creatinine Increased ADReCS
Blood In Urine MetaADEDB
Blood Uric Acid Increased ADReCS
Body Temperature Increased ADReCS
Bone Fracture Spontaneous MetaADEDB
Bone Marrow Disorder MetaADEDB
Bone Marrow Failure ADReCS
Bone Pain ADReCS
Bronchoalveolar Lavage MetaADEDB
Bronchoscopy MetaADEDB
Candidiasis ADReCS
Capillary Leak Syndrome MetaADEDB
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiomyopathy MetaADEDB
Catheter Site Pain ADReCS
Cell Death ADReCS
Cerebral Aspergillosis MetaADEDB
Chest Pain ADReCS
Chill MetaADEDB
Chills ADReCS
Connective Tissue Disorder SIDER
Constipated MetaADEDB
Constipation ADReCS
Coordination Abnormal MetaADEDB
Cough ADReCS
Creatinine Increased SIDER
Crohn Disease MetaADEDB
Cryoglobulinaemia MetaADEDB
Cyanosis MetaADEDB
Cytolysis ADReCS
Decreased Appetite ADReCS
Dehydration ADReCS
Dental Care MetaADEDB
Dental Operation MetaADEDB
Depression ADReCS
Dermal Cyst MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Dizziness ADReCS
Dry Mouth ADReCS
Dry Skin ADReCS
Duodenal Ulcer MetaADEDB
Duodenitis MetaADEDB
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Electrocardiogram Qt Prolonged MetaADEDB
Embolism Pulmonary MetaADEDB
Erosive Gastritis MetaADEDB
Erythema ADReCS
Escherichia Urinary Tract Infection MetaADEDB
Excess Potassium MetaADEDB
Exophthalmos MetaADEDB
Failure To Thrive MetaADEDB
Fatigue ADReCS
Febrile Neutropenia ADReCS
Feeling Abnormal ADReCS
Fibrosis ADReCS
Fluid Intake Reduced MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Glaucoma MetaADEDB
Haemoglobin Decreased ADReCS
Haemolysis ADReCS
Haemolytic Anaemia MetaADEDB
Haemorrhagic Transformation Stroke MetaADEDB
Haemorrhagic Tumour Necrosis MetaADEDB
Headache ADReCS
Hepatitis Acute MetaADEDB
Herpes Nos SIDER
Herpes Simplex ADReCS
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertensive SIDER
Hypertensive Crisis ADReCS
Hyperuricaemia ADReCS
Hypocalcaemia ADReCS
Hypokalaemia ADReCS
Hyponatraemia ADReCS
Hypophagia MetaADEDB
Hypotension ADReCS
Idiopathic Thrombocytopenic Purpura MetaADEDB
Ild MetaADEDB
Ill-Defined Disorder ADReCS
Immune System Disorder SIDER
Infection ADReCS
Infection Viral MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Inflammation ADReCS
Infusion Related Reaction ADReCS
Infusion Site Pain ADReCS
Insomnia ADReCS
Jugular Vein Thrombosis MetaADEDB
Leucopenia MetaADEDB
Leukopenia ADReCS
Leukostasis MetaADEDB
Lung Edema MetaADEDB
Lung Lobectomy MetaADEDB
Lymphocyte Count Decreased ADReCS
Lymphocytes Decreased MetaADEDB
Lymphoma MetaADEDB
Lymphopenia ADReCS
Malaise ADReCS
Mediastinal Disorder SIDER
Meningitides MetaADEDB
Mental Disorder SIDER
Mesenteric Vein Thrombosis MetaADEDB
Mucosal Inflammation ADReCS
Multifocal Leukoencephalopathy MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Mycosis Fungoides MetaADEDB
Myelodysplastic Syndrome ADReCS
Myelosuppression SIDER
Myopathy Toxic MetaADEDB
Nasal Congestion ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Necrosis ADReCS
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neutropenia ADReCS
Neutrophil Count Decreased ADReCS
Night Sweats ADReCS
Nocardiosis MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Optic Neuropathy MetaADEDB
Oral Candidiasis ADReCS
Oral Herpes MetaADEDB
Oral Surgery MetaADEDB
Oropharyngeal Pain ADReCS
Osteoarthritis MetaADEDB
Overdose MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Palsies MetaADEDB
Pancytopenia ADReCS
Paraproteinaemia MetaADEDB
Parophthalmia MetaADEDB
Periorbital Oedema ADReCS
Pertussis MetaADEDB
Pharyngolaryngeal Pain SIDER
Phlebitis ADReCS
Platelet Count MetaADEDB
Platelet Count Decreased ADReCS
Pneumocystis Jiroveci Infection MetaADEDB
Pneumonia ADReCS
Pneumonia Mycoplasmal ADReCS
Pneumonia Primary Atypical ADReCS
Pneumothorax MetaADEDB
Pruritus ADReCS
Pulmonary Fibrosis ADReCS
Pulmonary Sepsis MetaADEDB
Pyrexia ADReCS
Radiotherapy MetaADEDB
Rash ADReCS
Reactive Perforating Collagenosis MetaADEDB
Renal Failure ADReCS
Renal Failure Acute ADReCS
Respiratory Tract Infection ADReCS
Reversible Airways Obstruction MetaADEDB
Rhonchi MetaADEDB
Sepsis ADReCS
Serum Ferritin Increased MetaADEDB
Sinusitis ADReCS
Skin Exfoliation ADReCS
Skin Irritation ADReCS
Skin Necrosis ADReCS
Skin Reaction ADReCS
Somnolence ADReCS
Spinal X-Ray MetaADEDB
Splint Application MetaADEDB
Sputum Discoloured MetaADEDB
Stomatitis ADReCS
Subclavian Vein Thrombosis MetaADEDB
Supraventricular Tachycardia MetaADEDB
Sweating SIDER
Swelling ADReCS
Systemic Mycosis MetaADEDB
Tachycardia ADReCS
Therapeutic Response Decreased MetaADEDB
Thrombocytopenia ADReCS
Toxic Epidermal Necrolysis ADReCS
Transaminases Increased MetaADEDB
Tumour Lysis Syndrome ADReCS
Ulcer Haemorrhage MetaADEDB
Upper Gastrointestinal Bleeding MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Venous Thrombosis Limb MetaADEDB
Vomiting ADReCS
Weakness SIDER
Weight Decreased ADReCS
Wheezing ADReCS
White Blood Cell Count Decreased ADReCS

InAADR: Drug-Protein-ADRs database