| Drug Name: | sabcomeline (159912-53-5) |
|---|---|
| PubChem ID: | 9577995 |
| SMILES: | CO/N=C(C#N)/[C@H]1CN2CCC1CC2 |
| InchiKey: | IQWCBYSUUOFOMF-QTLFRQQHSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 193.25 |
| LogP | : | 0.85418 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 48.62 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Bradycardia | Muscarinic acetylcholine receptor M2 (P08172) | Sabcomeline produced bradycardia through the low-affinity state of the M(2) receptor. [ ADR Type 1 ] | Low-affinity M(2) receptor binding state mediates mouse atrial bradycardia: comparative effects of carbamylcholine and the M(1) receptor aGOnists sabcomeline and xanomeline |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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