InAADR: Drug-Protein-ADRs database

Drug Name:	Clemastine (15686-51-8)
PubChem ID:	26987
SMILES:	CC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCCC3CCCN3C
InchiKey:	YNNUSGIPVFPVBX-NHCUHLMSSA-N
Therapeutic Category:

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug	Toxicity	Interaction Type	Mechanism	Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity	Interacting Protein	Mechanism	Reference
Constipation	Histamine H1 receptor (P35367)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Constipation	Kappa-Type opioid receptor (P41145)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Dry Mouth	Histamine H1 receptor (P35367)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Dry Mouth	Kappa-Type opioid receptor (P41145)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Insomnia	Histamine H1 receptor (P35367)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Nervousness	Neuropeptide S receptor (Q6W5P4)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Palpitations	Neuropeptide S receptor (Q6W5P4)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Sleep Disorder	Prostaglandin G/H synthase 1 precursor (P23219)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Tachycardia	Kappa-Type opioid receptor (P41145)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets
Tremor	Androgen receptor (P10275)	Not Available	Large-scale prediction and testing of drug activity on side-effect targets

This panel provides drug-food interactions and their ADRs along with references

Food	Toxicity	Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite	Toxicity	Place of Metabolism	Mechanism	Reference

This panel provides information on drug category

Toxicity	Source
Agitation	ADReCS
Agranulocytosis	ADReCS
Anaemia	ADReCS
Anaphylactic Shock	ADReCS
Anorexia	ADReCS
Asthenia	ADReCS
Chest Discomfort	ADReCS
Chest Pain	ADReCS
Chest Tightness	ADReCS
Chills	ADReCS
Confusional State	ADReCS
Constipation	ADReCS
Conversion Disorder	ADReCS
Convulsion	ADReCS
Coordination Abnormal	ADReCS
Decreased Appetite	ADReCS
Dermatitis	ADReCS
Diarrhoea	ADReCS
Diplopia	ADReCS
Dizziness	ADReCS
Drowsiness	SIDER
Drug Eruption	ADReCS
Dry Mouth	ADReCS
Dry Throat	ADReCS
Dyspepsia	ADReCS
Epigastric Distress	SIDER
Euphoric Mood	ADReCS
Extrasystoles	ADReCS
Fatigue	ADReCS
Feeling Abnormal	ADReCS
Haemolytic Anaemia	ADReCS
Headache	ADReCS
Hyperhidrosis	ADReCS
Hypotension	ADReCS
Hysteria	ADReCS
Increased Bronchial Secretion	ADReCS
Insomnia	ADReCS
Irritability	ADReCS
Labyrinthitis	ADReCS
Micturition Disorder	ADReCS
Nasal Congestion	ADReCS
Nausea	ADReCS
Nervousness	ADReCS
Neuritis	ADReCS
Neuropathy Peripheral	ADReCS
Palpitations	ADReCS
Paraesthesia	ADReCS
Photosensitivity	SIDER
Photosensitivity Reaction	ADReCS
Pollakiuria	ADReCS
Rash	ADReCS
Restlessness	ADReCS
Sedation	ADReCS
Shock	ADReCS
Somnolence	ADReCS
Sweating	SIDER
Sweating Increased	SIDER
Tachycardia	ADReCS
Tension	ADReCS
Thrombocytopenia	ADReCS
Tinnitus	ADReCS
Tremor	ADReCS
Urinary Retention	ADReCS
Urticaria	ADReCS
Vertigo	ADReCS
Vision Blurred	ADReCS
Vomiting	ADReCS
Wheezing	ADReCS

Molecular Weight (dalton)	:	343.898
LogP	:	5.1044
Ring Count	:	2
Hydrogen Bond Acceptor Count	:	2
Hydrogen Bond Donor Count	:	0
Total Polar Surface Area	:	12.47