Drug Name: | Capecitabine (154361-50-9) |
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PubChem ID: | 60953 |
SMILES: | CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@H]2[C@@H]([C@@H]([C@H](O2)C)O)O |
InchiKey: | GAGWJHPBXLXJQN-UORFTKCHSA-N |
Therapeutic Category: | Antimetabolites, Antineoplastic Agents, Noxae |
Molecular Weight (dalton) | : | 359.354 |
LogP | : | 0.7602 |
Ring Count | : | 1 |
Hydrogen Bond Acceptor Count | : | 8 |
Hydrogen Bond Donor Count | : | 3 |
Total Polar Surface Area | : | 122.91 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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Folic Acid (59-30-3) | Diarrhoea | Synergistic | concurrent use of folic acid enhanced capecitabine toxicity | Lethal toxicity of capecitabine due to abusive folic acid prescription? |
Folic Acid (59-30-3) | Hand-And-Foot Syndrome | Synergistic | concurrent use of folic acid enhanced capecitabine toxicity | Lethal toxicity of capecitabine due to abusive folic acid prescription? |
Folic Acid (59-30-3) | Vomiting | Synergistic | concurrent use of folic acid enhanced capecitabine toxicity | Lethal toxicity of capecitabine due to abusive folic acid prescription? |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category