| Drug Name: | Carmustine (154-93-8) |
|---|---|
| PubChem ID: | 2578 |
| SMILES: | C(CCl)NC(=O)N(CCCl)N=O |
| InchiKey: | DLGOEMSEDOSKAD-UHFFFAOYSA-N |
| Therapeutic Category: | Alkylating Agents, Antineoplastic Agents, Noxae |
| Molecular Weight (dalton) | : | 214.052 |
| LogP | : | 1.157 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 61.77 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Cimetidine (51481-61-9) | Bone Marrow Depression | Synergistic | Studies in animals suggest that cimetidine impairs the clearance of carmustine | H2-antagonists and carmustine |
| Cimetidine (51481-61-9) | Leucopenia | Synergistic | Studies in animals suggest that cimetidine impairs the clearance of carmustine | H2-antagonists and carmustine |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Response Of Glioma | Methylated-DNA--protein-cysteine methyltransferase (P16455) | Response of glioma to carmustine. [ ADR Type 2 ] | The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category