| Drug Name: | Thioguanine (154-42-7) |
|---|---|
| PubChem ID: | 2723601 |
| SMILES: | C1=NC2=C(N1)C(=S)N=C(N2)N |
| InchiKey: | WYWHKKSPHMUBEB-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 167.197 |
| LogP | : | 0.59769 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 3 |
| Total Polar Surface Area | : | 83.38 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Busulfan (55-98-1) | Hepatic Nodular Hyperplasia | Synergistic | Not known | Oesophageal varices associated with busulphan-thioguanine combination therapy for chronic myeloid leukaemia |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Myelotoxicity | Thiopurine S-methyltransferase (P51580) | Myelotoxicity [ ADR Type 2 ] | Pharmacogenetics in cancer chemotherapy: balancing toxicity and response |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category