InAADR

Drug Information

Drug Name: Nitrazepam (146-22-5)
PubChem ID: 4506
SMILES: C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3
InchiKey: KJONHKAYOJNZEC-UHFFFAOYSA-N
Therapeutic Category: Anti-Anxiety Agents, Anticonvulsants, Central Nervous System Agents, Central Nervous System Depressants, GABA Agents, GABA Modulators, Hypnotics and Sedatives, Neurotransmitter Agents, Psychotropic Drugs, Tranquilizing Agents

Computed Drug Properties

Molecular Weight (dalton): 281.271
LogP: 2.3843
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 84.6

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abnormal Behaviour MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Movements MetaADEDB
Abulia MetaADEDB
Abuse MetaADEDB
Accidental Drug Intake By Child MetaADEDB
Acetonaemia MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Activation Syndrome MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Abdomen MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Failure MetaADEDB
Acute Stress Disorder MetaADEDB
Adams-Stokes Syndrome MetaADEDB
Adenoidal Disorder MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Affective Disorder MetaADEDB
Afib MetaADEDB
Aggression ADReCS
Agitated MetaADEDB
Agitation ADReCS
Agoraphobia MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Allergic Granulomatous Angiitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Anal Haemorrhage MetaADEDB
Anger ADReCS
Angle Closure Glaucoma MetaADEDB
Anorexia MetaADEDB
Anterograde Amnesia MetaADEDB
Anti-Insulin Antibody MetaADEDB
Anti-Insulin Antibody Decreased MetaADEDB
Antibody Test Abnormal MetaADEDB
Anticholinergic Syndrome MetaADEDB
Antidepressant Drug Level Increased MetaADEDB
Anuria MetaADEDB
Anxiety ADReCS
Aortic Dissection MetaADEDB
Apallic Syndrome MetaADEDB
Apathy MetaADEDB
Apgar Score Low MetaADEDB
Apnea MetaADEDB
Apprehension SIDER
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arthritis Rheumatoid MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Ataxia ADReCS
Atonic Seizures MetaADEDB
Atrioventricular Block MetaADEDB
Atrioventricular Block Complete MetaADEDB
Attempted Suicide MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Autoimmune Thyroiditis MetaADEDB
Autonomic Failure Syndrome MetaADEDB
Back Ache MetaADEDB
Bacterial Infection MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Bed Rest MetaADEDB
Bedridden MetaADEDB
Biopsy Heart MetaADEDB
Biopsy Skin MetaADEDB
Bipolar I Disorder MetaADEDB
Birth Trauma MetaADEDB
Black Stools MetaADEDB
Bladder Retention MetaADEDB
Bleb MetaADEDB
Blepharal Pigmentation MetaADEDB
Blood Alkaline Phosphatase Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Cholinesterase Decreased MetaADEDB
Blood Cortisol Increased MetaADEDB
Blood Creatine Phosphokinase Abnormal MetaADEDB
Blood Creatine Phosphokinase Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Immunoglobulin A Decreased MetaADEDB
Blood Immunoglobulin G Decreased MetaADEDB
Blood Immunoglobulin M Decreased MetaADEDB
Blood Lactate Dehydrogenase Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Ph Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Decreased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blunted Affect MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Fracture MetaADEDB
Bone Marrow Failure MetaADEDB
Bradypnoea MetaADEDB
Brain Oedema MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Caesarean Section MetaADEDB
Calcium Metabolism Disorder MetaADEDB
Calculus Urinary MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Aneurysm MetaADEDB
Cardiac Death MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Hypertrophy MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardioversion MetaADEDB
Cartilage Development Disorder MetaADEDB
Catalepsy MetaADEDB
Cataplexy MetaADEDB
Catheter Related Infection MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebral Circulatory Failure MetaADEDB
Chest Infection MetaADEDB
Chicken Pox MetaADEDB
Choking MetaADEDB
Chromaturia MetaADEDB
Chylothorax MetaADEDB
Cirrhosis MetaADEDB
Clavicle Fracture MetaADEDB
Clubbing MetaADEDB
Cognition Disorders MetaADEDB
Cognitive Disorder MetaADEDB
Cold Sweat MetaADEDB
Colitis Collagenous MetaADEDB
Colostomy MetaADEDB
Coma MetaADEDB
Communication Disorder MetaADEDB
Completed Suicide MetaADEDB
Compulsions MetaADEDB
Condition Aggravated MetaADEDB
Confusion MetaADEDB
Confusional State ADReCS
Congenital Nystagmus MetaADEDB
Congenital Tricuspid Valve Atresia MetaADEDB
Congenital Tricuspid Valve Stenosis MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Conversion Disorder MetaADEDB
Coordination Abnormal MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cyanosis MetaADEDB
Cyanosis Neonatal MetaADEDB
Cytomegalovirus Antibody Positive MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Decreased Activity MetaADEDB
Decubitus Ulcer MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Delirium ADReCS
Delirium Tremens ADReCS
Delusion MetaADEDB
Delusion Of Grandeur MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressed Mood MetaADEDB
Depression Suicidal MetaADEDB
Depressive Disorder MetaADEDB
Dermabrasion MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Developmental Delay MetaADEDB
Diaphragmalgia MetaADEDB
Diarrhoea ADReCS
Diet Refusal MetaADEDB
Differential White Blood Cell Count Abnormal MetaADEDB
Dilatation Ventricular MetaADEDB
Disease Of Liver MetaADEDB
Disorientation ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dissociative Disorder MetaADEDB
Diverticulum Intestinal Haemorrhagic MetaADEDB
Dizziness ADReCS
Drowsiness SIDER
Drug Exposure During Pregnancy MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal MetaADEDB
Drug Withdrawal Syndrome Neonatal MetaADEDB
Dry Skin MetaADEDB
Duodenal Perforation MetaADEDB
Dysarthria MetaADEDB
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Early Morning Awakening MetaADEDB
Educational Problem MetaADEDB
Ejaculation Disorder MetaADEDB
Electric Shock MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrolyte Disorder MetaADEDB
Embolism Pulmonary MetaADEDB
Emotional Distress ADReCS
Emphysema MetaADEDB
Encephalitis Allergic MetaADEDB
Energy Increased MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epidermolysis MetaADEDB
Epilepsy MetaADEDB
Erosive Gastritis MetaADEDB
Erythema Infectiosum MetaADEDB
Erythropenia MetaADEDB
Euphoric Mood MetaADEDB
Excess Potassium MetaADEDB
Excessive Salivation MetaADEDB
Excessive Thirst MetaADEDB
Excitement SIDER
Eyelash Thickening MetaADEDB
Face Injury MetaADEDB
Faecal Incontinence MetaADEDB
Fatigue ADReCS
Fear Of Death MetaADEDB
Fear Of Eating MetaADEDB
Fecal Incontinence MetaADEDB
Feeding Disorder Neonatal MetaADEDB
Feeding Problem In Newborn MetaADEDB
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Feeling Guilty MetaADEDB
Fibrin D Dimer MetaADEDB
Fibrin Degradation Products Increased MetaADEDB
Finger Hypoplasia MetaADEDB
Flight Of Ideas MetaADEDB
Fluid Intake Reduced MetaADEDB
Foetal Alcohol Syndrome MetaADEDB
Fractured Pelvis Nos MetaADEDB
Gait Disturbance ADReCS
Galactorrhea MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrectomy MetaADEDB
Gastric Disorder ADReCS
Gastric Lavage MetaADEDB
Gastric Ulcer Perforated MetaADEDB
Gastric Varices MetaADEDB
Gastric Volvulus MetaADEDB
Gastrointestinal Perforation MetaADEDB
Gastrointestinal Stoma Complication MetaADEDB
Gaze Palsy MetaADEDB
Gingival Hypertrophy MetaADEDB
Glossitis MetaADEDB
Granulocyte Count Decreased MetaADEDB
Haematemesis MetaADEDB
Haemodialysis MetaADEDB
Haemoglobin Abnormal MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhoids MetaADEDB
Haemostasis MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Hangover ADReCS
Headache ADReCS
Heartburn ADReCS
Hemiplegia MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis Alcoholic MetaADEDB
Hepatitis Fulminant MetaADEDB
Hiccough MetaADEDB
High Blood Pressure MetaADEDB
Hostility MetaADEDB
Human Herpes Virus 6 Serology Positive MetaADEDB
Human Herpesvirus 6 Infection MetaADEDB
Hyperalimentation MetaADEDB
Hyperhidrosis MetaADEDB
Hyperkinesia ADReCS
Hyperkinesis MetaADEDB
Hyperprolactinaemia MetaADEDB
Hypertonia Neonatal MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Unconsciousness MetaADEDB
Hypokinesia Neonatal MetaADEDB
Hypophagia MetaADEDB
Hypoplastic Right Heart Syndrome MetaADEDB
Hypotension ADReCS
Hypothermia Neonatal MetaADEDB
Hypotonia Neonatal MetaADEDB
Hypoventilation Neonatal MetaADEDB
Hypoxia MetaADEDB
Hypoxic Encephalopathy MetaADEDB
Ild MetaADEDB
Ill-Defined Disorder MetaADEDB
Impulsive Behaviour MetaADEDB
Inappropriate Schedule Of Drug Administration MetaADEDB
Incoherent MetaADEDB
Incontinence MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infusion Site Extravasation MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Injection Site Ulcer MetaADEDB
Injury Asphyxiation MetaADEDB
Intention Tremor MetaADEDB
Intubation MetaADEDB
Iris Hyperpigmentation MetaADEDB
Irritability ADReCS
Jaw Fracture MetaADEDB
Jugular Vein Distension MetaADEDB
Kidney Failure MetaADEDB
Kidney Pain MetaADEDB
Lacrimal Disorder MetaADEDB
Lethargy ADReCS
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Lichenoid Keratosis MetaADEDB
Lightheadedness SIDER
Lipogranuloma MetaADEDB
Local Swelling MetaADEDB
Logorrhoea MetaADEDB
Long Qt Syndrome MetaADEDB
Lordosis MetaADEDB
Loss Of Consciousness ADReCS
Lung Consolidation MetaADEDB
Lung Fibrosis MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lymphatic Duct Rupture MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Morphology Abnormal MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Lymphocytic Infiltration MetaADEDB
Macrocytosis MetaADEDB
Malnourished MetaADEDB
Mania MetaADEDB
Masked Facies MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mean Cell Haemoglobin Decreased MetaADEDB
Mean Cell Volume Decreased MetaADEDB
Melaena Neonatal MetaADEDB
Menstrual Disorder MetaADEDB
Metamyelocyte Count Increased MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastatic Pain MetaADEDB
Microcephaly MetaADEDB
Miosis MetaADEDB
Mouth Ulcer MetaADEDB
Movement Disorders MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Murder MetaADEDB
Muscle Hypotonia MetaADEDB
Muscle Spasticity ADReCS
Mutism MetaADEDB
Myelocyte Count Increased MetaADEDB
Myocardial Fibrosis MetaADEDB
Myoglobin Blood Increased MetaADEDB
Myoglobin Urine Present MetaADEDB
Nail Disorder MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Negativism MetaADEDB
Neonatal Asphyxia MetaADEDB
Neonatal Respiratory Acidosis MetaADEDB
Nephrogenic Diabetes Insipidus MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nightmare ADReCS
Normal Newborn MetaADEDB
Nystagmus MetaADEDB
Nystagmus Pathologic MetaADEDB
Obsessive Thoughts MetaADEDB
Oculogyration MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Oedema Mucosal MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oliguria MetaADEDB
Optic Nerve Hypoplasia MetaADEDB
Oral Intake Reduced MetaADEDB
Oral Mucosal Petechiae MetaADEDB
Overdose MetaADEDB
Pallor MetaADEDB
Palpitations ADReCS
Pancreatic Cancer MetaADEDB
Panic Disorder MetaADEDB
Panniculitis MetaADEDB
Paresthesia MetaADEDB
Parkinson MetaADEDB
Pco2 Increased MetaADEDB
Pedal Pulse Absent MetaADEDB
Pericarditis MetaADEDB
Peritonitis MetaADEDB
Peritonsillar Abscess MetaADEDB
Persecutory Delusion MetaADEDB
Personality Change MetaADEDB
Petechia MetaADEDB
Platelet Aggregation MetaADEDB
Platelet Count MetaADEDB
Platelet Transfusion MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumonia Herpes Viral MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumothorax MetaADEDB
Po2 MetaADEDB
Po2 Decreased MetaADEDB
Poor Sucking Reflex MetaADEDB
Poriomania MetaADEDB
Portal Hypertension MetaADEDB
Postrenal Failure MetaADEDB
Potentiating Drug Interaction MetaADEDB
Pressure Of Speech MetaADEDB
Protein Total Decreased MetaADEDB
Psoriasis MetaADEDB
Psychiatric Symptom MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorder ADReCS
Psychotic Disorders MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Infarction MetaADEDB
Pulse Pressure Decreased MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Pyelonephritis Acute MetaADEDB
Pyloric Stenosis MetaADEDB
Quadriplegia MetaADEDB
Rage SIDER
Rebound Effect MetaADEDB
Renal Impairment MetaADEDB
Respiratory Failure MetaADEDB
Reticulocyte Count Increased MetaADEDB
Retinal Vascular Disorder MetaADEDB
Rhabdomyolysis MetaADEDB
Right Heart Failure MetaADEDB
Scab MetaADEDB
Schizophrenia MetaADEDB
Screaming MetaADEDB
Sedation ADReCS
Seizures MetaADEDB
Seizures Febrile MetaADEDB
Self Injurious Behaviour MetaADEDB
Self Mutilation MetaADEDB
Sexual Abuse MetaADEDB
Shock ADReCS
Shoplifting MetaADEDB
Shunt Malfunction MetaADEDB
Shunt Occlusion MetaADEDB
Sigmoidoscopy Abnormal MetaADEDB
Skin Laceration MetaADEDB
Skin Oedema MetaADEDB
Sleep Disorder MetaADEDB
Sleep Disorders MetaADEDB
Sleep Phase Rhythm Disturbance MetaADEDB
Sleep Walking MetaADEDB
Small For Dates Baby MetaADEDB
Soliloquy MetaADEDB
Somnolence ADReCS
Spasmodic Dysphonia MetaADEDB
Specific Gravity Urine Increased MetaADEDB
Speech Disorder MetaADEDB
Speech Disorders MetaADEDB
Spleen Congestion MetaADEDB
Sputum Culture Positive MetaADEDB
Staggering SIDER
Stress Symptoms MetaADEDB
Stridor MetaADEDB
Subcutaneous Abscess MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sudden Death MetaADEDB
Suicidal Behaviour MetaADEDB
Syncope ADReCS
Syphilis MetaADEDB
Systemic Mycosis MetaADEDB
Tachycardia Ventricular MetaADEDB
Tension ADReCS
Thought Insertion MetaADEDB
Thrombophlebitis MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Transurethral Prostatectomy MetaADEDB
Treatment Noncompliance MetaADEDB
Tumour Compression MetaADEDB
Twin Pregnancy MetaADEDB
Upset Stomach SIDER
Urinary Incontinence MetaADEDB
Urine Sodium MetaADEDB
Venous Pressure Jugular Increased MetaADEDB
Ventricular Fibrillation MetaADEDB
Victim Of Homicide MetaADEDB
Viith Nerve Paralysis MetaADEDB
Violent SIDER
Violent Behavior SIDER
Vision Blurred ADReCS
Vomiting ADReCS
Water Intoxication MetaADEDB
Weakness SIDER
Weight Gain MetaADEDB
Yawning MetaADEDB

InAADR: Drug-Protein-ADRs database