InAADR

Drug Information

Drug Name: Nefopam (13669-70-0)
PubChem ID: 4450
SMILES: CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3
InchiKey: RGPDEAGGEXEMMM-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 253.345
LogP: 3.238
Ring Count: 2
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 12.47

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abnormal Eeg MetaADEDB
Abuse MetaADEDB
Acute Abdomen MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenopathy MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Anaphylactic Reaction MetaADEDB
Angle Closure Glaucoma MetaADEDB
Anoxic Encephalopathy MetaADEDB
Anuria MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arthritis Rheumatoid MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asthmatic Crisis MetaADEDB
Aura MetaADEDB
Av Dissociation MetaADEDB
Bacteria Stool Identified MetaADEDB
Bacterial Test Positive MetaADEDB
Bacterial Toxaemia MetaADEDB
Bacteroides Infection MetaADEDB
Balance Disorder MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Adenoma MetaADEDB
Biliary Fibrosis MetaADEDB
Bladder Inflammation MetaADEDB
Blindness Transient MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Osmolarity Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Uric Acid Decreased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Abscess MetaADEDB
Bone Marrow Failure MetaADEDB
Bradycardia MetaADEDB
Brain Death MetaADEDB
Calcinosis MetaADEDB
Calciphylaxis MetaADEDB
Candida Infection MetaADEDB
Candida Sepsis MetaADEDB
Capnocytophagia Infection MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Ischemia MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiopulmonary Failure MetaADEDB
Cerebral Toxoplasmosis MetaADEDB
Cerebral Venous Thrombosis MetaADEDB
Cholangiolitis MetaADEDB
Cholinergic Syndrome MetaADEDB
Chronic Respiratory Failure MetaADEDB
Cmv Infection MetaADEDB
Coma MetaADEDB
Complex Partial Seizures MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Congenital Pyelocaliectasis MetaADEDB
Contracture MetaADEDB
Conversion Disorder MetaADEDB
Convulsions Grand Mal MetaADEDB
Creatinine Renal Clearance Decreased MetaADEDB
Csf White Blood Cell Count Positive MetaADEDB
Culture Positive MetaADEDB
Culture Stool Negative MetaADEDB
Cytolytic Hepatitis MetaADEDB
Denervation Atrophy MetaADEDB
Dental Caries MetaADEDB
Dental Necrosis MetaADEDB
Dental Prosthesis Placement MetaADEDB
Depressive Symptom MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disease Recurrence MetaADEDB
Disorder Lung MetaADEDB
Dizziness MetaADEDB
Drug Interaction MetaADEDB
Duodenal Ulcer Perforation MetaADEDB
Embolism MetaADEDB
Encephalopathy MetaADEDB
Endodontic Procedure MetaADEDB
Enlarged Liver MetaADEDB
Enterobacter Infection MetaADEDB
Enterococcal Sepsis MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Eruption MetaADEDB
Escherichia Infection MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Extrapyramidal Disorder MetaADEDB
Facial Bones Fracture MetaADEDB
Faecal Vomiting MetaADEDB
Foetal Arrhythmia MetaADEDB
Foetal Growth Retardation MetaADEDB
Foetal Heart Rate MetaADEDB
Food Intolerance MetaADEDB
Foreign Body Aspiration MetaADEDB
Fungal Sepsis MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Ischaemia MetaADEDB
Gastrointestinal Tract Mucosal Discolouration MetaADEDB
General Physical Condition MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Genital Ulceration MetaADEDB
Gingival Disorder MetaADEDB
Globulinuria MetaADEDB
Granulocytes Maturation Arrest MetaADEDB
Granulocytosis MetaADEDB
Haematemesis MetaADEDB
Haematoma MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhagic Anaemia MetaADEDB
Hallucinations MetaADEDB
Hepatic Artery Thrombosis MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Haematoma MetaADEDB
Hepatitis MetaADEDB
Hepatitis Acute MetaADEDB
Hepatitis C MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatocellular Injury MetaADEDB
Herpes Virus Infection MetaADEDB
High Blood Pressure MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Human Herpesvirus 8 Infection MetaADEDB
Hyperalgesia MetaADEDB
Hyperchloraemia MetaADEDB
Hypokalaemia MetaADEDB
Hypophosphataemia MetaADEDB
Hypothermia MetaADEDB
Hypovolaemic Shock MetaADEDB
Hypoxia MetaADEDB
Iatrogenic Injury MetaADEDB
Ild MetaADEDB
Ileitis MetaADEDB
Incision Site Haematoma MetaADEDB
Increased Platelet Count MetaADEDB
Injection Site Thrombosis MetaADEDB
Joint Ankylosis MetaADEDB
Kaposi Sarcoma MetaADEDB
Kidney Failure MetaADEDB
Leucopenia MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia Neonatal MetaADEDB
Lipase MetaADEDB
Listeriosis MetaADEDB
Liver Abscess MetaADEDB
Loose Tooth MetaADEDB
Lung Neoplasm MetaADEDB
Lyell MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphocytosis MetaADEDB
Malignant Melanoma MetaADEDB
Mania MetaADEDB
Meningeal Disorder MetaADEDB
Meningitides MetaADEDB
Meningorrhagia MetaADEDB
Mixed Hepatocellular-Cholestatic Injury MetaADEDB
Monocytosis MetaADEDB
Mononucleosis Syndrome MetaADEDB
Monoplegia MetaADEDB
Muscle Inflammation MetaADEDB
Nausea MetaADEDB
Necrotising Fasciitis MetaADEDB
Nephrotic Syndrome MetaADEDB
Oliguria MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain Postoperative MetaADEDB
Palatal Oedema MetaADEDB
Pallor MetaADEDB
Pedal Pulse Absent MetaADEDB
Pericardial Effusion MetaADEDB
Peripheral Ischaemia MetaADEDB
Peripheral Nerve Lesion MetaADEDB
Peritoneal Effusion MetaADEDB
Periventricular Leukomalacia MetaADEDB
Persecutory Delusion MetaADEDB
Phlebitis MetaADEDB
Platelet Count MetaADEDB
Pleural Disorder MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumothorax MetaADEDB
Poor Personal Hygiene MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Procedural Haematoma MetaADEDB
Premature Baby MetaADEDB
Product Quality Issue MetaADEDB
Prothrombin Level Decreased MetaADEDB
Pruritus Generalised MetaADEDB
Pulmonary Arterial Hypertension MetaADEDB
Rales MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Disorder MetaADEDB
Resuscitation MetaADEDB
Reversible Posterior Leukoencephalopathy Syndrome MetaADEDB
Saliva Altered MetaADEDB
Seizures MetaADEDB
Septic Shock MetaADEDB
Serratia Infection MetaADEDB
Shock Haemorrhagic MetaADEDB
Sinus Bradycardia MetaADEDB
Skin Plaque MetaADEDB
Small Intestinal Stenosis MetaADEDB
Staphylococcal Abscess MetaADEDB
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Stem Cell Transplant MetaADEDB
Stenotrophomonas Infection MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subileus MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Tachycardia MetaADEDB
Thrombophlebitis MetaADEDB
Tooth Loss MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Tryptase Increased MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vertigo MetaADEDB
Vitamin A Deficiency MetaADEDB
Walking Disability MetaADEDB
Withdrawal Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database