InAADR

Drug Information

Drug Name: Palonosetron (135729-61-2)
PubChem ID: 6337614
SMILES: C1C[C@@H]2CN(C(=O)C3=C2C(=CC=C3)C1)[C@@H]4CN5CCC4CC5
InchiKey: CPZBLNMUGSZIPR-NVXWUHKLSA-N
Therapeutic Category: Neurotransmitter Agents, Serotonin Agents, Serotonin Antagonists

Computed Drug Properties

Molecular Weight (dalton): 296.414
LogP: 2.6565
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 23.55

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Acidosis ADReCS
Alanine Aminotransferase Increased ADReCS
Alopecia ADReCS
Amblyopia ADReCS
Anaemia ADReCS
Anaphylactic Reaction PROTECT
Anaphylactic Shock PROTECT
Anaphylactoid Reaction PROTECT
Anaphylactoid Shock PROTECT
Anorexia ADReCS
Anxiety ADReCS
Arrhythmia ADReCS
Arthralgia ADReCS
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Atrioventricular Block SIDER
Atrioventricular Block First Degree SIDER
Atrioventricular Block Second Degree SIDER
Blood Bilirubin Increased ADReCS
Blood Pressure Decreased ADReCS
Body Temperature Increased ADReCS
Bradycardia ADReCS
Chills ADReCS
Constipation ADReCS
Convulsion ADReCS
Cyanosis ADReCS
Decreased Appetite ADReCS
Dermatitis ADReCS
Dermatitis Allergic ADReCS
Dermatitis Atopic ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Distention SIDER
Dizziness ADReCS
Dizziness Postural ADReCS
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Electrocardiogram Qt Prolonged ADReCS
Electrocardiogram Qtc Interval Prolonged ADReCS
Electrocardiogram T Wave Amplitude Decreased ADReCS
Electrolyte Imbalance ADReCS
Epistaxis ADReCS
Erythema ADReCS
Euphoric Mood ADReCS
Extrasystoles ADReCS
Eye Irritation ADReCS
Eye Swelling ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Hot PROTECT
Flatulence ADReCS
Fluid Retention ADReCS
Gasping SIDER
Gastritis ADReCS
Gastrointestinal Hypomotility ADReCS
Gastrointestinal Pain ADReCS
Generalised Oedema ADReCS
Glycosuria ADReCS
Headache ADReCS
Hepatic Enzyme Increased ADReCS
Hiccups ADReCS
Hot Flush ADReCS
Hyperbilirubinaemia PROTECT
Hyperglycaemia ADReCS
Hyperkalaemia ADReCS
Hypersensitivity ADReCS
Hypersomnia ADReCS
Hypertension ADReCS
Hypocalcaemia PROTECT
Hypokalaemia ADReCS
Hypotension ADReCS
Hypoventilation ADReCS
Hypoxia ADReCS
Ill-Defined Disorder ADReCS
Induration ADReCS
Infection ADReCS
Influenza ADReCS
Influenza Like Illness ADReCS
Injection Site Discomfort PROTECT
Injection Site Induration PROTECT
Injection Site Pain PROTECT
Injection Site Reaction ADReCS
Insomnia ADReCS
Ischaemia ADReCS
Joint Stiffness ADReCS
Laryngospasm ADReCS
Malaise ADReCS
Menopausal Symptoms ADReCS
Metabolic Acidosis ADReCS
Metabolic Disorder PROTECT
Motion Sickness ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Myocardial Ischaemia ADReCS
Oedema ADReCS
Pain ADReCS
Pain In Extremity ADReCS
Pallor ADReCS
Paraesthesia ADReCS
Peripheral Sensory Neuropathy PROTECT
Platelet Count Decreased ADReCS
Pruritus ADReCS
Pruritus Generalised ADReCS
Pyrexia ADReCS
Rash ADReCS
Rash Pruritic PROTECT
Respiratory Failure ADReCS
Salivary Hypersecretion ADReCS
Sickness SIDER
Sinus Arrhythmia ADReCS
Sinus Bradycardia ADReCS
Sinus Tachycardia ADReCS
Sinusitis ADReCS
Somnolence ADReCS
Stiffness SIDER
Supraventricular Extrasystoles ADReCS
Swelling ADReCS
Tachycardia ADReCS
Tinnitus ADReCS
Transaminases Increased ADReCS
Urinary Retention ADReCS
Vasodilatation ADReCS
Vein Discolouration ADReCS
Ventricular Extrasystoles ADReCS
Weakness SIDER

InAADR: Drug-Protein-ADRs database