Drug Name: | Kaolin (1332-58-7) |
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PubChem ID: | 56841936 |
SMILES: | O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O |
InchiKey: | NLYAJNPCOHFWQQ-UHFFFAOYSA-N |
Therapeutic Category: |
Molecular Weight (dalton) | : | 258.159 |
LogP | : | -3.853 |
Ring Count | : | 0 |
Hydrogen Bond Acceptor Count | : | 7 |
Hydrogen Bond Donor Count | : | 0 |
Total Polar Surface Area | : | 158.97 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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Lincomycin (154-21-2) | Diarrhoea | Antagonistic | It seems probable that the lincomycin becomes adsorbed onto the kaolin, thereby reducing its bioavailability. The kaolin also coats the lining of the gut and acts as a physical barrier to absorption | Pharmacokinetic evaluation of a drug interaction between kaolin--pectin and clindamycin |
Clindamycin (18323-44-9) | Diarrhoea | Antagonistic | It seems probable that the lincomycin becomes adsorbed onto the kaolin, thereby reducing its bioavailability. The kaolin also coats the lining of the gut and acts as a physical barrier to absorption | Pharmacokinetic evaluation of a drug interaction between kaolin--pectin and clindamycin |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
Toxicity | Source |
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Arthritis Experimental | MetaADEDB |
Hydrocephalus | MetaADEDB |
Hyperalgesia | MetaADEDB |
Pain | MetaADEDB |