InAADR

Drug Information

Drug Name: Chlorphenamine (132-22-9)
PubChem ID: 2725
SMILES: CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
InchiKey: SOYKEARSMXGVTM-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 274.795
LogP: 3.8186
Ring Count: 2
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 16.13

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Phenytoin (57-41-0) Involuntary Jaw Movements Synergistic The reason for these reactions is not clear but it has been suggested that chlorphenamine may have inhibited the metabolism of phenytoin by the liver. Involuntary movements caused by phenytoin intoxication in epileptic patients

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal tenderness MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Sinusitis MetaADEDB
Adenopathy MetaADEDB
Adhesion MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Agranulocytosis ADReCS
Alanine Aminotransferase Increased MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Granulomatous Angiitis MetaADEDB
Amnesia MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anaphylaxis MetaADEDB
Anemia Aplastic MetaADEDB
Anorexia ADReCS
Aphthous Stomatitis MetaADEDB
Aptyalism MetaADEDB
Arthritis Rheumatoid MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Asthmatic Crisis MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Atrophy Of Skin MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Basedow Disease MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Bleb MetaADEDB
Bleeding Gums MetaADEDB
Blepharospasm MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Sodium MetaADEDB
Blurred Vision MetaADEDB
Body Temperature Increased MetaADEDB
Brain Contusion MetaADEDB
Brain Herniation MetaADEDB
Brain Oedema MetaADEDB
Bronchial Spasm MetaADEDB
Bronchiectasis MetaADEDB
Bunion MetaADEDB
Burning Sensation Mucosal MetaADEDB
Campylobacter Gastroenteritis MetaADEDB
Candida Pneumonia MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cartilage Development Disorder MetaADEDB
Caustic Injury MetaADEDB
Cerebellar Infarction MetaADEDB
Cerebral Haemorrhage MetaADEDB
Chest Discomfort ADReCS
Chest Pain ADReCS
Chest Tightness ADReCS
Chill MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Chronic Kidney Disease MetaADEDB
Cold Sweat MetaADEDB
Compression Fracture MetaADEDB
Concomitant Disease Aggravated MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Congenital Heart Disease MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Constipation ADReCS
Contracture MetaADEDB
Contrast Media Allergy MetaADEDB
Conversion Disorder ADReCS
Convulsion ADReCS
Cytogenetic Abnormality MetaADEDB
Cytomegalovirus Enterocolitis MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Delayed Effects Of Radiation MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Dermographism MetaADEDB
Diarrhea Infectious MetaADEDB
Diarrhoea ADReCS
Difficulty In Walking MetaADEDB
Diplopia ADReCS
Disease Of Liver MetaADEDB
Disorders Of Excessive Somnolence MetaADEDB
Diverticular Perforation MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Administration Error MetaADEDB
Drug Eruption ADReCS
Drug Eruptions MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Hypersensitivity MetaADEDB
Dry Mouth ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyspepsia ADReCS
Dystonia MetaADEDB
Easy Bruisability MetaADEDB
Eating Disorder MetaADEDB
Eczema MetaADEDB
Effusion MetaADEDB
Encephalitis MetaADEDB
Endometrial Hyperplasia MetaADEDB
Endotracheal Intubation MetaADEDB
Enteritis MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Increased MetaADEDB
Epigastric Distress SIDER
Epiglottic Oedema MetaADEDB
Epstein-Barr Virus Associated Lymphoproliferative Disorder MetaADEDB
Eruption MetaADEDB
Erythema MetaADEDB
Erythema Multiforme MetaADEDB
Erythema Nodosum MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Euphoric Mood ADReCS
Extrasystoles Ventricular MetaADEDB
Facial Flushing MetaADEDB
Fatigue ADReCS
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Fluid Imbalance MetaADEDB
Fungal Disease MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Cancer MetaADEDB
Gastroenteritis MetaADEDB
General Physical Health Deterioration MetaADEDB
Haematoma Infection MetaADEDB
Haemodynamic Instability MetaADEDB
Haemolytic Anaemia ADReCS
Headache MetaADEDB
Hematoma Subdural MetaADEDB
Hemiplegia MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Fibrosis MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatitis MetaADEDB
Hepatitis B MetaADEDB
Hepatoblastoma MetaADEDB
Hepatocellular Damage MetaADEDB
High Risk Pregnancy MetaADEDB
Hyperhidrosis ADReCS
Hyperkinesis MetaADEDB
Hypersensitivity MetaADEDB
Hypertension MetaADEDB
Hypertension Pulmonary MetaADEDB
Hyperthyroidism MetaADEDB
Hypomagnesaemia MetaADEDB
Hypophosphataemia MetaADEDB
Hysteria ADReCS
Ild MetaADEDB
Immunosuppressant Drug Level MetaADEDB
Increased Appetite MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Infusion Related Reaction MetaADEDB
Injection Site Erythema MetaADEDB
Insect Bites And Stings MetaADEDB
Insomnia ADReCS
Intentional Drug Misuse MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Irritability ADReCS
Itch MetaADEDB
Jaw Disorder MetaADEDB
Jejunal Ulcer MetaADEDB
Joint Injury MetaADEDB
Labyrinthitis ADReCS
Leukopenia Neonatal MetaADEDB
Light Sensitivity MetaADEDB
Limb Reduction Defect MetaADEDB
Lower Limb Fracture MetaADEDB
Lung Consolidation MetaADEDB
Lung Fibrosis MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lyell MetaADEDB
Lymph Node Calcification MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Lymphangiosis Carcinomatosa MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Macular Oedema MetaADEDB
Malabsorption MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mediastinal Disorder MetaADEDB
Mediastinitis MetaADEDB
Metastases To Abdominal Cavity MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Metastases To Meninges MetaADEDB
Mucosal Inflammation MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Muscular Diseases MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Myelitis MetaADEDB
Nasal Congestion ADReCS
Nausea ADReCS
Necrosis MetaADEDB
Nephrotic Syndrome MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neuritis ADReCS
Neuropathy Peripheral ADReCS
Neutropenic Sepsis MetaADEDB
No Therapeutic Response MetaADEDB
Nystagmus MetaADEDB
Oculogyric Crisis MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Osteitis Deformans MetaADEDB
Ovarian Cancer MetaADEDB
Ovarian Haemorrhage MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain MetaADEDB
Pallor MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Panic Disorder MetaADEDB
Paraesthesia ADReCS
Paroxysmal Nocturnal Haemoglobinuria MetaADEDB
Periarthritis MetaADEDB
Periodontitis MetaADEDB
Peritonitis MetaADEDB
Petechia MetaADEDB
Phlebitis MetaADEDB
Photosensitivity MetaADEDB
Photosensitivity Reaction ADReCS
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pollakiuria ADReCS
Postmenopausal Bleeding MetaADEDB
Premature Labour MetaADEDB
Prostate Cancer Metastatic MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus MetaADEDB
Pruritus Generalised MetaADEDB
Pulmonary Edema MetaADEDB
Pyoderma Gangrenosum MetaADEDB
Rash ADReCS
Rebound Effect MetaADEDB
Red Blood Cell Sedimentation Rate Decreased MetaADEDB
Renal Abscess MetaADEDB
Renal Atrophy MetaADEDB
Renal Impairment MetaADEDB
Respiratory Insufficiency MetaADEDB
Respiratory Tract Infections MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retroperitoneal Haematoma MetaADEDB
Rhinitis Allergic Perennial MetaADEDB
Rhinitis Allergic Seasonal MetaADEDB
Scratch MetaADEDB
Sedation ADReCS
Seizures MetaADEDB
Shock ADReCS
Skull Malformation MetaADEDB
Small Intestinal Obstruction MetaADEDB
Sneezing MetaADEDB
Somnolence ADReCS
Spondylosis MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stomach Ulcer MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subdural Empyema MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sweating MetaADEDB
Sweating Increased MetaADEDB
Tension ADReCS
Terminal State MetaADEDB
Tetany MetaADEDB
Thrombocytopenia ADReCS
Thrombotic Microangiopathy MetaADEDB
Tinea Pedis MetaADEDB
Tinnitus ADReCS
Toxic Skin Eruption MetaADEDB
Tracheobronchitis MetaADEDB
Tremor ADReCS
Trisomy 21 MetaADEDB
Unevaluable Event MetaADEDB
Upper Respiratory Tract Inflammation MetaADEDB
Urinary Retention ADReCS
Urine Abnormality MetaADEDB
Urticaria MetaADEDB
Vacuolar Myopathy MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Wheezing ADReCS

InAADR: Drug-Protein-ADRs database