InAADR

Drug Information

Drug Name: Verteporfin (129497-78-5)
PubChem ID:
SMILES: CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C
InchiKey: YTZALCGQUPRCGW-ZSFNYQMMSA-N
Therapeutic Category: Dermatologic Agents, Photosensitizing Agents, Radiation-Sensitizing Agents

Computed Drug Properties

Molecular Weight (dalton): 718.807
LogP: 6.52696
Ring Count: 4
Hydrogen Bond Acceptor Count: 9
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 173.56

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Pain MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accidental Exposure MetaADEDB
Accommodation Disorder MetaADEDB
Acetonaemia MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acute Leukaemia MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Administration Site Pain MetaADEDB
Adrenal Neoplasm MetaADEDB
Adrenocortical Insufficiency Chronic MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Albuminuria ADReCS
Allergic Dermatitis MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anaphylactic Reaction MetaADEDB
Angina Unstable MetaADEDB
Angiogram Abnormal MetaADEDB
Angiopathy ADReCS
Angle Closure Glaucoma MetaADEDB
Anion Gap Decreased MetaADEDB
Anosmia MetaADEDB
Anoxic Encephalopathy MetaADEDB
Anxiety MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arthralgia ADReCS
Arthropathy ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Asthmatic Crisis MetaADEDB
Atrial Fibrillation ADReCS
Atrioventricular Block MetaADEDB
Atrophy MetaADEDB
Auricular Swelling MetaADEDB
Autoimmune Hepatitis MetaADEDB
Automatism MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bile Duct Obstruction MetaADEDB
Biliary Tract Disorder MetaADEDB
Bladder Cancer MetaADEDB
Bladder Inflammation MetaADEDB
Bleb MetaADEDB
Blepharitis ADReCS
Blepharoptosis MetaADEDB
Blindness ADReCS
Blindness Unilateral MetaADEDB
Blood Creatinine Increased ADReCS
Blood In Urine MetaADEDB
Blood Iron Abnormal MetaADEDB
Blood Pressure Fluctuation ADReCS
Body Odor SIDER
Body Temperature Increased ADReCS
Bone Marrow Failure MetaADEDB
Bone Pain MetaADEDB
Brain Oedema MetaADEDB
Bulging MetaADEDB
Bundle Branch Block Left MetaADEDB
Burns Second Degree MetaADEDB
Burns Third Degree MetaADEDB
C-Reactive Protein Increased MetaADEDB
Caesarean Section MetaADEDB
Capillary Disorder MetaADEDB
Carbohydrate Antigen 15-3 MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Ischemia MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathy MetaADEDB
Cataract ADReCS
Cerebellar Infarction MetaADEDB
Cerebral Hypoperfusion MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Ischaemia MetaADEDB
Change In Blood Pressure SIDER
Chest Pain ADReCS
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Chorioretinal Atrophy MetaADEDB
Chorioretinal Disorder MetaADEDB
Chorioretinal Scar MetaADEDB
Choroidal Dystrophy MetaADEDB
Choroidal Haemorrhage MetaADEDB
Choroidal Infarction MetaADEDB
Choroidal Neovascularisation MetaADEDB
Choroiditis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Coma MetaADEDB
Completed Suicide MetaADEDB
Complex Partial Seizures MetaADEDB
Condition Aggravated MetaADEDB
Conjunctival Disorder MetaADEDB
Conjunctival Hyperaemia ADReCS
Conjunctivitis ADReCS
Connective Tissue Disease MetaADEDB
Constipation ADReCS
Convulsion MetaADEDB
Corneal Scar MetaADEDB
Corneal Staining MetaADEDB
Cough ADReCS
Cramp MetaADEDB
Creatinine Increased SIDER
Csf Protein MetaADEDB
Cyanosis MetaADEDB
Cytolytic Hepatitis MetaADEDB
Deafness ADReCS
Deafness Congenital MetaADEDB
Deafness Unilateral MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Detached Retina MetaADEDB
Detachment Of Retinal Pigment Epithelium MetaADEDB
Detachment Psychological SIDER
Diarrhea MetaADEDB
Diplopia ADReCS
Discomfort ADReCS
Disease Progression MetaADEDB
Disease Recurrence MetaADEDB
Disorder Of Globe MetaADEDB
Disorder Retinal MetaADEDB
Dissociation ADReCS
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye ADReCS
Dry Skin MetaADEDB
Dysgeusia MetaADEDB
Dyspepsia MetaADEDB
Dyspnoea ADReCS
Ear Lobe Infection MetaADEDB
Early Morning Awakening MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Eczema ADReCS
Edema Extremities MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Emesis MetaADEDB
Encephalitis MetaADEDB
Encephalitis Herpes MetaADEDB
Enteritis Infectious MetaADEDB
Eosinophilia ADReCS
Epidural Hematoma MetaADEDB
Epilepsy MetaADEDB
Erythema MetaADEDB
Escherichia Infection MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Extensor Plantar Response MetaADEDB
Extravasation ADReCS
Extremity Pain MetaADEDB
Exudative Retinopathy MetaADEDB
Eye Laser Scar MetaADEDB
Eye Oedema MetaADEDB
Eye Penetration MetaADEDB
Eye Pruritus ADReCS
Faecal Occult Blood Positive MetaADEDB
Fatigue MetaADEDB
Feeling Abnormal ADReCS
Fib MetaADEDB
Flashing Lights MetaADEDB
Flat Anterior Chamber Of Eye MetaADEDB
Flushing ADReCS
Formication MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Cancer Metastatic ADReCS
Gastrointestinal Carcinoma ADReCS
Gastrointestinal Injury MetaADEDB
Gastrointestinal Neoplasm Malignant SIDER
General Physical Condition MetaADEDB
General Symptom SIDER
Glaucoma MetaADEDB
Glycosuria ADReCS
Graft Infection MetaADEDB
Haemoglobin ADReCS
Haemolysis MetaADEDB
Haemorrhage ADReCS
Haemorrhagic Cerebral Infarction MetaADEDB
Haemorrhagic Disorder MetaADEDB
Headache ADReCS
Hearing Impaired ADReCS
Heart Attack MetaADEDB
Heart Rate Abnormal ADReCS
Hepatic Enzyme MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Herpes Virus Infection MetaADEDB
Hot Flash MetaADEDB
Hyperaesthesia PROTECT
Hypercholesterolaemia ADReCS
Hyperhidrosis ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypoacusis ADReCS
Hypoaesthesia ADReCS
Hyporeflexia MetaADEDB
Iatrogenic Injury MetaADEDB
Ill-Defined Disorder ADReCS
Incision Site Haemorrhage MetaADEDB
Incontinence MetaADEDB
Infection Viral MetaADEDB
Inflammation ADReCS
Influenza ADReCS
Influenza Like Illness MetaADEDB
Infusion Related Reaction ADReCS
Infusion Site Burning MetaADEDB
Infusion Site Erythema MetaADEDB
Infusion Site Extravasation MetaADEDB
Infusion Site Necrosis MetaADEDB
Infusion Site Oedema MetaADEDB
Infusion Site Pain MetaADEDB
Infusion Site Rash MetaADEDB
Infusion Site Swelling MetaADEDB
Infusion Site Ulcer MetaADEDB
Injection Site Discolouration PROTECT
Injection Site Erosion MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Extravasation PROTECT
Injection Site Haemorrhage ADReCS
Injection Site Hypersensitivity ADReCS
Injection Site Infection MetaADEDB
Injection Site Inflammation ADReCS
Injection Site Irritation MetaADEDB
Injection Site Oedema PROTECT
Injection Site Pain ADReCS
Injection Site Reaction ADReCS
Injection Site Vesicles PROTECT
Intestinal Obstruction MetaADEDB
Ketosis ADReCS
Kidney Failure MetaADEDB
Lacrimal Disorder ADReCS
Lacrimation SIDER
Lacrimation Increased ADReCS
Lacunar Infarction MetaADEDB
Leg Amputation MetaADEDB
Leucopenia MetaADEDB
Leukocyturia MetaADEDB
Lichen Planus MetaADEDB
Liver Function Test Abnormal ADReCS
Loss Of Consciousness ADReCS
Macula Lutea Degeneration MetaADEDB
Macular Hole MetaADEDB
Macular Oedema PROTECT
Macular Pseudohole MetaADEDB
Macular Scar MetaADEDB
Maculopathy MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Mean Cell Volume Decreased MetaADEDB
Meningitis Herpes MetaADEDB
Metamorphopsia MetaADEDB
Middle Insomnia MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Necrosis MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Myasthenia SIDER
Myasthenia Gravis MetaADEDB
Myasthenic Syndrome MetaADEDB
Myocardial Infarction PROTECT
Nail Discolouration MetaADEDB
Nasal Dryness MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Neoplasm Malignant ADReCS
Nerve Degeneration MetaADEDB
Nervous Tension MetaADEDB
Nightmare MetaADEDB
No Match PROTECT
No Therapeutic Response MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Ocular Vascular Disorder MetaADEDB
Oedema ADReCS
Off Label Use MetaADEDB
Osteoarthritis ADReCS
Pain ADReCS
Palatal Oedema MetaADEDB
Pallor MetaADEDB
Palsies MetaADEDB
Peripheral Embolism MetaADEDB
Peripheral Vascular Disorder ADReCS
Peritonitis MetaADEDB
Pharyngitis ADReCS
Pharyngolaryngeal Pain MetaADEDB
Photopsia ADReCS
Photosensitive Rash MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pigmentation Disorder PROTECT
Platelet Count MetaADEDB
Pneumonia ADReCS
Pneumothorax MetaADEDB
Polycythaemia MetaADEDB
Polypoidal Choroidal Vasculopathy MetaADEDB
Poor Quality Drug Administered MetaADEDB
Post Procedural Complication MetaADEDB
Presyncope ADReCS
Procedural Complication MetaADEDB
Prostatic Disorder ADReCS
Prostatitis MetaADEDB
Pruritus ADReCS
Pulmonary Congestion MetaADEDB
Pupil Fixed MetaADEDB
Purulent Discharge MetaADEDB
Pustular Psoriasis MetaADEDB
Pyrexia ADReCS
Raised Liver Function Tests SIDER
Rash ADReCS
Rash Generalised MetaADEDB
Raynaud Phenomenon MetaADEDB
Reading Disorder MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Renal Impairment MetaADEDB
Reperfusion Injury MetaADEDB
Respiratory Failure MetaADEDB
Retinal Bleeding MetaADEDB
Retinal Cyst MetaADEDB
Retinal Degeneration MetaADEDB
Retinal Depigmentation MetaADEDB
Retinal Detachment ADReCS
Retinal Disorder ADReCS
Retinal Dystrophy MetaADEDB
Retinal Exudates MetaADEDB
Retinal Haemorrhage PROTECT
Retinal Infarction MetaADEDB
Retinal Injury MetaADEDB
Retinal Ischaemia MetaADEDB
Retinal Oedema PROTECT
Retinal Pigment Epithelial Tear PROTECT
Retinal Pigment Epitheliopathy MetaADEDB
Retinal Pigmentation MetaADEDB
Retinal Scar MetaADEDB
Retinal Vascular Disorder MetaADEDB
Retinal Vascular Occlusion MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retinopathy Proliferative MetaADEDB
Ruptured Cerebral Aneurysm MetaADEDB
Salivary Gland Cancer MetaADEDB
Scab MetaADEDB
Scar MetaADEDB
Scotoma ADReCS
Shock ADReCS
Skin Desquamation MetaADEDB
Skin Discolouration MetaADEDB
Skin Disorder ADReCS
Skin Injury MetaADEDB
Skin Lesion MetaADEDB
Skin Necrosis MetaADEDB
Skin Odour Abnormal ADReCS
Sleep Disorder ADReCS
Smooth Muscle Antibody Positive MetaADEDB
Soft Tissue Disorder MetaADEDB
Somatoform Disorder MetaADEDB
Spinal Cord Compression MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Streptococcal Bacteraemia MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subcutaneous Emphysema MetaADEDB
Subretinal Fibrosis MetaADEDB
Sweating SIDER
Syncope ADReCS
Syncope Vasovagal MetaADEDB
Therapy Non-Responder MetaADEDB
Tongue Discolouration ADReCS
Transient Ischaemic Attack MetaADEDB
Type Iv Hypersensitivity Reaction MetaADEDB
Urogenital Disorder ADReCS
Urticaria ADReCS
Varicose Vein ADReCS
Vascular Rupture MetaADEDB
Venous Occlusion MetaADEDB
Vertigo ADReCS
Vertigo Positional MetaADEDB
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Acuity Reduced Transiently MetaADEDB
Visual Disturbance ADReCS
Visual Field Defect ADReCS
Visual Impairment ADReCS
Vitreous Haemorrhage ADReCS
Wheeze MetaADEDB
White Blood Cell Count Decreased ADReCS
White Blood Cell Count Increased ADReCS
Wound MetaADEDB

InAADR: Drug-Protein-ADRs database