Drug Name: | Griseofulvin (126-07-8) |
---|---|
PubChem ID: | 441140 |
SMILES: | C[C@@H]1CC(=O)C=C([C@]12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC |
InchiKey: | DDUHZTYCFQRHIY-RBHXEPJQSA-N |
Therapeutic Category: | Anti-Infective Agents, Antifungal Agents |
Molecular Weight (dalton) | : | 352.77 |
LogP | : | 2.8103 |
Ring Count | : | 1 |
Hydrogen Bond Acceptor Count | : | 6 |
Hydrogen Bond Donor Count | : | 0 |
Total Polar Surface Area | : | 71.06 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
---|---|---|---|---|
Phenobarbital (50-06-6) | Abolished Antifungal Effects Of Griseofulvin | Antagonistic | Not fully understood | AN EFFECT OF PHENOBARBITONE ON BLOOD-LEVELS OF GRISEOFULVIN IN MAN |
Bromocriptine (25614-03-3) | Reduce The Efficacy Of Bromocriptine | Antagonistic | Unknown | Metabolic and clinical studies on patients with acromegaly treated with bromocriptine over 22 months |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
---|
This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
---|
This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
---|
This panel provides information on drug category