| Drug Name: | Dextromethorphan (125-71-3) |
|---|---|
| PubChem ID: | 6916184 |
| SMILES: | CN1CC[C@]23CCCC[C@@H]2[C@H]1CC4=C3C=C(C=C4)OC |
| InchiKey: | MKXZASYAUGDDCJ-KBAYOESNSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 271.404 |
| LogP | : | 3.3834 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 12.47 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Linezolid (165800-03-3) | Serotonin Syndrome | Synergistic | concurrent use of linezolid and dextromethorphan resulted in the serotonin syndrome.2 Linezolid has mild reversible MAOI activity, and the serotonin syndrome has been described when dextromethorphan was taken by patients also taking antidepressant MAOIs | Linezolid: pharmacokinetic and pharmacodynamic evaluation of coadministration with pseudoephedrine HCl, phenylpropanolamine HCl, and dextromethorpan HBr |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| Grapefruit Juice | Hallucinations | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
| Grapefruit Juice | Somnolence | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category