InAADR

Drug Information

Drug Name: Tolterodine (124937-51-5)
PubChem ID: 443879
SMILES: CC1=CC(=C(C=C1)O)[C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2
InchiKey: OOGJQPCLVADCPB-HXUWFJFHSA-N
Therapeutic Category: Cholinergic Agents, Cholinergic Antagonists, Muscarinic Antagonists, Neurotransmitter Agents, Urological Agents

Computed Drug Properties

Molecular Weight (dalton): 325.496
LogP: 5.34142
Ring Count: 2
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 23.47

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Mass MetaADEDB
Abdominal Pain ADReCS
Abnormal Gait MetaADEDB
Abnormal Loss Of Weight MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accommodation Disorder ADReCS
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Acquired Oesophageal Web MetaADEDB
Activated Partial Thromboplastin Time Abnormal MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenopathy MetaADEDB
Adjustment Disorder With Depressed Mood MetaADEDB
Adrenal Neoplasm MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Rhinitis MetaADEDB
Alopecia ADReCS
Anaemia ADReCS
Anaesthesia MetaADEDB
Anal Fissure MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Angioedema ADReCS
Anhedonia MetaADEDB
Ankle Fracture MetaADEDB
Anticonvulsant Drug Level Below Therapeutic MetaADEDB
Anuria MetaADEDB
Anxiety ADReCS
Aortic Atherosclerosis MetaADEDB
Aortic Regurgitation MetaADEDB
Aortic Valve Sclerosis MetaADEDB
Apathy MetaADEDB
Aphonia MetaADEDB
Apoplexy MetaADEDB
Appendicitis MetaADEDB
Application Site Dermatitis MetaADEDB
Apraxia MetaADEDB
Aptyalism MetaADEDB
Arterial Disorder MetaADEDB
Arterial Injury MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stenosis MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Arthritis MetaADEDB
Arthropathy MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspiration Pleural Cavity MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Atelectasis MetaADEDB
Aura MetaADEDB
Autoimmune Hepatitis MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Balance Disorder MetaADEDB
Barrett Oesophagus MetaADEDB
Basal Cell Carcinoma MetaADEDB
Bedridden MetaADEDB
Benign Oesophageal Neoplasm MetaADEDB
Bereavement MetaADEDB
Bile Duct Stent Insertion MetaADEDB
Biliary Dyskinesia MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Biopsy MetaADEDB
Bite MetaADEDB
Bk Virus Infection MetaADEDB
Bladder Cancer Recurrent MetaADEDB
Bladder Disorder MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Bladder Spasm MetaADEDB
Blindness ADReCS
Blood 125-Dihydroxycholecalciferol Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood In Urine MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Orthostatic MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea MetaADEDB
Blood Urine Present MetaADEDB
Blurred Vision MetaADEDB
Body Height Decreased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Disorder MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Toxicity MetaADEDB
Bone Scan Abnormal MetaADEDB
Bradypnoea MetaADEDB
Brain Oedema MetaADEDB
Breast Cancer MetaADEDB
Breast Cancer Metastatic MetaADEDB
Breast Cellulitis MetaADEDB
Breast Cyst MetaADEDB
Breast Microcalcification MetaADEDB
Bronchitis ADReCS
Bruise MetaADEDB
Bruxism MetaADEDB
Bulging MetaADEDB
Capillary Leak Syndrome MetaADEDB
Carcinoid Tumour Of The Appendix MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Aneurysm MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Neoplasm Malignant MetaADEDB
Cardioversion MetaADEDB
Carpal Tunnel MetaADEDB
Catheter Placement MetaADEDB
Catheterisation Cardiac MetaADEDB
Cellulitis MetaADEDB
Central Line Infection MetaADEDB
Cerebellar Infarction MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Ischaemia MetaADEDB
Cerumen Impaction MetaADEDB
Cervical Spinal Stenosis MetaADEDB
Cervix Haemorrhage Uterine MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Choking MetaADEDB
Cholecystitis Chronic MetaADEDB
Chronic Active Hepatitis MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Ulcerative Colitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Claustrophobia MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cognitive Disorder MetaADEDB
Colitis MetaADEDB
Colonoscopy MetaADEDB
Compulsive Shopping MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Constipated MetaADEDB
Constipation ADReCS
Costovertebral Angle Tenderness MetaADEDB
Cramp MetaADEDB
Cranial Nerve Disorder MetaADEDB
Csf Protein MetaADEDB
Cutaneous Mycosis MetaADEDB
Cystitis Interstitial MetaADEDB
Cytomegalovirus Colitis MetaADEDB
Dandruff MetaADEDB
Deafness MetaADEDB
Death ADReCS
Debridement MetaADEDB
Decreased Appetite ADReCS
Deep Vein Thromboses MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Delusion ADReCS
Dementia ADReCS
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dental Pain MetaADEDB
Dependence MetaADEDB
Depressed Mood MetaADEDB
Depressive Symptom MetaADEDB
Dermatitis ADReCS
Dermatitis Allergic ADReCS
Dermatitis Psoriasiform MetaADEDB
Dermatosis MetaADEDB
Device Misuse MetaADEDB
Device Related Infection MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Complication MetaADEDB
Diabetic Neuropathy MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Difficulty In Walking MetaADEDB
Disease Recurrence MetaADEDB
Disorder Lung MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Disorientation ADReCS
Disseminated Cytomegaloviral Infection MetaADEDB
Disturbance In Attention MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Drug Delivery System Malfunction MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Effect Increased MetaADEDB
Drug Ineffective MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Dry Skin ADReCS
Dry Throat MetaADEDB
Dysgeusia MetaADEDB
Dyspepsia ADReCS
Dysuria ADReCS
Ear Infection MetaADEDB
Early Morning Awakening MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Economic Problem MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Electrocardiogram Poor R-Wave Progression MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrolyte Disorder MetaADEDB
Emergency Care MetaADEDB
Emotional Distress MetaADEDB
Encephalopathy MetaADEDB
Enlarged Spleen MetaADEDB
Epicondylitis MetaADEDB
Epistaxis MetaADEDB
Erythema MetaADEDB
Erythromelalgia MetaADEDB
Excessive Sleepiness MetaADEDB
Excoriation MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Infection MetaADEDB
Eye Rolling MetaADEDB
Failure To Thrive MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Febrile Neutropenia ADReCS
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Feeling Guilty MetaADEDB
Fibula Fracture MetaADEDB
Flank Pain MetaADEDB
Flatulence ADReCS
Flushing ADReCS
Foreign Body Aspiration MetaADEDB
Formication MetaADEDB
Fractured Pelvis Nos MetaADEDB
Fungal Disease MetaADEDB
Gambling MetaADEDB
Gangrene MetaADEDB
Gastric Disorder MetaADEDB
Gastric Polyps MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Fungal Infection MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Sounds Abnormal MetaADEDB
Gastrooesophageal Reflux Disease ADReCS
Generalised Anxiety Disorder MetaADEDB
Gout MetaADEDB
Granulocytosis MetaADEDB
Grip Strength MetaADEDB
Haemorrhage ADReCS
Haemorrhagic Hepatic Cyst MetaADEDB
Hallucination ADReCS
Hand Fracture MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Valve Incompetence MetaADEDB
Heart Valve Replacement MetaADEDB
Hemiparesis MetaADEDB
Hepatic Enzyme MetaADEDB
Hernia MetaADEDB
Hernia Hiatal MetaADEDB
Herpes Zoster MetaADEDB
High Blood Pressure MetaADEDB
Hip Arthroplasty MetaADEDB
Hip Fracture MetaADEDB
Hospitalisation MetaADEDB
Humerus Fracture MetaADEDB
Hydronephrosis MetaADEDB
Hyperalimentation MetaADEDB
Hyperbilirubinaemia ADReCS
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypersexuality MetaADEDB
Hypertensive Cardiomyopathy MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hypertonia MetaADEDB
Hypertonic Bladder MetaADEDB
Hypokalaemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypothyroid MetaADEDB
Hypovitaminosis MetaADEDB
Hypoxia MetaADEDB
Immune System Disorder MetaADEDB
Impaired Driving Ability MetaADEDB
Impaired Work Ability MetaADEDB
Impingement Syndrome MetaADEDB
Implantable Defibrillator Insertion MetaADEDB
Impulse-Control Disorder MetaADEDB
Incision Site Complication MetaADEDB
Incontinence MetaADEDB
Infection ADReCS
Infection Urinary Tract MetaADEDB
Influenza ADReCS
Influenza Like Illness ADReCS
Inguinal Hernia Obstructive MetaADEDB
Injection Site Induration MetaADEDB
Insulin Resistance MetaADEDB
Intention Tremor MetaADEDB
Interstitial Lung Disease ADReCS
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intervertebral Disc Space Narrowing MetaADEDB
Intestinal Haemorrhage MetaADEDB
Intestinal Obstruction MetaADEDB
Intrinsic Factor Antibody Negative MetaADEDB
Ischaemia MetaADEDB
Joint Injury MetaADEDB
Joint Lock MetaADEDB
Joint Sprain MetaADEDB
Klebsiella Infection MetaADEDB
Laryngospasm MetaADEDB
Lethargy MetaADEDB
Leukopenia ADReCS
Lice Infestation MetaADEDB
Ligament Calcification MetaADEDB
Limb Discomfort MetaADEDB
Limb Injury MetaADEDB
Lip Dry MetaADEDB
Localised Infection MetaADEDB
Loss Of Weight MetaADEDB
Lower Limb Fracture MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lung Edema MetaADEDB
Macula Lutea Degeneration MetaADEDB
Major Depression MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Marital Problem MetaADEDB
Mastication Disorder MetaADEDB
Mastoiditis MetaADEDB
Medical Device Complication MetaADEDB
Medical Device Implantation MetaADEDB
Memory Impairment ADReCS
Meningioma MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Acidosis MetaADEDB
Metaplasia MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Thyroid MetaADEDB
Micturition Urgency MetaADEDB
Migraine MetaADEDB
Mitral Valve Disease MetaADEDB
Mitral Valve Prolapse MetaADEDB
Mitral Valve Replacement MetaADEDB
Movement Disorder MetaADEDB
Multiple Injuries MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain MetaADEDB
Myelodysplasia MetaADEDB
Myopathy Steroid MetaADEDB
Nasal Congestion MetaADEDB
Nasal Septum Deviation MetaADEDB
Nausea ADReCS
Nephrolithiasis MetaADEDB
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutropenia ADReCS
Nocturia MetaADEDB
Nosocomial Infection MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Off Label Use MetaADEDB
Oliguria MetaADEDB
Oophorectomy MetaADEDB
Open Reduction Of Fracture MetaADEDB
Optic Neuritis MetaADEDB
Oral Discomfort MetaADEDB
Oral Intake Reduced MetaADEDB
Orthopnea MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Osteoporosis MetaADEDB
Ovarian Cancer Metastatic MetaADEDB
Overweight MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palmar Erythema MetaADEDB
Palpitations ADReCS
Pancreatitis MetaADEDB
Paranasal Sinus Hypersecretion MetaADEDB
Parathyroid Tumour MetaADEDB
Parkinson MetaADEDB
Patella Fracture MetaADEDB
Peptic Ulcer Haemorrhage MetaADEDB
Periorbital Haematoma MetaADEDB
Peripheral Artery Aneurysm MetaADEDB
Petechia MetaADEDB
Pharyngeal Disorder MetaADEDB
Pleural Disorder MetaADEDB
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pneumonia Cytomegaloviral MetaADEDB
Pneumonia Fungal MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumothorax MetaADEDB
Pollakiuria MetaADEDB
Polymyalgia Rheumatica MetaADEDB
Polyp MetaADEDB
Portal Vein Occlusion MetaADEDB
Post Procedural Complication MetaADEDB
Postoperative Wound Complication MetaADEDB
Posture Abnormal MetaADEDB
Productive Cough MetaADEDB
Progressive Supranuclear Palsy MetaADEDB
Prostate Infection MetaADEDB
Prostatic Disorder MetaADEDB
Protein Total Increased MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Protrusion Tongue MetaADEDB
Pruritus ADReCS
Psychoses MetaADEDB
Pulmonary Mass MetaADEDB
Pyrexia ADReCS
Radical Mastectomy MetaADEDB
Rectal Cancer Metastatic MetaADEDB
Rectal Ulcer MetaADEDB
Refusal Of Treatment By Relative MetaADEDB
Renal Cyst MetaADEDB
Renal Function Test Abnormal MetaADEDB
Respiratory Failure MetaADEDB
Rhagades MetaADEDB
Rheumatoid Lung MetaADEDB
Rib Fracture MetaADEDB
Road Traffic Accident MetaADEDB
Salivary Gland Inflammation MetaADEDB
Sciatic Nerve Neuropathy MetaADEDB
Scleroderma MetaADEDB
Seborrhoeic Keratosis MetaADEDB
Sepsis ADReCS
Sepsis Syndrome MetaADEDB
Sinus Disorder MetaADEDB
Sinusitis ADReCS
Skin Laceration MetaADEDB
Sleep Apnea MetaADEDB
Sleep Disorder MetaADEDB
Somnolence ADReCS
Speech Disorder MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Fracture MetaADEDB
Spinal Osteoarthritis MetaADEDB
Staphylococcal Infection MetaADEDB
Staring MetaADEDB
Stent Occlusion MetaADEDB
Stent Placement MetaADEDB
Stomatitis ADReCS
Subclavian Vein Thrombosis MetaADEDB
Submandibular Mass MetaADEDB
Surgery MetaADEDB
Syncope Vasovagal MetaADEDB
Synovial Cyst MetaADEDB
Syphilis MetaADEDB
Tachycardia ADReCS
Terminal Dribbling MetaADEDB
Thrombocytopenia ADReCS
Tooth Discolouration MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Infection MetaADEDB
Transient Ischaemic Attack MetaADEDB
Treatment Noncompliance MetaADEDB
Ulcer Haemorrhage MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Limb Fracture MetaADEDB
Urge Incontinence MetaADEDB
Urinary Retention ADReCS
Urinary Tract Infection ADReCS
Urosepsis MetaADEDB
Uterine Bleeding MetaADEDB
Vaginal Disorder MetaADEDB
Vascular Dementia MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertigo ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vitamin B 12 Deficiency MetaADEDB
Vitamin B12 Abnormal MetaADEDB
Vomiting ADReCS
Vulvovaginal Dryness MetaADEDB
Vulvovaginal Mycotic Infection MetaADEDB
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS
Wheelchair User MetaADEDB
Wound MetaADEDB
Wound Infection MetaADEDB
Xanthelasma MetaADEDB
Xerophthalmia ADReCS

InAADR: Drug-Protein-ADRs database