InAADR

Drug Information

Drug Name: Phentermine (122-09-8)
PubChem ID: 4771
SMILES: CC(C)(CC1=CC=CC=C1)N
InchiKey: DHHVAGZRUROJKS-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Anti-Obesity Agents, Appetite Depressants, Autonomic Agents, Central Nervous System Agents, Central Nervous System Stimulants, Neurotransmitter Agents, Peripheral Nervous System Agents, Sympathomimetics

Computed Drug Properties

Molecular Weight (dalton): 149.237
LogP: 1.9664
Ring Count: 1
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 26.02

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Dexfenfluramine (3239-44-9) Cardiac Valve Disease Additive Not Clear Valvular Heart Disease Associated with Fenfluramine–Phentermine

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Dreams MetaADEDB
Abnormal Ecg MetaADEDB
Abnormal Faeces MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Mammogram MetaADEDB
Abscess MetaADEDB
Abuse MetaADEDB
Accident MetaADEDB
Accidental Death MetaADEDB
Accidental Overdose MetaADEDB
Aching Joints MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenopathy MetaADEDB
Administration Site Pain MetaADEDB
Adnexitis MetaADEDB
Adrenal Insufficiency MetaADEDB
Adrenal Neoplasm MetaADEDB
Adverse Drug Effect MetaADEDB
Adverse Event MetaADEDB
Affective Disorder MetaADEDB
Ageusia MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Alcoholism MetaADEDB
Allergies MetaADEDB
Alopecia MetaADEDB
Amnesia MetaADEDB
Anaemia MetaADEDB
Anaemia Of Malignant Disease MetaADEDB
Anaemia Postoperative MetaADEDB
Anaesthesia MetaADEDB
Anal Fissure MetaADEDB
Analgesia MetaADEDB
Aneurysm MetaADEDB
Aneurysm Ruptured MetaADEDB
Angina Unstable MetaADEDB
Anisocoria MetaADEDB
Ankle Fracture MetaADEDB
Anorectal Disorder MetaADEDB
Anorexia MetaADEDB
Anosmia MetaADEDB
Antinuclear Antibody MetaADEDB
Antiphospholipid Syndrome MetaADEDB
Anxiety MetaADEDB
Anxiety Disorders MetaADEDB
Aortic Stenosis MetaADEDB
Aortic Valve Insufficiency MetaADEDB
Apathy MetaADEDB
Arrhythmia MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stenosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthritis MetaADEDB
Arthritis Bacterial MetaADEDB
Arthritis Rheumatoid MetaADEDB
Arthropathy MetaADEDB
Asthenia MetaADEDB
Asthma MetaADEDB
Atelectasis MetaADEDB
Athetosis MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Flutter MetaADEDB
Atrial Tachycardia MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Aura MetaADEDB
Back Ache MetaADEDB
Basal Cell Carcinoma MetaADEDB
Basedow Disease MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Dyskinesia MetaADEDB
Binge-Eating Disorder MetaADEDB
Biopsy Breast MetaADEDB
Bipolar Disorder MetaADEDB
Blood Bicarbonate Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Homocysteine MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Pressure Immeasurable MetaADEDB
Blood Pressure Increased ADReCS
Blood Pressure Systolic Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blurred Vision MetaADEDB
Body Height Decreased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Pain MetaADEDB
Bradycardia MetaADEDB
Bradypnoea MetaADEDB
Brain Concussion MetaADEDB
Brain Death MetaADEDB
Breast Calcifications MetaADEDB
Breast Cancer In Situ MetaADEDB
Breast Cellulitis MetaADEDB
Breast Cyst MetaADEDB
Breast Cyst Excision MetaADEDB
Breast Disorder Female MetaADEDB
Breast Fibrosis MetaADEDB
Breast Lump MetaADEDB
Breast Lump Removal MetaADEDB
Breast Oedema MetaADEDB
Breast Reconstruction MetaADEDB
Breast Tenderness MetaADEDB
Bronchitis MetaADEDB
Bruise MetaADEDB
Bruxism MetaADEDB
Bulimia MetaADEDB
Bullous Lung Disease MetaADEDB
Bundle Branch Block Right MetaADEDB
Bursitis MetaADEDB
Buttock Pain MetaADEDB
Caesarean Section MetaADEDB
Calculus Urinary MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Disorder ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Enzymes Increased MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Valve Disease ADReCS
Cardiac Valve Rupture MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiomyopathy Restrictive MetaADEDB
Carotid Artery Stenosis MetaADEDB
Carpal Tunnel MetaADEDB
Carpal Tunnel Decompression MetaADEDB
Cartilage Development Disorder MetaADEDB
Cellulitis MetaADEDB
Central Nervous System Stimulation ADReCS
Central Venous Catheterisation MetaADEDB
Cerebral Hemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Infarction MetaADEDB
Cervicalgia MetaADEDB
Cervix Carcinoma Recurrent MetaADEDB
Chest Injury MetaADEDB
Chest Pain MetaADEDB
Chill MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Cholecystitis Acute MetaADEDB
Cholecystitis Chronic MetaADEDB
Chorioamnionitis MetaADEDB
Chromaturia MetaADEDB
Chronic Active Hepatitis MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cognition Disorders MetaADEDB
Color Blindness MetaADEDB
Coma MetaADEDB
Completed Suicide MetaADEDB
Compression Fracture MetaADEDB
Compulsive Shopping MetaADEDB
Confusion MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Conjunctival Disorder MetaADEDB
Constipation ADReCS
Cramp MetaADEDB
Crying MetaADEDB
Culture Positive MetaADEDB
Culture Wound Positive MetaADEDB
Cutaneous Ulcer MetaADEDB
Cyst MetaADEDB
Dark Circles Under Eyes MetaADEDB
Deafness MetaADEDB
Deafness Congenital MetaADEDB
Death MetaADEDB
Decreased Activity MetaADEDB
Decreased Libido MetaADEDB
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dependence MetaADEDB
Depressive Disorder MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Retinopathy MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Difficulty In Walking MetaADEDB
Dilatation Ventricular MetaADEDB
Disorder Lung MetaADEDB
Disorder Of Globe MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Disorder Retinal MetaADEDB
Diverticulum Intestinal Haemorrhagic MetaADEDB
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Abuse ADReCS
Drug Abuser MetaADEDB
Drug Addict MetaADEDB
Drug Dispensing Error MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Ineffective MetaADEDB
Drug Screen MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Mouth ADReCS
Duodenal Polyp MetaADEDB
Dysgeusia ADReCS
Dysmenorrhea MetaADEDB
Dysphemia MetaADEDB
Dysphoria ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea At Rest MetaADEDB
Dysstasia MetaADEDB
Dysthymic Disorder MetaADEDB
Dystrophic Calcification MetaADEDB
Dysuria MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Ecchymoses MetaADEDB
Economic Problem MetaADEDB
Ectopic Pregnancies MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram St Segment Abnormal MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Embolism Pulmonary MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Endomyocardial Fibrosis MetaADEDB
Erectile Dysfunction ADReCS
Eruption MetaADEDB
Erythema MetaADEDB
Essential Hypertension MetaADEDB
Euphoric Mood ADReCS
Exanthema MetaADEDB
Exercise Lack Of MetaADEDB
Extrasystoles Ventricular MetaADEDB
Extremity Pain MetaADEDB
Eye Swelling MetaADEDB
Facet Joint Syndrome MetaADEDB
Facial Flushing MetaADEDB
Facial Neuralgia MetaADEDB
Facial Spasm MetaADEDB
Faeces Pale MetaADEDB
Fallopian Tube Operation MetaADEDB
Fat Necrosis MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Fear Of Death MetaADEDB
Feeling Abnormal MetaADEDB
Feeling Drunk MetaADEDB
Fibrinolysis Increased MetaADEDB
Fibrous Histiocytoma MetaADEDB
Fibula Fracture MetaADEDB
Finger Amputation MetaADEDB
Fluid Overload MetaADEDB
Formication MetaADEDB
Fungal Disease MetaADEDB
Gall Bladder MetaADEDB
Gallbladder Cholesterolosis MetaADEDB
Gastric Hypomotility MetaADEDB
Gastroduodenal Ulcer MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Infection MetaADEDB
Gastrooesophageal Reflux Prophylaxis MetaADEDB
Gestational Diabetes MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Goiter MetaADEDB
Granulocytosis MetaADEDB
Granuloma MetaADEDB
Gun Shot Wound MetaADEDB
Haemangioma Of Skin MetaADEDB
Haemochromatosis MetaADEDB
Hair Texture Abnormal MetaADEDB
Hallucinations MetaADEDB
Hand Fracture MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heart Attack MetaADEDB
Heart Failure MetaADEDB
Heart Rate Abnormal MetaADEDB
Heart Valve Diseases MetaADEDB
Hemicephalalgia MetaADEDB
Hemiparesis MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Lesion MetaADEDB
Hepatitis A Antibody MetaADEDB
Hepatitis C MetaADEDB
Hernia Repair MetaADEDB
Herpes Zoster MetaADEDB
Hip Arthroplasty MetaADEDB
Hodgkin Disease MetaADEDB
Hodgkin Disease Recurrent MetaADEDB
Hodgkin Disease Stage Iv MetaADEDB
Hyperalimentation MetaADEDB
Hyperhidrosis MetaADEDB
Hyperinsulinaemia MetaADEDB
Hyperlipaemia MetaADEDB
Hyperplastic Cholecystopathy MetaADEDB
Hypertension MetaADEDB
Hypertension Pulmonary MetaADEDB
Hypoaesthesia MetaADEDB
Hypoaesthesia Oral MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypokalaemia MetaADEDB
Hypotension MetaADEDB
Hypothyroid MetaADEDB
Hysterectomy MetaADEDB
Ill-Defined Disorder MetaADEDB
Impaired Driving Ability MetaADEDB
Impingement Syndrome MetaADEDB
Impotence ADReCS
Incision Site Complication MetaADEDB
Incisional Hernia MetaADEDB
Incorrect Dose Administered MetaADEDB
Increased Appetite MetaADEDB
Increased Bronchial Secretion MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infantile Spasms MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Viral MetaADEDB
Infrequent Bowel Movements MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Warmth MetaADEDB
Insomnia ADReCS
Insulin Resistance MetaADEDB
Intention Tremor MetaADEDB
Intentional Drug Misuse MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Iodine Allergy MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Iron Metabolism Disorder MetaADEDB
Ischaemic Cardiomyopathy ADReCS
Jaw Operation MetaADEDB
Joint Effusion MetaADEDB
Joint Injury MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Kidney Failure MetaADEDB
Kidney Infection MetaADEDB
Kidney Malformation MetaADEDB
Knee Arthroplasty MetaADEDB
Lacrimation Increased MetaADEDB
Laxative Abuse MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Legal Problem MetaADEDB
Lethargy MetaADEDB
Libido Disorder ADReCS
Ligament Sprain MetaADEDB
Limb Injury MetaADEDB
Livedo Reticularis MetaADEDB
Loss Of Weight MetaADEDB
Low Cardiac Output Syndrome MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lower Limb Fracture MetaADEDB
Lumbar Radiculopathy MetaADEDB
Lung Consolidation MetaADEDB
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Lymphedema MetaADEDB
Major Depression MetaADEDB
Marital Problem MetaADEDB
Maxillofacial Operation MetaADEDB
Medical Device Complication MetaADEDB
Medication Tampering MetaADEDB
Memory Disorders MetaADEDB
Meniscus Lesion MetaADEDB
Mental Disorder MetaADEDB
Metabolic Acidosis MetaADEDB
Metabolic Syndrome MetaADEDB
Metastatic Neoplasm MetaADEDB
Microlithiasis MetaADEDB
Middle Ear Inflammation MetaADEDB
Migraine Disorders MetaADEDB
Mitral Valve Disease MetaADEDB
Mitral Valve Insufficiency MetaADEDB
Mitral Valve Prolapse MetaADEDB
Mitral Valve Stenosis MetaADEDB
Mononeuritis MetaADEDB
Movement Disorder MetaADEDB
Mucosal Erosion MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Injuries MetaADEDB
Murphy Sign Positive MetaADEDB
Muscle Injury MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Myocardial Infarction MetaADEDB
Nail Disorder MetaADEDB
Nausea MetaADEDB
Negativism MetaADEDB
Neonatal Respiratory Distress Syndrome MetaADEDB
Nephritic Syndrome MetaADEDB
Nephritis Interstitial MetaADEDB
Nervous Tension MetaADEDB
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
No Adverse Drug Effect MetaADEDB
Nocturnal Dyspnoea MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Obesity MetaADEDB
Obsessive-Compulsive Disorder MetaADEDB
Ocular Icterus MetaADEDB
Oligohydramnios MetaADEDB
Onychophagia MetaADEDB
Optic Disc Haemorrhage MetaADEDB
Optic Neuropathy Ischemic MetaADEDB
Oral Mucosal Blistering MetaADEDB
Oral Soft Tissue Disorder MetaADEDB
Orgasm Abnormal MetaADEDB
Osteoarthritis MetaADEDB
Osteopenia MetaADEDB
Osteosclerosis MetaADEDB
Ovarian Mass MetaADEDB
Overweight MetaADEDB
Pain MetaADEDB
Pain In Throat MetaADEDB
Palpitation MetaADEDB
Palpitations ADReCS
Pancreatitis MetaADEDB
Panic Disorder MetaADEDB
Paraesthesia Oral MetaADEDB
Paranoid Disorders MetaADEDB
Paraparesis MetaADEDB
Paronychia MetaADEDB
Partner Stress MetaADEDB
Pericardial Disease MetaADEDB
Pericardial Effusion MetaADEDB
Pericarditis MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharmaceutical Product Counterfeit MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Phlebothrombosis MetaADEDB
Placental Disorder MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumothorax MetaADEDB
Polysubstance Dependence MetaADEDB
Portal Vein Thrombosis MetaADEDB
Primary Pulmonary Hypertension SIDER
Prothrombin Time Prolonged MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorder ADReCS
Psychotic Episode SIDER
Pulmonary Arrest MetaADEDB
Pulmonary Arterial Hypertension ADReCS
Pulmonary Congestion MetaADEDB
Pulmonary Hypertension ADReCS
Pulmonary Valve Insufficiency MetaADEDB
Pyoderma Gangrenosum MetaADEDB
Radicular Syndrome MetaADEDB
Radiotherapy MetaADEDB
Rash Generalised MetaADEDB
Rectal Discharge MetaADEDB
Renal Lipomatosis MetaADEDB
Renal Tubular Acidosis MetaADEDB
Renal Vein Thrombosis MetaADEDB
Restlessness ADReCS
Retrocollis MetaADEDB
Rib Fracture MetaADEDB
Right Atrial Dilatation MetaADEDB
Road Traffic Accident MetaADEDB
Sarcoidosis MetaADEDB
Scan Lymph Nodes MetaADEDB
Scar MetaADEDB
Schizophrenia MetaADEDB
Scoliosis MetaADEDB
Sensation Of Heaviness MetaADEDB
Sepsis Syndrome MetaADEDB
Serositis MetaADEDB
Sinusitis MetaADEDB
Skeletal Injury MetaADEDB
Sleep Apnea MetaADEDB
Sleep Initiation And Maintenance Disorders MetaADEDB
Sleep Talking MetaADEDB
Sleep Walking MetaADEDB
Social Phobia MetaADEDB
Social Problem MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal Fracture MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spleen Disorder MetaADEDB
Spondylolisthesis MetaADEDB
Spondylosis MetaADEDB
Sternal Fracture MetaADEDB
Streptococcal Bacteraemia MetaADEDB
Stress MetaADEDB
Swollen Tongue MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tendinitis MetaADEDB
Tendon Injury MetaADEDB
Therapeutic Response Unexpected MetaADEDB
Thyroid Neoplasia MetaADEDB
Tibia Fracture MetaADEDB
Tongue Discolouration MetaADEDB
Treatment Noncompliance MetaADEDB
Tremor ADReCS
Tricuspid Valve Disease MetaADEDB
Tricuspid Valve Insufficiency MetaADEDB
Trigonitis MetaADEDB
Ulcer MetaADEDB
Umbilical Cord Abnormality MetaADEDB
Upper Limb Fracture MetaADEDB
Urethral Disorder MetaADEDB
Urinary Tract Disorder MetaADEDB
Urination Disorders MetaADEDB
Urticaria ADReCS
Vanishing Bile Duct Syndrome MetaADEDB
Varicose Vein MetaADEDB
Vascular Diseases MetaADEDB
Venous Thrombosis Limb MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Hypokinesia MetaADEDB
Visual Disturbance MetaADEDB
Vulval Disorder MetaADEDB
Weight Fluctuation MetaADEDB
Weight Gain MetaADEDB
Withdrawal Syndrome ADReCS
Wound MetaADEDB
Wound Infection Staphylococcal MetaADEDB
Wound Secretion MetaADEDB
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database