InAADR

Drug Information

Drug Name: vorozole (118949-22-7)
PubChem ID: 60796
SMILES: CN1C2=C(C=CC(=C2)C(C3=CC=C(C=C3)Cl)N4C=NC=N4)N=N1
InchiKey: XLMPPFTZALNBFS-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 324.775
LogP: 2.8509
Ring Count: 4
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 61.42

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Cardiovascular Disease Adenylate kinase (P00568) Total suppression of aromatase by vorozole may have adverse effects of cardiovascular disease. [ ADR Type 1 ] Aromatase inhibitors as potential cancer chemopreventives
Osteoporosis Adenylate kinase (P00568) Total suppression of aromatase by vorozole may have adverse effects of increased osteoporosis. [ ADR Type 1 ] Aromatase inhibitors as potential cancer chemopreventives
Urogenital Atrophy Adenylate kinase (P00568) Total suppression of aromatase by vorozole may have adverse effects of urogenital atrophy [ ADR Type 1 ] Aromatase inhibitors as potential cancer chemopreventives

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database