| Drug Name: | SIlica (112945-52-5) |
|---|---|
| PubChem ID: | 24261 |
| SMILES: | O=[Si]=O |
| InchiKey: | VYPSYNLAJGMNEJ-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 60.084 |
| LogP | : | -0.6184 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 34.14 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Pulmonary Inflammation | Nuclear factor NF-kappa-B (P19838) | NF-kappa B activation was measurable at 3 h postinstillation of silica@ and this activation continued throughout the 18-h time course@which is associated with silica-induced pulmonary inflammation [ ADR Type 5 ] | Silica-induced pulmonary inflammation in rats: activation of NF-kappa B and its suppression by dexamethasone |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category
| Toxicity | Source |
|---|