| Drug Name: | Remacemide (111686-79-4) |
|---|---|
| PubChem ID: | 60510 |
| SMILES: | CC(CC1=CC=CC=C1)(C2=CC=CC=C2)NC(=O)CN.Cl |
| InchiKey: | HYQMIUSWZXGTCC-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 304.821 |
| LogP | : | 2.6412 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 55.12 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Carbamazepine (298-46-4) | Raise Serum Carbamazepine Levels | Synergistic | Not fully understood, but in vitro studies indicate that remacemide inhibits the cytochrome P450 isoenzyme CYP3A4 | Adjustment of carbamazepine dose to offset the effects of the interaction with remacemide hydrochloride in a double-blind, multicentre, add-on drug trial (CR2237) in refractory epileps |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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