InAADR

Drug Information

Drug Name: Sparfloxacin (110871-86-8)
PubChem ID: 60464
SMILES: C[C@@H]1CN(C[C@@H](N1)C)C2=C(C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(=O)O)F
InchiKey: DZZWHBIBMUVIIW-DTORHVGOSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 392.406
LogP: 2.0816
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 100.59

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Amiodarone (1951-25-3) Torsade De Pointes Additive Not established Overview of electrocardiographic and cardiovascular safety data for sparfloxacin Sparfloxacin Safety Group
Terfenadine (50679-08-8) Torsade De Pointes Additives Additive effect of drug The effect of terfenadine on the cardiac pharmacodynamics of sparfloxacin

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database