InAADR

Drug Information

Drug Name: human insulin (11061-68-0)
PubChem ID: 118984375
SMILES: CC[C@H](C)[C@H]1C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(
InchiKey: PBGKTOXHQIOBKM-FHFVDXKLSA-N
Therapeutic Category:

Computed Drug Properties

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Hypoglycemia Vasopressin V1a receptor (P37288) Increase by naloxone of arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia in obese men [ ADR Type 1 ] Increase by naloxone of arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia in obese men
Meiotic Maturation Ribosomal protein S6 kinase (Q15418) Insulin elicited an early (20-30 min) 3-fold stimulation of S6 peptide phosphorylating activity@a common S6 peptide kinase is activated as a consequence of short and long term insulin exposure@which greatly facilitate insulin-induced meiotic maturation [ ADR Type 1 ] Insulin and progesterone activate a common synthetic ribosomal protein S6 peptide kinase in Xenopus oocytes

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abnormal Behaviour ADReCS
Abscess ADReCS
Acne ADReCS
Acute Coronary Syndrome ADReCS
Affect Lability ADReCS
Agitation ADReCS
Albuminuria ADReCS
Alopecia ADReCS
Amenorrhoea ADReCS
Anaemia ADReCS
Anaphylactic Reaction PROTECT
Anaphylactic Shock ADReCS
Aneurysm ADReCS
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anorectal Disorder ADReCS
Anorexia ADReCS
Anti-Insulin Antibody PROTECT
Anxiety ADReCS
Appetite Absent SIDER
Arterial Disorder ADReCS
Arthralgia ADReCS
Arthritis ADReCS
Arthropathy ADReCS
Asthenia ADReCS
Asthma ADReCS
Atrioventricular Block ADReCS
Back Pain ADReCS
Balance Disorder ADReCS
Biliary Colic ADReCS
Bladder Pain ADReCS
Blindness ADReCS
Blister ADReCS
Block Heart SIDER
Blood Glucose Increased ADReCS
Blood Pressure Decreased ADReCS
Body Temperature Increased ADReCS
Bone Pain ADReCS
Bradycardia ADReCS
Brain Injury ADReCS
Breast Feeding ADReCS
Bronchitis ADReCS
Bronchospasm PROTECT
Bullous Eruption ADReCS
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Murmur ADReCS
Cardiomyopathy ADReCS
Cardiovascular Disorder ADReCS
Carpal Tunnel Syndrome ADReCS
Cellulitis ADReCS
Cerebration Impaired SIDER
Chest Pain ADReCS
Coagulopathy SIDER
Cold Sweat ADReCS
Colitis ADReCS
Collagen Disorder SIDER
Common Wart SIDER
Confusional State ADReCS
Congenital Eye Disorder SIDER
Conjunctivitis ADReCS
Constipation ADReCS
Convulsion ADReCS
Coronary Artery Disease ADReCS
Cough ADReCS
Cough Decreased ADReCS
Cough Increased ADReCS
Cyst ADReCS
Cystitis ADReCS
Cystitis Noninfective ADReCS
Death ADReCS
Decreased Appetite ADReCS
Dental Caries ADReCS
Depressed Mood ADReCS
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Dermatitis Contact ADReCS
Diabetic Autonomic Neuropathy ADReCS
Diabetic Ketoacidosis ADReCS
Diabetic Neuropathy ADReCS
Diabetic Retinopathy ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Disease Progression ADReCS
Disequilibrium Syndrome SIDER
Disorientation ADReCS
Disturbance In Attention ADReCS
Dizziness ADReCS
Drug Hypersensitivity ADReCS
Dry Mouth ADReCS
Dry Skin ADReCS
Dysarthria ADReCS
Dysgeusia ADReCS
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphonia ADReCS
Dyspnoea ADReCS
Ear Disorder ADReCS
Ear Infection ADReCS
Ear Pain ADReCS
Eczema ADReCS
Emotional Distress ADReCS
Epistaxis ADReCS
Eruption Lichenoid SIDER
Erythema ADReCS
Eye Haemorrhage ADReCS
Eye Infection ADReCS
Eye Pain ADReCS
Face Oedema ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Flushing ADReCS
Gastritis ADReCS
Gastroenteritis ADReCS
Gastrointestinal Disorder ADReCS
Gastrointestinal Pain ADReCS
Gastrointestinal Tract Irritation ADReCS
Gastrooesophageal Reflux Disease ADReCS
Gingivitis ADReCS
Glucose Increased SIDER
Glycosuria ADReCS
Goitre ADReCS
Gout ADReCS
Haematoma ADReCS
Haematuria ADReCS
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhoids ADReCS
Headache ADReCS
Heart Rate Increased ADReCS
Hot Flush ADReCS
Hunger ADReCS
Hyperaesthesia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hyperkinesia ADReCS
Hyperlipidaemia ADReCS
Hypernatraemia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hyperthyroidism ADReCS
Hypertonia ADReCS
Hypertrophy ADReCS
Hypochromic Anaemia ADReCS
Hypoglycaemia ADReCS
Hypoglycaemic Coma ADReCS
Hypoglycaemic Episode SIDER
Hypoglycaemic Seizure SIDER
Hypoglycemic Reaction SIDER
Hypokalaemia ADReCS
Hyporeflexia ADReCS
Hypotension ADReCS
Hypothyroidism ADReCS
Ill-Defined Disorder ADReCS
Immobile ADReCS
Immune System Disorder SIDER
Increased Bronchial Secretion ADReCS
Infarction ADReCS
Infection ADReCS
Infection Parasitic ADReCS
Inflammation ADReCS
Influenza ADReCS
Injection Site Bruising PROTECT
Injection Site Erythema PROTECT
Injection Site Haematoma ADReCS
Injection Site Inflammation ADReCS
Injection Site Pain ADReCS
Injection Site Pruritus PROTECT
Injection Site Reaction ADReCS
Injection Site Swelling PROTECT
Injection Site Urticaria PROTECT
Insulin Allergy SIDER
Intestinal Functional Disorder ADReCS
Irritability ADReCS
Irritable Bowel Syndrome ADReCS
Keratitis ADReCS
Ketoacidosis ADReCS
Ketosis ADReCS
Laryngitis ADReCS
Left Ventricular Failure ADReCS
Lichenoid Keratosis ADReCS
Lightheadedness SIDER
Lipoatrophy ADReCS
Lipodystrophy ADReCS
Lipodystrophy Acquired ADReCS
Lipohypertrophy ADReCS
Lipoma ADReCS
Loss Of Consciousness ADReCS
Lymphadenopathy ADReCS
Lymphoma ADReCS
Malaise ADReCS
Mass ADReCS
Mastitis ADReCS
Menopausal Symptoms ADReCS
Menorrhagia ADReCS
Mental Disability ADReCS
Migraine ADReCS
Mood Swings ADReCS
Motion Sickness ADReCS
Mucosal Inflammation ADReCS
Muscle Rigidity ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Myocardial Infarction ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Stiffness ADReCS
Neoplasm ADReCS
Nervousness ADReCS
Neuralgia ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Nuchal Rigidity ADReCS
Obstruction ADReCS
Oedema ADReCS
Oedema Mouth ADReCS
Oedema Peripheral ADReCS
Onychomycosis ADReCS
Osteoarthritis ADReCS
Osteoarthropathy SIDER
Osteoporosis ADReCS
Otitis Externa ADReCS
Otitis Media ADReCS
Ovarian Cyst ADReCS
Pain ADReCS
Pale SIDER
Pallor ADReCS
Pallor Of Skin SIDER
Palpitations ADReCS
Paraesthesia ADReCS
Paraesthesia Oral ADReCS
Paralysis ADReCS
Personality Change ADReCS
Pharyngitis ADReCS
Phlebitis ADReCS
Photosensitivity Reaction ADReCS
Pilonidal Cyst ADReCS
Pneumonia ADReCS
Pollakiuria ADReCS
Polyuria ADReCS
Premenstrual Syndrome ADReCS
Premenstrual Tension SIDER
Pruritus ADReCS
Pulmonary Oedema ADReCS
Pulse Abnormal ADReCS
Pulse Pressure Decreased ADReCS
Purpura ADReCS
Rash ADReCS
Rash Generalised ADReCS
Rectal Haemorrhage ADReCS
Refraction Disorder ADReCS
Renal Pain ADReCS
Respiratory Disorder ADReCS
Respiratory Tract Infection ADReCS
Restlessness ADReCS
Retinal Disorder ADReCS
Retinal Haemorrhage ADReCS
Retinopathy Proliferative PROTECT
Retrosternal Pain SIDER
Rheumatoid Arthritis ADReCS
Rhinitis ADReCS
Sciatica ADReCS
Serum Sickness ADReCS
Shock ADReCS
Sinusitis ADReCS
Skin Cold Clammy ADReCS
Skin Discolouration ADReCS
Skin Disorder ADReCS
Skin Hypertrophy ADReCS
Skin Papilloma ADReCS
Skin Reaction PROTECT
Skin Ulcer ADReCS
Sleep Disorder ADReCS
Slurred Speech SIDER
Social Avoidant Behaviour ADReCS
Sodium Retention PROTECT
Somnolence ADReCS
Sputum Increased ADReCS
Sticky Skin ADReCS
Sudden Death ADReCS
Swelling ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tendon Disorder ADReCS
Tenosynovitis ADReCS
Tension ADReCS
Thirst ADReCS
Thready Pulse SIDER
Thrombophlebitis ADReCS
Thrombophlebitis Of The Leg SIDER
Thrombosis ADReCS
Thrombosis Leg ADReCS
Tooth Caries Aggravated Nos SIDER
Tooth Disorder ADReCS
Toothache ADReCS
Torticollis ADReCS
Tracheitis ADReCS
Tremor ADReCS
Type I Hypersensitivity PROTECT
Ulcer ADReCS
Ulcerative Keratitis ADReCS
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Urine Abnormality ADReCS
Urine Analysis Abnormal ADReCS
Urine Output Increased ADReCS
Urticaria ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Varicella ADReCS
Vascular Purpura ADReCS
Vein Disorder ADReCS
Vestibular Disorder ADReCS
Viral Infection ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Voice Alteration ADReCS
Voice Disturbance SIDER
Vomiting ADReCS
Weight Decreased ADReCS
Weight Increased ADReCS
Wheezing ADReCS
Withdrawn SIDER
Xerophthalmia ADReCS

InAADR: Drug-Protein-ADRs database