Drug Name: | Pristinamycin (11006-76-1) |
---|---|
PubChem ID: | 11979535 |
SMILES: | CCC1C(=O)N2CCCC2C(=O)N(C(C(=O)N3CCC(=O)CC3C(=O)NC(C(=O)OC(C(C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C.CC1C=CC(=O)NCC=CC(=CC(CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)OC1C(C)C)O)C |
InchiKey: | MVTQIFVKRXBCHS-FHWPYUEJSA-N |
Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents, Enzyme Inhibitors, Protein Synthesis Inhibitors |
Molecular Weight (dalton) | : | 1349.5 |
LogP | : | 3.8634 |
Ring Count | : | 4 |
Hydrogen Bond Acceptor Count | : | 19 |
Hydrogen Bond Donor Count | : | 6 |
Total Polar Surface Area | : | 363.76 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
---|---|---|---|---|
Methotrexate (59-05-2) | Anus Abnormal | Synergistic | Not understood | Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic |
Methotrexate (59-05-2) | Balanitis | Synergistic | Not understood | Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic |
Methotrexate (59-05-2) | Mucositis Oral | Synergistic | Not understood | Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic |
Methotrexate (59-05-2) | Neutropenia | Synergistic | Not understood | Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic |
Methotrexate (59-05-2) | Thrombocytopenia | Synergistic | Not understood | Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
---|
This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
---|
This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
---|
This panel provides information on drug category