| Drug Name: | Mizolastine (108612-45-9) |
|---|---|
| PubChem ID: | 124080940 |
| SMILES: | CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)[O-])CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@H](C(O4)(C)C)OC)OC(=O)N)O.[Na+] |
| InchiKey: | WWPRGAYLRGSOSU-HYAAXHPHSA-M |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 634.614 |
| LogP | : | -0.00088 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 11 |
| Hydrogen Bond Donor Count | : | 4 |
| Total Polar Surface Area | : | 202.84 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Lorazepam (846-49-1) | Amnesia | Synergistic | antihistamines cause sedation, and this would be expected to be increased by some of the benzodiazepines by the simple addition of their CNS depressant effects | Lack of interaction between a new antihistamine, mizolastine, and lorazepam on psychomotor performance and memory in healthy volunteers |
| Lorazepam (846-49-1) | Sedation | Synergistic | antihistamines cause sedation, and this would be expected to be increased by some of the benzodiazepines by the simple addition of their CNS depressant effects | Lack of interaction between a new antihistamine, mizolastine, and lorazepam on psychomotor performance and memory in healthy volunteers |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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