InAADR

Drug Information

Drug Name: benidipine (105979-17-7)
PubChem ID: 656668
SMILES: CC1=C([C@H](C(=C(N1)C)C(=O)O[C@@H]2CCCN(C2)CC3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC
InchiKey: QZVNQOLPLYWLHQ-ZEQKJWHPSA-N
Therapeutic Category: Calcium Channel Blockers, Cardiovascular Agents, Membrane Transport Modulators, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 505.571
LogP: 4.2104
Ring Count: 2
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 111.01

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Neoplasm MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Ecg MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Movements MetaADEDB
Abscess Drainage MetaADEDB
Accelerated Hypertension MetaADEDB
Aching Muscles MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Glomerulonephritis MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Failure MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Abnormal MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Liver Disease MetaADEDB
Allergic Vasculitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Amyloidosis MetaADEDB
Amyotrophy MetaADEDB
Anaesthesia MetaADEDB
Angina MetaADEDB
Angioplasty MetaADEDB
Anorexia MetaADEDB
Aortic Dissection MetaADEDB
Appetite Disorder MetaADEDB
Arteriosclerosis Obliterans MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Decreased MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Atrial Hypertrophy MetaADEDB
Atrioventricular Block Complete MetaADEDB
Attempted Suicide MetaADEDB
Autoimmune Hepatitis MetaADEDB
Av Dissociation MetaADEDB
Azotaemia MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Test Positive MetaADEDB
Bence Jones Protein Urine MetaADEDB
Biliary Dilatation MetaADEDB
Bladder Catheter Temporary MetaADEDB
Bladder Catheterisation MetaADEDB
Bladder Retention MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Immunoglobulin E MetaADEDB
Blood Lactate Dehydrogenase Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Urine Present MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Fibrosis MetaADEDB
Bradycardia MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Stem Haemorrhage MetaADEDB
Brain Stem Infarction MetaADEDB
Bronchial Wall Thickening MetaADEDB
Bulging MetaADEDB
Bundle Branch Block Right MetaADEDB
C-Reactive Protein Increased MetaADEDB
Caesarean Section MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Failure Chronic MetaADEDB
Cardiac Hypertrophy MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiothoracic Ratio Increased MetaADEDB
Cardiovascular Disorder MetaADEDB
Cartilage Development Disorder MetaADEDB
Cell Marker Increased MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Ischaemia MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chromatopsia MetaADEDB
Chronic Kidney Disease MetaADEDB
Circadian Rhythm Sleep Disorder MetaADEDB
Cirrhosis MetaADEDB
Clostridium Colitis MetaADEDB
Colitis Ischaemic MetaADEDB
Completed Suicide MetaADEDB
Condition Aggravated MetaADEDB
Corneal Disorder MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coronary Artery Surgery MetaADEDB
Coughing Blood MetaADEDB
Creatinine Renal Clearance Increased MetaADEDB
Cryptogenic Organising Pneumonia MetaADEDB
Cyanosis MetaADEDB
Cytomegalovirus Antigen MetaADEDB
Deafness MetaADEDB
Decreased Activity MetaADEDB
Decubitus Ulcer MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Device Related Infection MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetic Nephropathy MetaADEDB
Dialysis MetaADEDB
Disease Of Liver MetaADEDB
Disorder Lung MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Disseminated Tuberculosis MetaADEDB
Diverticulitis Intestinal Haemorrhagic MetaADEDB
Diverticulum Intestinal Haemorrhagic MetaADEDB
Dna Antibody Positive MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Duodenitis MetaADEDB
Dysaesthesia MetaADEDB
Dyslalia MetaADEDB
Dysstasia MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram St-T Segment Elevation MetaADEDB
Electrocardiogram T Wave Abnormal MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Elevated Triglycerides MetaADEDB
Emphysema MetaADEDB
Endotoxic Shock MetaADEDB
Endotracheal Intubation MetaADEDB
Enteritis MetaADEDB
Enterocolitis Bacterial MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Fasciitis MetaADEDB
Epistaxis MetaADEDB
Esophageal Ulcer MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eyelid Function Disorder MetaADEDB
Facial Spasm MetaADEDB
Fat Embolism MetaADEDB
Feeding Tube Complication MetaADEDB
Fractured Pelvis Nos MetaADEDB
Gallbladder Oedema MetaADEDB
Gamma-Glutamyltransferase Abnormal MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrectomy MetaADEDB
Gastric Adenoma MetaADEDB
Gastric Perforation MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Sounds Abnormal MetaADEDB
General Physical Condition MetaADEDB
Gingival Erythema MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis Membranoproliferative MetaADEDB
Glucose Intolerance MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Haemodialysis MetaADEDB
Haemophilus Infection MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Haemorrhagic Disorder MetaADEDB
Haemostasis MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Atrophy MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatic Neoplasia MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis MetaADEDB
Hepatitis Fulminant MetaADEDB
Herpes Zoster MetaADEDB
Hiccough MetaADEDB
Hilar Lymphadenopathy MetaADEDB
Hoarseness MetaADEDB
Hypoaesthesia Facial MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypokalaemia MetaADEDB
Hypoproteinaemia MetaADEDB
Hyporeflexia MetaADEDB
Hypothyroid MetaADEDB
Ild MetaADEDB
Ileal Stenosis MetaADEDB
Immunosuppressant Drug Level Decreased MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Viral MetaADEDB
Injection Site Cellulitis MetaADEDB
Injury Asphyxiation MetaADEDB
Interstitial Nephritis MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Lacunar Infarction MetaADEDB
Large Intestine Perforation MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Leucine Aminopeptidase Increased MetaADEDB
Liver Carcinoma Ruptured MetaADEDB
Long Qt Syndrome MetaADEDB
Lung Infiltration MetaADEDB
Lung Injury MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lung Squamous Cell Carcinoma Stage Unspecified MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Lymphocyte Stimulation Test MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Mechanical Ventilation MetaADEDB
Metabolic Acidosis MetaADEDB
Monocyte Percentage Increased MetaADEDB
Monoparesis MetaADEDB
Mood Altered MetaADEDB
Muscle Hypertrophy MetaADEDB
Myocardial Rupture MetaADEDB
Myoglobin Blood Increased MetaADEDB
Myoglobin Urine Present MetaADEDB
Myoglobinaemia MetaADEDB
Nasopharyngitis MetaADEDB
Neonatal Asphyxia MetaADEDB
Neonatal Respiratory Failure MetaADEDB
Nephrotic Syndrome MetaADEDB
Neutrophil Count Decreased MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Ocular Icterus MetaADEDB
Oligohydramnios MetaADEDB
Oliguria MetaADEDB
Organising Pneumonia MetaADEDB
Oropharyngeal Discomfort MetaADEDB
Orthopnea MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pallor MetaADEDB
Pancreatic Cancer MetaADEDB
Pedal Pulse Absent MetaADEDB
Periarthritis MetaADEDB
Peritonitis MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phlebitis MetaADEDB
Photodermatosis MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia Fungal MetaADEDB
Pneumonia Streptococcal MetaADEDB
Po2 Abnormal MetaADEDB
Po2 Decreased MetaADEDB
Polymyositis MetaADEDB
Posture Abnormal MetaADEDB
Primary Hyperaldosteronism MetaADEDB
Primary Sequestrum MetaADEDB
Prinzmetal Angina MetaADEDB
Productive Cough MetaADEDB
Protein Total Decreased MetaADEDB
Pseudoaldosteronism MetaADEDB
Pulmonary Bulla MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Function Test Abnormal MetaADEDB
Pulmonary Hypoplasia MetaADEDB
Pulmonary Thrombosis MetaADEDB
Pyloric Stenosis MetaADEDB
Rectal Ulcer MetaADEDB
Renal Function Test Abnormal MetaADEDB
Renal Graft Loss MetaADEDB
Renal Impairment MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Failure MetaADEDB
Retrocollis MetaADEDB
Rhabdomyolysis MetaADEDB
Sensation Of Heaviness MetaADEDB
Sense Of Oppression MetaADEDB
Sequestrectomy MetaADEDB
Shock Haemorrhagic MetaADEDB
Shunt Malfunction MetaADEDB
Shunt Occlusion MetaADEDB
Speech Disorder MetaADEDB
Spinal Cord Infarction MetaADEDB
Spinal X-Ray MetaADEDB
Sputum Retention MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Tachycardia Ventricular MetaADEDB
Tension Headache MetaADEDB
Thrombotic Microangiopathy MetaADEDB
Tongue Paralysis MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Tracheostomy MetaADEDB
Tumour Necrosis MetaADEDB
Upper Respiratory Tract Inflammation MetaADEDB
Urine Amylase MetaADEDB
Urine Output Increased MetaADEDB
Urobilin Urine Present MetaADEDB
Uterine Cancer MetaADEDB
Vascular Resistance Systemic Decreased MetaADEDB
Venous Aneurysm MetaADEDB
Ventricular Fibrillation MetaADEDB
Volume Blood Decreased MetaADEDB
Water Intoxication MetaADEDB

InAADR: Drug-Protein-ADRs database