InAADR

Drug Information

Drug Name: Daptomycin (103060-53-3)
PubChem ID: 117590581
SMILES: CCCCCCCCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)NC3C(OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)C(C)CC(=O)O)CC(=O)C4=CC=CC=
InchiKey: DOAKLVKFURWEDJ-QBZQMSFSSA-N
Therapeutic Category:

Computed Drug Properties

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Simvastatin (79902-63-9) Increased Risk Of Muscle Toxicity Additive Not understood Severe myopathy and possible hepatotoxicity related to daptomycin

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abscess MetaADEDB
Acute Kidney Injury MetaADEDB
Alanine Aminotransferase Increased ADReCS
Alcoholic Pancreatitis ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angioedema PROTECT
Angiopathy ADReCS
Anxiety ADReCS
Arrhythmia ADReCS
Arrhythmia Supraventricular ADReCS
Arthralgia ADReCS
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Atrial Fibrillation ADReCS
Atrial Flutter ADReCS
Back Pain ADReCS
Bacteremia MetaADEDB
Bacterial Infection ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Bicarbonate Increased ADReCS
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatine Phosphokinase Normal SIDER
Blood Creatinine Increased ADReCS
Blood Lactate Dehydrogenase Abnormal ADReCS
Blood Lactate Dehydrogenase Increased ADReCS
Blood Phosphorus Increased ADReCS
Body Temperature Increased ADReCS
Candida Infection PROTECT
Candidiasis ADReCS
Cardiac Arrest ADReCS
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Fibrillation ADReCS
Cardiac Flutter ADReCS
Cellulitis ADReCS
Chest Pain ADReCS
Chills ADReCS
Cholangitis ADReCS
Clostridium Difficile Colitis PROTECT
Coma ADReCS
Confusional State ADReCS
Constipation ADReCS
Corynebacterium Infections MetaADEDB
Cough ADReCS
Creatine Phosphokinase Normal SIDER
Crohn Disease ADReCS
Death ADReCS
Decreased Appetite ADReCS
Dermatitis ADReCS
Dermatitis Allergic PROTECT
Dermatitis Bullous ADReCS
Device Related Sepsis ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Dizziness ADReCS
Drug Hypersensitivity ADReCS
Drug Reaction With Eosinophilia And Systemic Symptoms PROTECT
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyskinesia ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Eczema ADReCS
Effusion ADReCS
Electrolyte Disturbance SIDER
Electrolyte Imbalance ADReCS
Endocarditis Bacterial MetaADEDB
Eosinophilia ADReCS
Eosinophilic Pneumonia ADReCS
Epigastric Discomfort ADReCS
Erythema ADReCS
Extrasystoles PROTECT
Eye Irritation ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Jittery ADReCS
Flatulence ADReCS
Flushing ADReCS
Fungaemia ADReCS
Fungal Infection ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gingival Pain ADReCS
Glossitis PROTECT
Gram-Positive Bacterial Infections MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Hallucination ADReCS
Headache ADReCS
Heat Rash ADReCS
Hepatic Function Abnormal ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Oral ADReCS
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hypomagnesaemia ADReCS
Hypotension ADReCS
Infarction ADReCS
Infusion Related Reaction PROTECT
Infusion Site Reaction PROTECT
Injection Site Reaction ADReCS
Insomnia ADReCS
International Normalised Ratio Increased ADReCS
Intestinal Infarction ADReCS
Jaundice ADReCS
Kidney Diseases MetaADEDB
Leukocytosis ADReCS
Limb Paresis SIDER
Liver Diseases MetaADEDB
Liver Function Test Abnormal ADReCS
Lymphadenopathy ADReCS
Mediastinitis ADReCS
Meningitis Bacterial MetaADEDB
Mental Status Changes ADReCS
Monoparesis ADReCS
Mucous Membrane Disorder ADReCS
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myoglobin Blood Increased ADReCS
Myopathy ADReCS
Myositis PROTECT
Nausea ADReCS
Nervousness ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oral Candidiasis ADReCS
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Oropharyngeal Swelling PROTECT
Osteomyelitis ADReCS
Pain ADReCS
Pain In Extremity ADReCS
Pancreatitis ADReCS
Paraesthesia ADReCS
Penicillin Allergy SIDER
Peripheral Sensory Neuropathy ADReCS
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pneumonia Staphylococcal MetaADEDB
Protein Urine Present ADReCS
Proteinuria ADReCS
Prothrombin Level Increased ADReCS
Prothrombin Time Prolonged ADReCS
Pruritus ADReCS
Pruritus Generalised ADReCS
Pulmonary Eosinophilia ADReCS
Pyelonephritis MetaADEDB
Pyrexia PROTECT
Rash ADReCS
Rash Pustular ADReCS
Rash Vesicular ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment ADReCS
Respiratory Disorder ADReCS
Rhabdomyolysis ADReCS
Sepsis ADReCS
Serum Bicarbonate Increased SIDER
Shock Septic MetaADEDB
Staphylococcal Bacteraemia ADReCS
Staphylococcal Infections MetaADEDB
Staphylococcus Aureus Bacteremia SIDER
Stomatitis ADReCS
Supraventricular Tachycardia PROTECT
Syncope PROTECT
Tachycardia PROTECT
Tenderness ADReCS
Tension ADReCS
Thrombocytopenia ADReCS
Thrombocytosis ADReCS
Tinnitus ADReCS
Transaminases Increased PROTECT
Tremor PROTECT
Urinary Tract Infection ADReCS
Urinary Tract Infection Fungal ADReCS
Urosepsis ADReCS
Urticaria ADReCS
Vaginal Infection PROTECT
Vertigo ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Mycotic Infection ADReCS
Wheezing PROTECT

InAADR: Drug-Protein-ADRs database