Drug Name: | Cefacetrile (10206-21-0) |
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PubChem ID: | 91562 |
SMILES: | CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CC#N)SC1)C(=O)O |
InchiKey: | RRYMAQUWDLIUPV-BXKDBHETSA-N |
Therapeutic Category: |
Molecular Weight (dalton) | : | 339.329 |
LogP | : | -0.79822 |
Ring Count | : | 0 |
Hydrogen Bond Acceptor Count | : | 7 |
Hydrogen Bond Donor Count | : | 2 |
Total Polar Surface Area | : | 136.8 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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Furosemide (54-31-9) | Nephrotoxicity | Antagonistic | Cefacetrile is nephrotoxic, but why this should be increased by furosemide is not understood. It may possibly be related to a reduction in its clearance | Possible interaction between cephacetrile and frusemide in rabbits and rats |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
Toxicity | Source |
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