InAADR

Drug Information

Drug Name: Pentamidine (100-33-4)
PubChem ID: 4735
SMILES: C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N
InchiKey: XDRYMKDFEDOLFX-UHFFFAOYSA-N
Therapeutic Category: Anti-Infective Agents, Antifungal Agents, Antiparasitic Agents, Antiprotozoal Agents, Trypanocidal Agents

Computed Drug Properties

Molecular Weight (dalton): 340.427
LogP: 2.88284
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 118.2

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Amphotericin B (1397-89-3) Acute Renal Failure Additive Not Understood Acute, rapidly progressive renal failure with simultaneous use of amphotericin B and pentamidine

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp ADReCS
Abdominal Pain ADReCS
Abortion Spontaneous ADReCS
Abscess Oral ADReCS
Abscess Sterile ADReCS
Acanthamoeba Keratitis MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Acidosis MetaADEDB
Acquired Immunodeficiency Syndrome MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Otitis Media MetaADEDB
Acute Pancreatitis MetaADEDB
Adenopathy MetaADEDB
Adenovirus Infection MetaADEDB
Adrenal Neoplasm MetaADEDB
Affect Lability ADReCS
Afib MetaADEDB
Ageusia ADReCS
Aids-Related Opportunistic Infections MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Reaction ADReCS
Allergies MetaADEDB
Amebiasis MetaADEDB
Amnesia ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anemia Hemolytic MetaADEDB
Anemia Megaloblastic MetaADEDB
Angioedema MetaADEDB
Anorexia ADReCS
Anosmia ADReCS
Antidepressant Drug Clearance Decreased MetaADEDB
Anxiety ADReCS
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arthralgia ADReCS
Ascites MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asthenia MetaADEDB
Asthma ADReCS
Atrial Tachycardia MetaADEDB
Atrioventricular Block MetaADEDB
Atypical Mycobacterial Infection MetaADEDB
Autonomic Nervous System Diseases MetaADEDB
Azotaemia ADReCS
Azotemia MetaADEDB
Babesiosis MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Bacteroides Infection MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Bk Virus Infection MetaADEDB
Bladder Disorder MetaADEDB
Blast Cells Present MetaADEDB
Blepharitis ADReCS
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine Increased ADReCS
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Urea Nitrogen Increased ADReCS
Body Temperature Decreased ADReCS
Body Temperature Increased MetaADEDB
Bone Disorder MetaADEDB
Bone Marrow Depression MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Spur MetaADEDB
Bradycardia MetaADEDB
Bradypnoea MetaADEDB
Brain Herniation MetaADEDB
Bronchial Spasm MetaADEDB
Bronchitis ADReCS
Bronchospasm ADReCS
Bruise MetaADEDB
Bulging MetaADEDB
Cachectic MetaADEDB
Candidiasis Of Mouth MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardioactive Drug Level MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiotoxicity MetaADEDB
Cardiovascular Insufficiency ADReCS
Caustic Injury MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cerebrovascular Accident ADReCS
Chapped Lips MetaADEDB
Cheilitis MetaADEDB
Chest Pain ADReCS
Chest Tightness ADReCS
Chills ADReCS
Chloroma MetaADEDB
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Chromosome Abnormality MetaADEDB
Clotting MetaADEDB
Cmv Infection MetaADEDB
Coagulation Time Prolonged ADReCS
Colitis ADReCS
Coma MetaADEDB
Confusional State ADReCS
Conjunctival Hyperaemia MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Contact Lens Intolerance ADReCS
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Coombs Direct Test Positive MetaADEDB
Cough ADReCS
Craniosynostosis MetaADEDB
Cryptogenic Cirrhosis MetaADEDB
Csf Protein MetaADEDB
Cyanosis ADReCS
Cytomegalovirus Chorioretinitis ADReCS
Cytomegalovirus Colitis ADReCS
Cytomegalovirus Enteritis MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Deafness ADReCS
Deafness Bilateral MetaADEDB
Decreased Appetite ADReCS
Deep Vein Thromboses MetaADEDB
Dehydration MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Seborrheic MetaADEDB
Device Related Sepsis ADReCS
Diabetes MetaADEDB
Diabetes Mellitus ADReCS
Diabetes Mellitus Insulin-Dependent MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disease Progression MetaADEDB
Disorder Of Globe MetaADEDB
Disorders Of Lipid Metabolism MetaADEDB
Disseminated Cytomegaloviral Infection MetaADEDB
Disseminated Intravascular Coagulation ADReCS
Dizziness ADReCS
Drug Hypersensitivity MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dry Skin ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysstasia MetaADEDB
Dystonia MetaADEDB
Ear Infection ADReCS
Early Morning Awakening MetaADEDB
Electrocardiogram St Segment Abnormal ADReCS
Electrolyte Disorder MetaADEDB
Encephalitis MetaADEDB
Encephalitis Viral ADReCS
Encephalopathy MetaADEDB
Enlarged Liver MetaADEDB
Eosinophilia ADReCS
Eosinophilic Pneumonia ADReCS
Epstein-Barr Virus Antigen Positive MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Escherichia Infection MetaADEDB
Exanthema MetaADEDB
Eye Pain ADReCS
Eyelid Margin Crusting MetaADEDB
Face Injury MetaADEDB
Face Oedema ADReCS
Facial Dysmorphism MetaADEDB
Factor Viii Deficiency MetaADEDB
Fat Redistribution MetaADEDB
Fatigue ADReCS
Flank Pain ADReCS
Folliculitis MetaADEDB
Gait Disturbance ADReCS
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Polyps MetaADEDB
Gastric Ulcer ADReCS
Gastritis ADReCS
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Mucosal Disorder MetaADEDB
Generalised Erythema MetaADEDB
Gingival Hyperplasia MetaADEDB
Gingivectomy MetaADEDB
Gingivitis ADReCS
Glucose Metabolism Disorders MetaADEDB
Glycosuria MetaADEDB
Gout ADReCS
Graft Versus Host Disease MetaADEDB
Haemarthrosis MetaADEDB
Haematochezia ADReCS
Haematuria ADReCS
Haemolytic Anaemia MetaADEDB
Haemoptysis ADReCS
Hair Texture Abnormal ADReCS
Hallucination ADReCS
Headache ADReCS
Heart Arrest MetaADEDB
Heart Block MetaADEDB
Heart Rate Increased MetaADEDB
Hematologic Diseases MetaADEDB
Hematuria MetaADEDB
Hemianopia ADReCS
Hemoglobinuria MetaADEDB
Hemorrhage MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatomegaly ADReCS
Hepatotoxicity MetaADEDB
Hernia Hiatal MetaADEDB
Herpes Pharyngitis ADReCS
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hiatus Hernia ADReCS
Hiccup MetaADEDB
High Blood Pressure MetaADEDB
Histoplasmosis ADReCS
Hiv Infections MetaADEDB
Hydronephrosis MetaADEDB
Hyperglycaemia ADReCS
Hyperkalaemia ADReCS
Hyperkalemia MetaADEDB
Hyperprolactinaemia MetaADEDB
Hypersensitivity ADReCS
Hypertelorism Of Orbit MetaADEDB
Hypertension ADReCS
Hyperventilation ADReCS
Hypesthesia MetaADEDB
Hypoaesthesia ADReCS
Hypocalcaemia ADReCS
Hypocalcemia MetaADEDB
Hypoglycaemia ADReCS
Hypoglycemia MetaADEDB
Hypomagnesaemia ADReCS
Hypotension ADReCS
Impaired Healing MetaADEDB
Impetigo MetaADEDB
Inappropriate Antidiuretic Hormone Secretion ADReCS
Incontinence ADReCS
Infection ADReCS
Influenza ADReCS
Influenza Like Illness MetaADEDB
Injection Site Extravasation ADReCS
Injection Site Induration ADReCS
Insomnia ADReCS
Interstitial Lung Disease ADReCS
Itch MetaADEDB
Kaposi Sarcoma ADReCS
Ketoacidosis ADReCS
Kidney Diseases MetaADEDB
Kidney Pain MetaADEDB
Kidney Tubular Necrosis Acute MetaADEDB
Laryngitis ADReCS
Laryngospasm ADReCS
Left Ventricular Dysfunction MetaADEDB
Leishmaniasis MetaADEDB
Leishmaniasis Cutaneous MetaADEDB
Leishmaniasis Mucocutaneous MetaADEDB
Leishmaniasis Visceral MetaADEDB
Lethargy ADReCS
Leucopenia MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Lip Erosion MetaADEDB
Lipase MetaADEDB
Lipodystrophy Acquired MetaADEDB
Liver Diseases MetaADEDB
Liver Function Test Abnormal ADReCS
Liver Transplant Rejection MetaADEDB
Long Qt Syndrome MetaADEDB
Loss Of Weight MetaADEDB
Lung Diseases Interstitial MetaADEDB
Lung Disorder ADReCS
Malnourished MetaADEDB
Melaena ADReCS
Meningitis Cryptococcal ADReCS
Mental Status Changes MetaADEDB
Metabolic Encephalopathy MetaADEDB
Middle Ear Inflammation MetaADEDB
Mouth Diseases MetaADEDB
Mouth Ulceration ADReCS
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort MetaADEDB
Myalgia ADReCS
Mycobacterium Avium Complex Infection MetaADEDB
Mycoplasma Infection ADReCS
Myocardial Stunning MetaADEDB
Myoglobinuria MetaADEDB
Myringotomy MetaADEDB
Nasal Congestion ADReCS
Nausea ADReCS
Necrosis ADReCS
Neoplasia MetaADEDB
Nephritis ADReCS
Nephrotic Syndrome MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neuralgia ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
Night Sweats ADReCS
Nodule Skin MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Ocular Icterus MetaADEDB
Oedema Peripheral ADReCS
Oesophageal Candidiasis ADReCS
Oesophageal Varices Haemorrhage MetaADEDB
Oesophagitis ADReCS
Opportunistic Infection MetaADEDB
Oral Candidiasis ADReCS
Oral Herpes ADReCS
Pain ADReCS
Palpitations ADReCS
Pancreatic Diseases MetaADEDB
Pancreatitis ADReCS
Pancytopenia ADReCS
Paraesthesia ADReCS
Paranoia ADReCS
Parosmia ADReCS
Peripheral Sensory Neuropathy ADReCS
Pharyngitis ADReCS
Phlebitis ADReCS
Platelet Count MetaADEDB
Pleurisy ADReCS
Pneumocystis Infections MetaADEDB
Pneumocystis Jiroveci Infection ADReCS
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Bacterial ADReCS
Pneumonia Pneumocystis MetaADEDB
Pneumothorax ADReCS
Portal Hypertension MetaADEDB
Proteinuria MetaADEDB
Pruritus ADReCS
Pyrexia ADReCS
Quadriparesis MetaADEDB
Rales ADReCS
Rash ADReCS
Renal Disorder ADReCS
Renal Failure ADReCS
Renal Impairment ADReCS
Renal Insufficiency MetaADEDB
Renal Pain ADReCS
Respiratory Failure MetaADEDB
Respiratory Tract Congestion ADReCS
Retching ADReCS
Reversible Posterior Leukoencephalopathy Syndrome MetaADEDB
Rhinitis ADReCS
Salivary Hypersecretion ADReCS
Sciatic Neuropathy MetaADEDB
Sinus Operation MetaADEDB
Sinusitis ADReCS
Skin Exfoliation ADReCS
Skin Lesion MetaADEDB
Skin Odour Abnormal ADReCS
Somnolence ADReCS
Splenomegaly ADReCS
Sputum Abnormal ADReCS
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stress MetaADEDB
Syncope ADReCS
Synostosis MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tachypnoea ADReCS
Taste Disorders MetaADEDB
Temperature Regulation Disorder ADReCS
Therapeutic Response Decreased MetaADEDB
Thrombocytopenia ADReCS
Tonsillitis ADReCS
Tooth Disease MetaADEDB
Tooth Impacted MetaADEDB
Tooth Loss MetaADEDB
Torsade De Pointes ADReCS
Torsades De Pointes MetaADEDB
Transaminases Increased MetaADEDB
Treatment Noncompliance MetaADEDB
Tremor ADReCS
Trichorrhexis ADReCS
Trypanosomiasis MetaADEDB
Trypanosomiasis African MetaADEDB
Tuberculosis ADReCS
Tubulointerstitial Nephritis MetaADEDB
Upper Respiratory Disorder ADReCS
Urticaria ADReCS
Urticaria Generalised MetaADEDB
Vasculitis ADReCS
Vasodilatation ADReCS
Venoocclusive Liver Disease MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Vestibular Diseases MetaADEDB
Vision Blurred ADReCS
Vomiting ADReCS
Wheezing ADReCS
Wound Debridement MetaADEDB

InAADR: Drug-Protein-ADRs database