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Drugs Causing Toxic Epidermal Necrolysis: 254
Drug Name
CAS Number
Source
Abacavir
136470-78-5
ADReCS
Acetazolamide
59-66-5
ADReCS
Acetyl Sulfisoxazole
80-74-0
ADReCS
Aciclovir
59277-89-3
ADReCS
Aclidinium
727649-81-2
ADReCS
Alendronate
66376-36-1
ADReCS
Alendronate Sodium
121268-17-5
MetaADEDB
Aliskiren
173334-57-1
PROTECT
Allopurinol
315-30-0
ADReCS
Amifostine
20537-88-6
ADReCS
Amiodarone
1951-25-3
ADReCS
Amlodipine
88150-42-9
ADReCS
Amoxicillin
26787-78-0
ADReCS
Amphetamine
300-62-9
ADReCS
Amphotericin B
1397-89-3
ADReCS
Aprepitant
170729-80-3
ADReCS
Atenolol
29122-68-7
ADReCS
Atorvastatin
134523-00-5
ADReCS
Azathioprine
446-86-6
MetaADEDB
Azithromycin
83905-01-5
ADReCS
Aztreonam
78110-38-0
ADReCS
Bendamustine
16506-27-7
ADReCS
Betaxolol
63659-18-7
ADReCS
Bezafibrate
41859-67-0
ADReCS
Bisoprolol
66722-44-9
ADReCS
Bleomycin
11056-06-7
ADReCS
Bortezomib
179324-69-7
ADReCS
Bumetanide
28395-03-1
ADReCS
Carbamazepine
298-46-4
ADReCS
Carvedilol
72956-09-3
ADReCS
Cefaclor
53994-73-3
ADReCS
Cefadroxil
66592-87-8
ADReCS
Cefazolin
25953-19-9
ADReCS
Cefdinir
91832-40-5
ADReCS
Cefditoren
104145-95-1
ADReCS
Cefepime
88040-23-7
ADReCS
Cefixime
79350-37-1
ADReCS
Cefotaxime
63527-52-6
ADReCS
Cefotetan
69712-56-7
ADReCS
Cefoxitin
35607-66-0
ADReCS
cefpodoxime
82619-04-3
SIDER
Cefprozil
92665-29-7
ADReCS
Ceftazidime
78439-06-2
SIDER
Ceftibuten
97519-39-6
ADReCS
Ceftizoxime
68401-81-0
ADReCS
Ceftriaxone
73384-59-5
ADReCS
Cefuroxime
55268-75-2
ADReCS
Celecoxib
169590-42-5
ADReCS
Cephalexin
15686-71-2
ADReCS
cephem
CASNA513
SIDER
Cerivastatin
145599-86-6
ADReCS
Certolizumab pegol
428863-50-7
ADReCS
Cetirizine
83881-51-0
ADReCS
Cetuximab
205923-56-4
PROTECT
Chlorambucil
305-03-3
ADReCS
Chloroquine
54-05-7
ADReCS
Chlorothiazide
58-94-6
ADReCS
Chlorthalidone
77-36-1
ADReCS
Cilazapril
92077-78-6
SIDER
Cimetidine
51481-61-9
ADReCS
Cinoxacin
28657-80-9
ADReCS
Ciprofloxacin
85721-33-1
ADReCS
Citalopram
59729-33-8
ADReCS
Cladribine
4291-63-8
ADReCS
Clarithromycin
81103-11-9
ADReCS
Clindamycin
18323-44-9
ADReCS
Clobazam
22316-47-8
ADReCS
Clofarabine
123318-82-1
ADReCS
Clopidogrel
113665-84-2
ADReCS
Clozapine
5786-21-0
ADReCS
Conivaptan
210101-16-9
ADReCS
Cyclophosphamide
50-18-0
ADReCS
Cytosine
71-30-7
ADReCS
Dapsone
80-08-0
ADReCS
Darunavir
206361-99-1
ADReCS
Delavirdine
136817-59-9
ADReCS
Desvenlafaxine
93413-62-8
ADReCS
Diclofenac
15307-86-5
ADReCS
Diflunisal
22494-42-4
ADReCS
Diltiazem
42399-41-7
ADReCS
Divalproex Sodium
76584-70-8
ADReCS
Docetaxel
114977-28-5
ADReCS
Doripenem
148016-81-3
ADReCS
Doxorubicin
23214-92-8
ADReCS
Doxycycline
564-25-0
ADReCS
Efavirenz
154598-52-4
ADReCS
Enalapril
75847-73-3
ADReCS
enalapril maleate
76095-16-4
SIDER
Enalaprilat
76420-72-9
ADReCS
Entacapone
130929-57-6
ADReCS
Erlotinib
183321-74-6
PROTECT
Erythromycin
114-07-8
ADReCS
Escitalopram
128196-01-0
ADReCS
Esomeprazole
119141-88-7
ADReCS
Etanercept
185243-69-0
ADReCS
Etodolac
41340-25-4
ADReCS
Etoposide
33419-42-0
ADReCS
Etravirine
269055-15-4
ADReCS
exenatide
141758-74-9
SIDER
Famciclovir
104227-87-4
ADReCS
Famotidine
76824-35-6
ADReCS
Febuxostat
144060-53-7
ADReCS
Felbamate
25451-15-4
ADReCS
Fenoprofen
34597-40-5
SIDER
Fentanyl
437-38-7
ADReCS
Fluconazole
86386-73-4
ADReCS
Flucytosine
2022-85-7
ADReCS
Fludarabine
21679-14-1
SIDER
Fluoride Ion
16984-48-8
ADReCS
Fluoxetine
54910-89-3
ADReCS
Flurbiprofen
5104-49-4
ADReCS
Flutamide
13311-84-7
ADReCS
Fluvastatin
93957-54-1
ADReCS
Fluvoxamine
54739-18-3
ADReCS
Formoterol
73573-87-2
ADReCS
Fosaprepitant
172673-20-0
PROTECT
Foscarnet
63585-09-1
SIDER
Furosemide
54-31-9
ADReCS
Gadopentetate dimeglumine
86050-77-3
ADReCS
Galactose
10257-28-0
ADReCS
Gefitinib
184475-35-2
ADReCS
Glycopeptide Antibiotic
CASNA527
ADReCS
Hydrochlorothiazide
58-93-5
ADReCS
Ibritumomab
174722-31-7
ADReCS
Ibuprofen
15687-27-1
ADReCS
Imatinib
152459-95-5
ADReCS
Indapamide
26807-65-8
ADReCS
Indomethacin
53-86-1
ADReCS
Infliximab
170277-31-3
ADReCS
Interferon Alfa-2a Recombinant
76543-88-9
ADReCS
Interferon alfacon-1
118390-30-0
ADReCS
Ipilimumab
477202-00-9
PROTECT
Isosulfan Blue
68238-36-8
ADReCS
Isotretinoin
4759-48-2
ADReCS
Itraconazole
84625-61-6
ADReCS
Ivermectin
70288-86-7
ADReCS
Ketoprofen
22071-15-4
ADReCS
Ketorolac
66635-83-4
ADReCS
Lamotrigine
84057-84-1
ADReCS
Lansoprazole
103577-45-3
ADReCS
Latanoprost
130209-82-4
ADReCS
Leflunomide
75706-12-6
ADReCS
Lenalidomide
191732-72-6
ADReCS
Letrozole
112809-51-5
ADReCS
Leuprolide
53714-56-0
ADReCS
Leuprolide acetate
74381-53-6
SIDER
Levetiracetam
102767-28-2
PROTECT
Levofloxacin
100986-85-4
ADReCS
Levonorgestrel
797-63-7
ADReCS
Lisdexamfetamine
608137-32-2
ADReCS
Lisinopril
83915-83-7
ADReCS
Lomefloxacin
98079-51-7
ADReCS
Loperamide
53179-11-6
ADReCS
Loracarbef
76470-66-1
ADReCS
Losartan
114798-26-4
ADReCS
Lovastatin
75330-75-5
ADReCS
Medroxyprogesterone
520-85-4
ADReCS
Medrysone
2668-66-8
ADReCS
Meloxicam
71125-38-7
ADReCS
Mephenytoin
50-12-4
ADReCS
Meropenem
119478-56-7
ADReCS
Mesna
19767-45-4
ADReCS
Methazolamide
554-57-4
ADReCS
Methotrexate
59-05-2
ADReCS
Methyldopa
555-30-6
ADReCS
Methyldopate
6014-30-8
ADReCS
Methylphenidate
113-45-1
ADReCS
Metolazone
17560-51-9
ADReCS
Metronidazole
443-48-1
ADReCS
Micafungin
235114-32-6
PROTECT
Minocycline
10118-90-8
ADReCS
Mirtazapine
61337-67-5
ADReCS
Modafinil
68693-11-8
ADReCS
Mometasone
105102-22-5
ADReCS
Moxifloxacin
151096-09-2
ADReCS
Nabumetone
42924-53-8
ADReCS
Naproxen
22204-53-1
ADReCS
Nevirapine
129618-40-2
ADReCS
Nifedipine
21829-25-4
ADReCS
Norfloxacin
70458-96-7
ADReCS
Ofloxacin
82419-36-1
ADReCS
Olmesartan
144689-24-7
ADReCS
olmesartan medoxomil
144689-63-4
SIDER
Omeprazole
73590-58-6
ADReCS
Ondansetron
99614-02-5
ADReCS
oseltamivir
204255-11-8
MetaADEDB
Oxaprozin
21256-18-8
ADReCS
Oxcarbazepine
28721-07-5
ADReCS
Paclitaxel
33069-62-4
ADReCS
Pantoprazole
102625-70-7
ADReCS
Parecoxib
202409-33-4
PROTECT
Paroxetine
61869-08-7
ADReCS
Peginterferon alfa-2a
198153-51-4
PROTECT
Pemetrexed
137281-23-3
SIDER
Penicillamine
52-67-5
ADReCS
Pentazocine
359-83-1
ADReCS
Phenobarbital
50-06-6
ADReCS
Phenytoin
57-41-0
ADReCS
Piperacillin
66258-76-2
SIDER
Polythiazide
346-18-9
ADReCS
Pralatrexate
146464-95-1
ADReCS
Pravastatin
81093-37-0
ADReCS
Procarbazine
671-16-9
ADReCS
Propranolol
525-66-6
ADReCS
Pyrimethamine
58-14-0
ADReCS
Quinidine
56-54-2
ADReCS
Quinine
130-95-0
ADReCS
Rabeprazole
117976-89-3
ADReCS
Ramipril
87333-19-5
ADReCS
Ribavirin
36791-04-5
ADReCS
Rifampicin
13292-46-1
ADReCS
Ritonavir
155213-67-5
ADReCS
Rivastigmine
123441-03-2
ADReCS
Rizatriptan
145202-66-0
ADReCS
Rofecoxib
162011-90-7
ADReCS
Saccharated Iron Oxide
8047-67-4
ADReCS
Salsalate
552-94-3
ADReCS
Sertraline
79617-96-2
ADReCS
Sildenafil
139755-83-2
PROTECT
Simvastatin
79902-63-9
ADReCS
Sorafenib
284461-73-0
ADReCS
Spironolactone
52-01-7
ADReCS
strontium ranelate
135459-87-9
PROTECT
Sulfacetamide
144-80-9
ADReCS
Sulfadiazine
68-35-9
ADReCS
Sulfasalazine
599-79-1
ADReCS
Sulfisoxazole
127-69-5
ADReCS
Sulindac
38194-50-2
ADReCS
sunitinib
557795-19-4
PROTECT
Tacrolimus
104987-11-3
ADReCS
Tazarotene
118292-40-3
ADReCS
Telaprevir
402957-28-2
PROTECT
Temozolomide
85622-93-1
ADReCS
Terbinafine
91161-71-6
ADReCS
Testosterone
58-22-0
ADReCS
Thalidomide
50-35-1
ADReCS
Tipranavir
174484-41-4
ADReCS
Tolazamide
1156-19-0
ADReCS
Tolmetin
26171-23-3
ADReCS
Topiramate
97240-79-4
ADReCS
Torasemide
56211-40-6
ADReCS
Tramadol
27203-92-5
ADReCS
Tretinoin
302-79-4
ADReCS
Trimethoprim
738-70-5
ADReCS
Valdecoxib
181695-72-7
ADReCS
Valproic Acid
99-66-1
ADReCS
Vancomycin
1404-90-6
ADReCS
Vemurafenib
918504-65-1
ADReCS
Venlafaxine
93413-69-5
ADReCS
Vigabatrin
60643-86-9
ADReCS
Voriconazole
137234-62-9
ADReCS
Zanamivir
139110-80-8
ADReCS
Zidovudine
30516-87-1
ADReCS
Zonisamide
68291-97-4
PROTECT
List of proteins causing Toxic Epidermal Necrolysis
Protein Name
Uniprot ID
Source
Cytochrome P450 2C9
P11712
22722194
Prostaglandin G/H synthase 1 precursor
P23219
22722194
Serum albumin precursor
P02768
22722194
InAADR: Drug-Protein-ADRs database