Drugs Causing Skin Necrosis: 143
Drug Name	CAS Number	Source
Acebutolol	37517-30-9	MetaADEDB
Alglucosidase alfa	420784-05-0	ADReCS
Allopurinol	315-30-0	MetaADEDB
Amiodarone	1951-25-3	ADReCS
Ampicillin	69-53-4	MetaADEDB
Anastrozole	120511-73-1	MetaADEDB
Arginine	74-79-3	ADReCS
Benazepril	86541-75-5	MetaADEDB
Bendamustine	16506-27-7	ADReCS
Bepotastine	125602-71-3	MetaADEDB
betamethasone dipropionate	5593-20-4	MetaADEDB
Bisacodyl	603-50-9	MetaADEDB
Bosentan	147536-97-8	MetaADEDB
Brotizolam	57801-81-7	MetaADEDB
buflomedil	55837-25-7	MetaADEDB
Bumetanide	28395-03-1	MetaADEDB
Buprenorphine	52485-79-7	MetaADEDB
Calcitriol	32222-06-3	MetaADEDB
Carmustine	154-93-8	ADReCS
Cefepime	88040-23-7	MetaADEDB
Cefixime	79350-37-1	MetaADEDB
Cefotaxime	63527-52-6	MetaADEDB
Cefotiam	61622-34-2	MetaADEDB
Cefprozil	92665-29-7	MetaADEDB
Cephalexin	15686-71-2	MetaADEDB
Cetuximab	205923-56-4	PROTECT
Chlorambucil	305-03-3	MetaADEDB
Chlorhexidine	55-56-1	MetaADEDB
Chlorhexidine gluconate	18472-51-0	MetaADEDB
Chloroquine	54-05-7	MetaADEDB
Chlorpromazine	50-53-3	MetaADEDB
Cinacalcet	226256-56-0	MetaADEDB
Clindamycin	18323-44-9	MetaADEDB
coenzyme Q10	303-98-0	MetaADEDB
Cyclobenzaprine	303-53-7	MetaADEDB
Desirudin	120993-53-5	ADReCS
Diatrizoate	117-96-4	ADReCS
Dicloxacillin	3116-76-5	MetaADEDB
dihydrocodeine	125-28-0	MetaADEDB
dimethindene	5636-83-9	MetaADEDB
Dobutamine	34368-04-2	ADReCS
docusate	577-11-7	MetaADEDB
Doxazosin	74191-85-8	MetaADEDB
Doxorubicin	23214-92-8	ADReCS
Dutasteride	164656-23-9	MetaADEDB
Efavirenz	154598-52-4	MetaADEDB
Enoxaparin	9005-49-6	ADReCS
Epinephrine	51-43-4	MetaADEDB
Erythromycin	114-07-8	MetaADEDB
Escitalopram	128196-01-0	ADReCS
Esmolol	100286-90-6	ADReCS
Estradiol	50-28-2	MetaADEDB
Etomidate	33125-97-2	MetaADEDB
Etoposide	33419-42-0	ADReCS
Famotidine	76824-35-6	MetaADEDB
Ferrous fumarate	141-01-5	MetaADEDB
Fluindione	957-56-2	MetaADEDB
Fulvestrant	129453-61-8	MetaADEDB
Gabapentin	60142-96-3	ADReCS
gadobenate	127000-20-8	MetaADEDB
Gadoteridol	120066-54-8	MetaADEDB
Gadoversetamide	131069-91-5	MetaADEDB
Galactose	10257-28-0	MetaADEDB
Gemfibrozil	25812-30-0	MetaADEDB
Gentamicin	1403-66-3	MetaADEDB
Glatiramer Acetate	147245-92-9	ADReCS
glycerol	56-81-5	MetaADEDB
Goserelin	65807-02-5	ADReCS
hydrocodone	125-29-1	MetaADEDB
Hydromorphone	466-99-9	MetaADEDB
Hydroxyurea	127-07-1	ADReCS
Ifosfamide	3778-73-2	ADReCS
imipenem	74431-23-5	MetaADEDB
Imipramine	50-49-7	MetaADEDB
Indapamide	26807-65-8	MetaADEDB
Iopamidol	60166-93-0	ADReCS
Isoniazid	54-85-3	MetaADEDB
Isradipine	75695-93-1	MetaADEDB
Latanoprost	130209-82-4	MetaADEDB
Leflunomide	75706-12-6	MetaADEDB
Letrozole	112809-51-5	MetaADEDB
Mafenide	138-39-6	ADReCS
magnesium hydroxide	1309-42-8	MetaADEDB
Mannitol	69-65-8	ADReCS
melatonin	73-31-4	MetaADEDB
Melphalan	148-82-3	ADReCS
Meprobamate	57-53-4	MetaADEDB
Mesalazine	89-57-6	ADReCS
Methotrexate	59-05-2	ADReCS
methylprednisolone acetate	53-36-1	MetaADEDB
Metolazone	17560-51-9	ADReCS
Micafungin	235114-32-6	ADReCS
Midazolam	59467-70-8	ADReCS
Minocycline	10118-90-8	MetaADEDB
Mitoxantrone	65271-80-9	MetaADEDB
Mometasone	105102-22-5	MetaADEDB
Naproxen	22204-53-1	ADReCS
Naratriptan	121679-13-8	MetaADEDB
Nicorandil	65141-46-0	MetaADEDB
Nilvadipine	75530-68-6	MetaADEDB
Nisoldipine	63675-72-9	MetaADEDB
Nitroglycerin	55-63-0	MetaADEDB
Nortriptyline	72-69-5	MetaADEDB
Orphenadrine	83-98-7	MetaADEDB
Pamidronate	40391-99-9	MetaADEDB
Panitumumab	339177-26-3	ADReCS
Parecoxib	202409-33-4	MetaADEDB
Paricalcitol	131918-61-1	MetaADEDB
Paroxetine	61869-08-7	MetaADEDB
Penicillin G benzathine	1538-09-6	MetaADEDB
Pethidine	57-42-1	MetaADEDB
Phenprocoumon	435-97-2	MetaADEDB
Piroxicam	36322-90-4	MetaADEDB
Polythiazide	346-18-9	ADReCS
Posaconazole	171228-49-2	MetaADEDB
Prazepam	2955-38-6	MetaADEDB
Pregabalin	148553-50-8	ADReCS
Quinidine	56-54-2	MetaADEDB
Repaglinide	135062-02-1	MetaADEDB
rilmenidine	54187-04-1	MetaADEDB
selenium	7782-49-2	MetaADEDB
Sevelamer	152751-57-0	MetaADEDB
Silver sulfadiazine	22199-08-2	ADReCS
Sitaxentan	210421-64-0	MetaADEDB
Sodium bicarbonate	144-55-8	MetaADEDB
Tacrine	321-64-2	ADReCS
Tamoxifen	10540-29-1	MetaADEDB
Tazobactam	89786-04-9	MetaADEDB
Tegafur	17902-23-7	MetaADEDB
Telithromycin	191114-48-4	MetaADEDB
Temoporfin	122341-38-2	PROTECT
Terazosin	63590-64-7	MetaADEDB
Terbutaline	23031-25-6	MetaADEDB
Thalidomide	50-35-1	ADReCS
Thiotepa	52-24-4	MetaADEDB
Tretinoin	302-79-4	MetaADEDB
Valdecoxib	181695-72-7	MetaADEDB
Valrubicin	56124-62-0	ADReCS
Vancomycin	1404-90-6	MetaADEDB
Verteporfin	129497-78-5	MetaADEDB
Vinorelbine	71486-22-1	ADReCS
Warfarin	81-81-2	ADReCS
Zafirlukast	107753-78-6	MetaADEDB

List of proteins causing Skin Necrosis
Protein Name	Uniprot ID	Source