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Drugs Causing Respiratory Depression: 85
Drug Name
CAS Number
Source
Acetaminophen
103-90-2
ADReCS
Alfentanil
71195-58-9
ADReCS
Alprostadil
745-65-3
ADReCS
Aprepitant
170729-80-3
ADReCS
Atropine
51-55-8
ADReCS
Baclofen
1134-47-0
ADReCS
Bosentan
147536-97-8
ADReCS
Botulinum Toxin Type A
93384-43-1
ADReCS
Brimonidine
59803-98-4
ADReCS
Bromazepam
1812-30-2
ADReCS
Bupivacaine
2180-92-9
ADReCS
Buprenorphine
52485-79-7
ADReCS
Butorphanol
42408-82-2
ADReCS
Carbamazepine
298-46-4
ADReCS
Clobazam
22316-47-8
ADReCS
Clonazepam
1622-61-3
ADReCS
Codeine
76-57-3
ADReCS
Conjugated Estrogens
438-67-5
ADReCS
Dantrolene
7261-97-4
ADReCS
Dexmedetomidine
113775-47-6
ADReCS
Diazepam
439-14-5
ADReCS
Diclofenac
15307-86-5
ADReCS
Enflurane
13838-16-9
ADReCS
Etodolac
41340-25-4
ADReCS
Febuxostat
144060-53-7
ADReCS
Felbamate
25451-15-4
ADReCS
Fenoprofen
34597-40-5
ADReCS
Fentanyl
437-38-7
ADReCS
Flurbiprofen
5104-49-4
ADReCS
gadofosveset
211570-55-7
SIDER
Gadofosveset trisodium
193901-90-5
ADReCS
Gentamicin
1403-66-3
ADReCS
Hydromorphone
466-99-9
ADReCS
Hydroxyzine
68-88-2
ADReCS
Ibuprofen
15687-27-1
ADReCS
Insulin Glulisine
207748-29-6
ADReCS
Iodine
7553-56-2
ADReCS
Iodixanol
92339-11-2
ADReCS
Isoflurane
26675-46-7
ADReCS
Ketamine
6740-88-1
ADReCS
Ketorolac
66635-83-4
ADReCS
Levetiracetam
102767-28-2
ADReCS
Lidocaine
137-58-6
ADReCS
Lomefloxacin
98079-51-7
ADReCS
Lorazepam
846-49-1
ADReCS
Mafenide
138-39-6
ADReCS
Magnesium
7439-95-4
ADReCS
Mannitol
69-65-8
ADReCS
Mefenamic acid
61-68-7
ADReCS
Meloxicam
71125-38-7
ADReCS
Methadone
76-99-3
ADReCS
Methohexital
151-83-7
ADReCS
Midazolam
59467-70-8
ADReCS
Morphine
57-27-2
ADReCS
Naproxen
22204-53-1
ADReCS
Neostigmine
59-99-4
ADReCS
Ofloxacin
82419-36-1
ADReCS
Oxaprozin
21256-18-8
ADReCS
Oxycodone
76-42-6
ADReCS
Oxymorphone
76-41-5
ADReCS
Pentazocine
359-83-1
ADReCS
Pethidine
57-42-1
ADReCS
Phenelzine
51-71-8
ADReCS
Phenobarbital
50-06-6
ADReCS
Physostigmine
57-47-6
ADReCS
Piroxicam
36322-90-4
ADReCS
Pregabalin
148553-50-8
ADReCS
Prilocaine
721-50-6
ADReCS
Promethazine
60-87-7
ADReCS
Propofol
2078-54-8
ADReCS
Propoxyphene
469-62-5
ADReCS
Remifentanil
132875-61-7
ADReCS
Riluzole
1744-22-5
ADReCS
Selegiline
14611-51-9
ADReCS
Sodium Oxybate
502-85-2
PROTECT
Succinylcholine
306-40-1
ADReCS
Sufentanil
56030-54-7
ADReCS
Tacrolimus
104987-11-3
ADReCS
Tamoxifen
10540-29-1
ADReCS
Tapentadol
175591-23-8
SIDER
Tobramycin
32986-56-4
ADReCS
Tramadol
27203-92-5
ADReCS
Tris-Hcl
1185-53-1
ADReCS
Tromethamine
77-86-1
ADReCS
Vecuronium
50700-72-6
ADReCS
List of proteins causing Respiratory Depression
Protein Name
Uniprot ID
Source
delta-Type opioid receptor
P41143
22722194
Gamma-aminobutyric acid receptor subunit alpha-1 precursor
P14867
22722194
Gamma-aminobutyric acid receptor subunit alpha-2 precursor
P47869
22722194
Gamma-aminobutyric acid receptor subunit alpha-3 precursor
P34903
22722194
Gamma-aminobutyric acid receptor subunit alpha-4 precursor
P48169
22722194
Gamma-aminobutyric acid receptor subunit alpha-5 precursor
P31644
22722194
Gamma-aminobutyric acid receptor subunit alpha-6 precursor
P30191
22722194
Gamma-aminobutyric acid receptor subunit beta-1 precursor
P15431
22722194
Gamma-aminobutyric acid receptor subunit beta-2 precursor
P63138
22722194
Gamma-aminobutyric acid receptor subunit beta-3 precursor
P28472
22722194
gamma-aminobutyric acid receptor subunit delta precursor
O14764
22722194
gamma-aminobutyric acid receptor subunit epsilon precursor
P78334
22722194
Gamma-aminobutyric acid receptor subunit gamma-1 precursor
Q8N1C3
22722194
Gamma-aminobutyric acid receptor subunit gamma-2 precursor
P18507
22722194
Gamma-aminobutyric acid receptor subunit gamma-3 precursor
Q99928
22722194
gamma-aminobutyric acid receptor subunit pi precursor
O00591
22722194
gamma-aminobutyric acid receptor subunit theta precursor
Q9UN88
22722194
Glutamate receptor 2 precursor
P19491
22722194
Glycine receptor subunit alpha-1 precursor
P23415
22722194
Kappa-Type opioid receptor
P41145
22722194
Mu-Type opioid receptor
P35372
22722194
Neuronal acetylcholine receptor subunit alpha-4 precursor
P43681
22722194
Neuronal acetylcholine receptor subunit alpha-7 precursor
P36544
22722194
protein Grin3a
A2AIR4
22722194
Serine/threonine-protein kinase GRIK2
Q5HZ38
22722194
Sigma non-opioid intracellular receptor 1
Q99720
22722194
utamate receptor ionotropic, NMDA 1 precursor
P35438
22722194
utamate receptor ionotropic,NMDA 2A precursor
Q12879
22722194
InAADR: Drug-Protein-ADRs database