Drugs Causing Renal Impairment: 421
Drug Name	CAS Number	Source
Abacavir	136470-78-5	MetaADEDB
Abciximab	143653-53-6	ADReCS
AC-17	51460-26-5	MetaADEDB
Acarbose	56180-94-0	MetaADEDB
Aciclovir	59277-89-3	ADReCS
Acitretin	55079-83-9	MetaADEDB
Adalimumab	331731-18-1	PROTECT
Adefovir	106941-25-7	PROTECT
Adefovir Dipivoxil	142340-99-6	ADReCS
Aldioxa	5579-81-7	MetaADEDB
Alfacalcidol	41294-56-8	MetaADEDB
Alfentanil	71195-58-9	MetaADEDB
Alfuzosin	81403-80-7	ADReCS
Aliskiren	173334-57-1	PROTECT
Allopurinol	315-30-0	ADReCS
Amantadine	768-94-5	MetaADEDB
Amikacin	37517-28-5	ADReCS
Amiodarone	1951-25-3	ADReCS
Amisulpride	53583-79-2	MetaADEDB
Amoxapine	14028-44-5	MetaADEDB
Amoxicillin	26787-78-0	ADReCS
Amphotericin B	1397-89-3	ADReCS
Ampicillin	69-53-4	MetaADEDB
Anagrelide	68475-42-3	ADReCS
Aprotinin	9087-70-1	ADReCS
Arbekacin	51025-85-5	MetaADEDB
Argatroban	74863-84-6	ADReCS
Arotinolol	41287-43-8	MetaADEDB
Arsenic trioxide	1327-53-3	ADReCS
Atazanavir	198904-31-3	MetaADEDB
Atenolol	29122-68-7	ADReCS
Atovaquone	95233-18-4	ADReCS
Auranofin	34031-32-8	MetaADEDB
Azasetron	123040-69-7	MetaADEDB
Azathioprine	446-86-6	MetaADEDB
Azelnidipine	123524-52-7	MetaADEDB
Azithromycin	83905-01-5	MetaADEDB
Azosemide	27589-33-9	MetaADEDB
Basiliximab	179045-86-4	ADReCS
Belatacept	706808-37-9	ADReCS
Bendroflumethiazide	73-48-3	MetaADEDB
benfluorex	23602-78-0	MetaADEDB
benidipine	105979-17-7	MetaADEDB
benzbromarone	3562-84-3	MetaADEDB
Bepotastine	125602-71-3	MetaADEDB
Bepridil	64706-54-3	MetaADEDB
beraprost sodium	88475-69-8	MetaADEDB
beta-Methyldigoxin	30685-43-9	MetaADEDB
Betahistine	5638-76-6	MetaADEDB
Betaxolol	63659-18-7	ADReCS
Bexarotene	153559-49-0	ADReCS
Bezafibrate	41859-67-0	MetaADEDB
Biapenem	120410-24-4	MetaADEDB
Bisolvon	3572-43-8	MetaADEDB
Bortezomib	179324-69-7	PROTECT
Bosentan	147536-97-8	ADReCS
bosutinib	380843-75-4	PROTECT
Brotizolam	57801-81-7	MetaADEDB
Bucillamine	65002-17-7	MetaADEDB
Bumetanide	28395-03-1	MetaADEDB
Calcitriol	32222-06-3	ADReCS
Candesartan	139481-59-7	ADReCS
Candesartan cilexetil	145040-37-5	MetaADEDB
Capecitabine	154361-50-9	ADReCS
Carbidopa	28860-95-9	MetaADEDB
Carboplatin	41575-94-4	ADReCS
Carvedilol	72956-09-3	ADReCS
Caspofungin	179463-17-3	ADReCS
Cefaclor	53994-73-3	ADReCS
Cefadroxil	66592-87-8	ADReCS
Cefazolin	25953-19-9	ADReCS
Cefdinir	91832-40-5	ADReCS
Cefditoren	104145-95-1	ADReCS
Cefepime	88040-23-7	ADReCS
Cefixime	79350-37-1	ADReCS
Cefotaxime	63527-52-6	ADReCS
Cefotetan	69712-56-7	ADReCS
Cefotiam	61622-34-2	MetaADEDB
Cefoxitin	35607-66-0	ADReCS
cefpirome	84957-29-9	MetaADEDB
cefpodoxime	82619-04-3	SIDER
Cefprozil	92665-29-7	ADReCS
Ceftazidime	78439-06-2	SIDER
Ceftibuten	97519-39-6	ADReCS
Ceftizoxime	68401-81-0	ADReCS
Ceftriaxone	73384-59-5	ADReCS
Cefuroxime	55268-75-2	ADReCS
Celecoxib	169590-42-5	MetaADEDB
Cephalexin	15686-71-2	ADReCS
Cerivastatin	145599-86-6	ADReCS
Cevimeline	107233-08-9	ADReCS
Chloramphenicol	56-75-7	MetaADEDB
Chlorhexidine gluconate	18472-51-0	MetaADEDB
Chlorphenamine	132-22-9	MetaADEDB
Chlorzoxazone	95-25-0	MetaADEDB
Cibenzoline	53267-01-9	MetaADEDB
Cilazapril	92077-78-6	SIDER
Cilnidipine	132203-70-4	MetaADEDB
Cilostazol	73963-72-1	MetaADEDB
Ciprofloxacin	85721-33-1	ADReCS
Cisplatin	15663-27-1	ADReCS
Clarithromycin	81103-11-9	MetaADEDB
Clindamycin	18323-44-9	MetaADEDB
clindamycin phosphate	24729-96-2	MetaADEDB
Clodronate	10596-23-3	ADReCS
Clofarabine	123318-82-1	MetaADEDB
Clopidogrel	113665-84-2	ADReCS
Clorazepate	23887-31-2	ADReCS
Clozapine	5786-21-0	MetaADEDB
Codeine	76-57-3	MetaADEDB
Colchicine	64-86-8	MetaADEDB
Crotamiton	483-63-6	MetaADEDB
Cyclophosphamide	50-18-0	ADReCS
Cyclosporine	59865-13-3	ADReCS
Cyproterone Acetate	427-51-0	MetaADEDB
Cytosine	71-30-7	ADReCS
Dactinomycin	50-76-0	ADReCS
Danazol	17230-88-5	MetaADEDB
dapagliflozin	461432-26-8	PROTECT
Daptomycin	103060-53-3	ADReCS
Daunorubicin	20830-81-3	MetaADEDB
Deferoxamine	70-51-9	ADReCS
deflazacort	14484-47-0	MetaADEDB
Degarelix	214766-78-6	PROTECT
Deoxythymidine	50-89-5	MetaADEDB
Desirudin	120993-53-5	ADReCS
Dexrazoxane	24584-09-6	MetaADEDB
Dextromethorphan	125-71-3	MetaADEDB
Diclofenac	15307-86-5	ADReCS
Dicloxacillin	3116-76-5	ADReCS
Didanosine	69655-05-6	ADReCS
diflucortolone valerate	59198-70-8	MetaADEDB
Diflunisal	22494-42-4	ADReCS
Digoxin	20830-75-5	MetaADEDB
dihydrocodeine	125-28-0	MetaADEDB
dimemorfan	36309-01-0	MetaADEDB
diphenidol	972-02-1	MetaADEDB
distigmine bromide	15876-67-2	MetaADEDB
Dobutamine	34368-04-2	MetaADEDB
Dofetilide	115256-11-6	MetaADEDB
Dolasetron	115956-12-2	MetaADEDB
Domperidone	57808-66-9	MetaADEDB
Doripenem	148016-81-3	ADReCS
dothiepin	113-53-1	MetaADEDB
Doxazosin	74191-85-8	MetaADEDB
Doxercalciferol	54573-75-0	ADReCS
Doxorubicin	23214-92-8	ADReCS
Duovent	438627-66-8	MetaADEDB
Eculizumab	219685-50-4	PROTECT
Efavirenz	154598-52-4	MetaADEDB
Enalapril	75847-73-3	ADReCS
Enalaprilat	76420-72-9	ADReCS
Enoxaparin	9005-49-6	ADReCS
Entacapone	130929-57-6	MetaADEDB
epalrestat	82159-09-9	MetaADEDB
eperisone	56839-43-1	MetaADEDB
Ephedrine	299-42-3	MetaADEDB
Epinastine	80012-43-7	MetaADEDB
Eplerenone	107724-20-9	ADReCS
Ergocalciferol	50-14-6	ADReCS
Ertapenem	153832-46-3	ADReCS
Erythromycin	114-07-8	ADReCS
Esmolol	100286-90-6	ADReCS
Estazolam	29975-16-4	MetaADEDB
Ethambutol	74-55-5	MetaADEDB
Ethinyl Estradiol	57-63-6	ADReCS
etizolam	40054-69-1	MetaADEDB
Etodolac	41340-25-4	ADReCS
exenatide	141758-74-9	SIDER
Famotidine	76824-35-6	ADReCS
Febuxostat	144060-53-7	ADReCS
Felbamate	25451-15-4	ADReCS
Fenofibrate	49562-28-9	ADReCS
Fioricet	122018-95-5	MetaADEDB
Flavoxate	15301-69-6	MetaADEDB
Flomoxef	99665-00-6	MetaADEDB
Floxacillin	5250-39-5	MetaADEDB
Fluconazole	86386-73-4	MetaADEDB
Fludarabine	21679-14-1	SIDER
Flurbiprofen	5104-49-4	ADReCS
Fluvoxamine	54739-18-3	MetaADEDB
Foscarnet	63585-09-1	SIDER
Fosfluconazole	194798-83-9	MetaADEDB
Frovatriptan	158747-02-5	MetaADEDB
Furosemide	54-31-9	MetaADEDB
Gabapentin	60142-96-3	ADReCS
gabexate mesilate	56974-61-9	MetaADEDB
Gadobenate Dimeglumine	113662-23-0	ADReCS
gadolinium	7440-54-2	MetaADEDB
Gadopentetate dimeglumine	86050-77-3	ADReCS
Ganciclovir	82410-32-0	ADReCS
Gatifloxacin	112811-59-3	ADReCS
Gefitinib	184475-35-2	MetaADEDB
Gemcitabine	95058-81-4	ADReCS
Gemtuzumab ozogamicin	220578-59-6	ADReCS
Gentamicin	1403-66-3	ADReCS
geranylgeranylacetone	6809-52-5	MetaADEDB
Gliclazide	21187-98-4	MetaADEDB
Glimepiride	93479-97-1	MetaADEDB
gliquidone	33342-05-1	MetaADEDB
Glyburide	10238-21-8	MetaADEDB
glycerol	56-81-5	MetaADEDB
Glycopeptide Antibiotic	CASNA527	ADReCS
glycyrrhizin	1405-86-3	MetaADEDB
Granisetron	109889-09-0	MetaADEDB
Guanfacine	29110-47-2	MetaADEDB
Haloperidol	52-86-8	MetaADEDB
Histrelin Acetate	76712-82-8	ADReCS
Hydralazine	86-54-4	MetaADEDB
Hydrochlorothiazide	58-93-5	MetaADEDB
Hydroxyurea	127-07-1	MetaADEDB
Ibuprofen	15687-27-1	ADReCS
Ifosfamide	3778-73-2	ADReCS
Imatinib	152459-95-5	ADReCS
imidapril	89371-37-9	MetaADEDB
imipenem	74431-23-5	MetaADEDB
Imipramine	50-49-7	MetaADEDB
Indapamide	26807-65-8	MetaADEDB
Indinavir	150378-17-9	MetaADEDB
Indomethacin	53-86-1	MetaADEDB
Interferon Alfa-2a Recombinant	76543-88-9	ADReCS
Iodine	7553-56-2	ADReCS
Iodixanol	92339-11-2	ADReCS
Iopamidol	60166-93-0	MetaADEDB
Iopromide	73334-07-3	ADReCS
Ipratropium bromide	22254-24-6	MetaADEDB
Irbesartan	138402-11-6	ADReCS
Isoflurane	26675-46-7	MetaADEDB
Isoniazid	54-85-3	MetaADEDB
Isosorbide Dinitrate	87-33-2	MetaADEDB
Isosorbide Mononitrate	16051-77-7	MetaADEDB
itopride	122898-67-3	MetaADEDB
Itraconazole	84625-61-6	ADReCS
Ketoprofen	22071-15-4	ADReCS
Ketorolac	66635-83-4	ADReCS
L-Carnitine	541-15-1	MetaADEDB
Lafutidine	118288-08-7	MetaADEDB
Lamivudine	134678-17-4	MetaADEDB
Lanreotide	108736-35-2	MetaADEDB
Lansoprazole	103577-45-3	ADReCS
Letrozole	112809-51-5	MetaADEDB
Levetiracetam	102767-28-2	ADReCS
Levofloxacin	100986-85-4	ADReCS
Levothyroxine	51-48-9	MetaADEDB
Liraglutide	204656-20-2	PROTECT
Lisinopril	83915-83-7	MetaADEDB
Lithium	7439-93-2	MetaADEDB
Lornoxicam	70374-39-9	MetaADEDB
Losartan	114798-26-4	ADReCS
Loxoprofen	68767-14-6	MetaADEDB
Lubiprostone	136790-76-6	ADReCS
Madopar	37270-69-2	MetaADEDB
Magnesium	7439-95-4	MetaADEDB
Mannitol	69-65-8	ADReCS
Mefenamic acid	61-68-7	ADReCS
Meloxicam	71125-38-7	ADReCS
Melphalan	148-82-3	MetaADEDB
Memantine	19982-08-2	ADReCS
Mepivacaine	96-88-8	MetaADEDB
Meropenem	119478-56-7	ADReCS
Mesalazine	89-57-6	ADReCS
Mesna	19767-45-4	MetaADEDB
methenolone acetate	434-05-9	MetaADEDB
methylcobalamin	13422-55-4	MetaADEDB
Methyldopa	555-30-6	MetaADEDB
Methylnaltrexone	73232-52-7	ADReCS
Metolazone	17560-51-9	MetaADEDB
Mexiletine	31828-71-4	MetaADEDB
Micafungin	235114-32-6	ADReCS
Miglitol	72432-03-2	MetaADEDB
Milrinone	78415-72-2	MetaADEDB
Mitomycin	50-07-7	ADReCS
Mitotane	53-19-0	MetaADEDB
Mitoxantrone	65271-80-9	MetaADEDB
mizoribine	50924-49-7	MetaADEDB
mosapride	112885-41-3	MetaADEDB
Moxifloxacin	151096-09-2	ADReCS
moxonidine	75438-57-2	MetaADEDB
Mycophenolate mofetil	128794-94-5	ADReCS
Mycophenolic acid	24280-93-1	ADReCS
Nadolol	42200-33-9	MetaADEDB
Nafamostat mesilate	82956-11-4	MetaADEDB
Naftopidil	57149-07-2	MetaADEDB
Naproxen	22204-53-1	ADReCS
Nebivolol	99200-09-6	MetaADEDB
Nelarabine	121032-29-9	MetaADEDB
Nelfinavir	159989-64-7	MetaADEDB
Nevirapine	129618-40-2	PROTECT
Nicardipine	55985-32-5	MetaADEDB
Nicergoline	27848-84-6	MetaADEDB
Nicorandil	65141-46-0	MetaADEDB
Nifedipine	21829-25-4	ADReCS
Nilvadipine	75530-68-6	MetaADEDB
Nitrazepam	146-22-5	MetaADEDB
Nitrofurantoin	67-20-9	ADReCS
Norepinephrine	51-41-2	MetaADEDB
Ofloxacin	82419-36-1	ADReCS
Olanzapine	132539-06-1	MetaADEDB
Oxaprozin	21256-18-8	ADReCS
oxatomide	60607-34-3	MetaADEDB
Oxybutynin	5633-20-5	MetaADEDB
Pamidronate	40391-99-9	MetaADEDB
Pancuronium	15500-66-0	MetaADEDB
Pantethine	16816-67-4	MetaADEDB
Panthenol	16485-10-2	MetaADEDB
Parecoxib	202409-33-4	MetaADEDB
Paroxetine	61869-08-7	ADReCS
Pegvisomant	218620-50-9	PROTECT
Pemetrexed	137281-23-3	MetaADEDB
Penicillamine	52-67-5	MetaADEDB
Penicillin	CASNA522	ADReCS
Penicillin v	87-08-1	MetaADEDB
Pentamidine	100-33-4	ADReCS
Pentazocine	359-83-1	MetaADEDB
Pentostatin	53910-25-1	ADReCS
Perindopril	107133-36-8	ADReCS
Phenelzine	51-71-8	MetaADEDB
Phenytoin	57-41-0	MetaADEDB
Pilsicainide	88069-67-4	MetaADEDB
Pimobendan	74150-27-9	MetaADEDB
Piperacillin	66258-76-2	MetaADEDB
Piracetam	7491-74-9	MetaADEDB
Piretanide	55837-27-9	MetaADEDB
Piroxicam	36322-90-4	ADReCS
Pitavastatin	147511-69-1	MetaADEDB
Polaprezinc	107667-60-7	MetaADEDB
Polyethylene Glycol	25322-68-3	MetaADEDB
Posaconazole	171228-49-2	ADReCS
Pramipexole	104632-26-0	ADReCS
Pranoprofen	52549-17-4	MetaADEDB
Pravastatin	81093-37-0	MetaADEDB
Prazosin	19216-56-9	MetaADEDB
Prednisolone acetate	52-21-1	MetaADEDB
Prednisone	53-03-2	MetaADEDB
Pregabalin	148553-50-8	ADReCS
Promazine	58-40-2	MetaADEDB
Propofol	2078-54-8	MetaADEDB
Pyrazinamide	98-96-4	MetaADEDB
quazepam	36735-22-5	MetaADEDB
Quetiapine	111974-69-7	MetaADEDB
Quinidine	56-54-2	ADReCS
Quinine	130-95-0	ADReCS
Raltegravir	518048-05-0	PROTECT
Raltitrexed	112887-68-0	ADReCS
Ramipril	87333-19-5	ADReCS
rebamipide	90098-04-7	MetaADEDB
Reslin	39471-19-7	MetaADEDB
rilmenidine	54187-04-1	MetaADEDB
Riluzole	1744-22-5	ADReCS
Ritodrine	26652-09-5	MetaADEDB
Ritonavir	155213-67-5	ADReCS
Rivaroxaban	366789-02-8	PROTECT
Rivastigmine	123441-03-2	ADReCS
Rosuvastatin	287714-41-4	MetaADEDB
Saquinavir	127779-20-8	PROTECT
Saxagliptin	361442-04-8	ADReCS
scopolamine	51-34-3	MetaADEDB
simethicone	8050-81-5	MetaADEDB
Sirolimus	53123-88-9	ADReCS
Sitagliptin	486460-32-6	ADReCS
Sitaxentan	210421-64-0	MetaADEDB
Sodium bicarbonate	144-55-8	MetaADEDB
Solifenacin	242478-37-1	ADReCS
Spironolactone	52-01-7	ADReCS
Streptomycin	57-92-1	ADReCS
Sulindac	38194-50-2	ADReCS
sunitinib	557795-19-4	SIDER
Tacrolimus	104987-11-3	ADReCS
Tadalafil	171596-29-5	ADReCS
Tazobactam	89786-04-9	MetaADEDB
Telavancin	372151-71-8	PROTECT
Telmisartan	144701-48-4	ADReCS
Temocapril	111902-57-9	MetaADEDB
Tenofovir	147127-20-6	MetaADEDB
Tenofovir disoproxil fumarate	202138-50-9	MetaADEDB
Terbutryn	886-50-0	MetaADEDB
Teriparatide	52232-67-4	PROTECT
Testosterone	58-22-0	ADReCS
Tetracycline	60-54-8	ADReCS
Thioguanine	154-42-7	MetaADEDB
Thiopental	76-75-5	MetaADEDB
Thiothixene	5591-45-7	MetaADEDB
Tiapride	51012-32-9	MetaADEDB
Ticlopidine	55142-85-3	MetaADEDB
Tigecycline	220620-09-7	ADReCS
Timolol	26839-75-8	MetaADEDB
Tobramycin	32986-56-4	ADReCS
Tolbutamide	64-77-7	MetaADEDB
Tolvaptan	150683-30-0	PROTECT
Torasemide	56211-40-6	MetaADEDB
Tosufloxacin	108138-46-1	MetaADEDB
Tramadol	27203-92-5	ADReCS
Trastuzumab	180288-69-1	PROTECT
Tremorine	51-73-0	MetaADEDB
Triazolam	28911-01-5	MetaADEDB
Trichlormethiazide	133-67-5	MetaADEDB
Trimethoprim	738-70-5	MetaADEDB
Tropisetron	89565-68-4	MetaADEDB
Trovafloxacin	147059-72-1	ADReCS
Troxipide	30751-05-4	MetaADEDB
Tulobuterol	41570-61-0	MetaADEDB
urapidil	34661-75-1	MetaADEDB
Ursodeoxycholic acid	128-13-2	ADReCS
Valaciclovir	124832-26-4	ADReCS
valacyclovir	124832-27-5	MetaADEDB
valganciclovir	175865-60-8	SIDER
Valproic Acid	99-66-1	ADReCS
Valsartan	137862-53-4	ADReCS
Vancomycin	1404-90-6	MetaADEDB
Venlafaxine	93413-69-5	ADReCS
Verteporfin	129497-78-5	MetaADEDB
Vinblastine	865-21-4	MetaADEDB
Vincristine	57-22-7	MetaADEDB
Vinorelbine	71486-22-1	MetaADEDB
voglibose	83480-29-9	MetaADEDB
Voriconazole	137234-62-9	ADReCS
Warfarin	81-81-2	MetaADEDB
Zalcitabine	7481-89-2	ADReCS
Zidovudine	30516-87-1	MetaADEDB
Zoledronate	118072-93-8	PROTECT
Zonisamide	68291-97-4	MetaADEDB

List of proteins causing Renal Impairment
Protein Name	Uniprot ID	Source