Drugs Causing Osteoarthritis: 475
Drug Name	CAS Number	Source
Aceclofenac	89796-99-6	MetaADEDB
Acetaminophen	103-90-2	MetaADEDB
Acetylsalicylic acid	50-78-2	MetaADEDB
Aciclovir	59277-89-3	ADReCS
Acitretin	55079-83-9	ADReCS
Aclidinium	727649-81-2	ADReCS
Albendazole	54965-21-8	MetaADEDB
Alendronate Sodium	121268-17-5	MetaADEDB
Alfuzosin	81403-80-7	ADReCS
Allopurinol	315-30-0	MetaADEDB
Alprazolam	28981-97-7	ADReCS
Amantadine	768-94-5	ADReCS
Amifostine	20537-88-6	MetaADEDB
Amisulpride	53583-79-2	MetaADEDB
Amitriptyline	50-48-6	ADReCS
Amitriptyline Hydrochloride	549-18-8	MetaADEDB
Amlodipine	88150-42-9	ADReCS
Amoxicillin	26787-78-0	MetaADEDB
Ampicillin	69-53-4	MetaADEDB
Anagrelide	68475-42-3	MetaADEDB
Anastrozole	120511-73-1	ADReCS
Aripiprazole	129722-12-9	ADReCS
Articaine Hydrochloride	23964-57-0	MetaADEDB
Asenapine	65576-45-6	ADReCS
Aspartame	22839-47-0	MetaADEDB
Atenolol	29122-68-7	MetaADEDB
Atorvastatin	134523-00-5	MetaADEDB
Atovaquone	95233-18-4	MetaADEDB
Atropine	51-55-8	ADReCS
Azelastine	58581-89-8	MetaADEDB
Azithromycin	83905-01-5	MetaADEDB
Azosemide	27589-33-9	MetaADEDB
Bacitracin	1405-87-4	MetaADEDB
Baclofen	1134-47-0	ADReCS
Balsalazide	80573-04-2	MetaADEDB
Benazepril	86541-75-5	MetaADEDB
Bendamustine	16506-27-7	MetaADEDB
benfluorex	23602-78-0	MetaADEDB
Benzatropine	86-13-5	MetaADEDB
Benzonatate	104-31-4	MetaADEDB
beta-Cyclodextrins	7585-39-9	MetaADEDB
betamethasone dipropionate	5593-20-4	MetaADEDB
Betaxolol	63659-18-7	ADReCS
Bethanechol	674-38-4	MetaADEDB
Bexarotene	153559-49-0	ADReCS
Bicalutamide	90357-06-5	MetaADEDB
Bimatoprost	155206-00-1	MetaADEDB
Biotin	58-85-5	MetaADEDB
Bisacodyl	603-50-9	MetaADEDB
bismuth subsalicylate	14882-18-9	MetaADEDB
Bortezomib	179324-69-7	ADReCS
Brimonidine	59803-98-4	ADReCS
Budesonide	51333-22-3	MetaADEDB
Bumetanide	28395-03-1	MetaADEDB
Bupivacaine	2180-92-9	ADReCS
Buprenorphine	52485-79-7	ADReCS
Bupropion	34841-39-9	ADReCS
Buspirone	36505-84-7	ADReCS
Butalbital	77-26-9	MetaADEDB
Butorphanol	42408-82-2	ADReCS
Calcipotriol	112965-21-6	MetaADEDB
Calcium	7440-70-2	MetaADEDB
Candesartan	139481-59-7	ADReCS
Candesartan cilexetil	145040-37-5	MetaADEDB
Capecitabine	154361-50-9	ADReCS
Capsaicin	404-86-4	MetaADEDB
Carbamazepine	298-46-4	ADReCS
Carbidopa	28860-95-9	MetaADEDB
Carboplatin	41575-94-4	MetaADEDB
Carisoprodol	78-44-4	MetaADEDB
Carvedilol	72956-09-3	MetaADEDB
Cefaclor	53994-73-3	MetaADEDB
Cefadroxil	66592-87-8	MetaADEDB
Cefazolin	25953-19-9	MetaADEDB
Cefditoren	104145-95-1	MetaADEDB
cefditoren pivoxil	117467-28-4	MetaADEDB
Cefepime	88040-23-7	MetaADEDB
Cefoxitin	35607-66-0	MetaADEDB
Cefprozil	92665-29-7	MetaADEDB
Ceftriaxone	73384-59-5	MetaADEDB
Cefuroxime	55268-75-2	MetaADEDB
Cefuroxime axetil	64544-07-6	MetaADEDB
Celecoxib	169590-42-5	ADReCS
Cephalexin	15686-71-2	ADReCS
Cerivastatin	145599-86-6	MetaADEDB
Cetirizine	83881-51-0	ADReCS
Cevimeline	107233-08-9	ADReCS
Chlordiazepoxide	58-25-3	MetaADEDB
Chlorhexidine	55-56-1	ADReCS
Chlorhexidine gluconate	18472-51-0	MetaADEDB
Chlorthalidone	77-36-1	MetaADEDB
Cholesterol	57-88-5	MetaADEDB
Cidofovir	113852-37-2	ADReCS
Cimetidine	51481-61-9	MetaADEDB
Cinacalcet	226256-56-0	MetaADEDB
Ciprofloxacin	85721-33-1	ADReCS
Cisapride	81098-60-4	MetaADEDB
Citalopram	59729-33-8	ADReCS
Clindamycin	18323-44-9	MetaADEDB
Clobazam	22316-47-8	ADReCS
Clobetasol propionate	25122-46-7	MetaADEDB
Clomipramine	303-49-1	ADReCS
Clonazepam	1622-61-3	ADReCS
Clopidogrel	113665-84-2	ADReCS
Clotrimazole	23593-75-1	MetaADEDB
Clozapine	5786-21-0	ADReCS
Codeine	76-57-3	MetaADEDB
coenzyme Q10	303-98-0	MetaADEDB
Colistin	1264-72-8	ADReCS
Conjugated Estrogens	438-67-5	ADReCS
Cortisone	53-06-5	MetaADEDB
Cortisone acetate	50-04-4	MetaADEDB
Cyclobenzaprine	303-53-7	ADReCS
Cyclopentolate	512-15-2	MetaADEDB
Cycloserine	68-41-7	ADReCS
Cyclosporine	59865-13-3	ADReCS
Cyproheptadine	129-03-3	MetaADEDB
Dexamethasone	50-02-2	ADReCS
Diazepam	439-14-5	ADReCS
Diclofenac	15307-86-5	ADReCS
Dicloxacillin	3116-76-5	MetaADEDB
Dicyclomine	77-19-0	MetaADEDB
Diflunisal	22494-42-4	MetaADEDB
Diltiazem	42399-41-7	ADReCS
diphenoxylate	915-30-0	MetaADEDB
Disulfiram	97-77-8	MetaADEDB
Divalproex Sodium	76584-70-8	ADReCS
Docetaxel	114977-28-5	MetaADEDB
docusate	577-11-7	MetaADEDB
Dolasetron	115956-12-2	MetaADEDB
Donepezil	120014-06-4	ADReCS
Doxepin	1668-19-5	MetaADEDB
Doxorubicin	23214-92-8	MetaADEDB
Doxycycline	564-25-0	MetaADEDB
Droperidol	548-73-2	MetaADEDB
duloxetine	136434-34-9	SIDER
ebastine	90729-43-4	MetaADEDB
Econazole	27220-47-9	MetaADEDB
Eflornithine Hydrochloride	62878-23-9	ADReCS
Eletriptan	143322-58-1	ADReCS
Enoxaparin	9005-49-6	MetaADEDB
Ephedrine	299-42-3	MetaADEDB
Epoprostenol	35121-78-9	ADReCS
Eprosartan	133040-01-4	ADReCS
Erythromycin	114-07-8	MetaADEDB
Esmolol	100286-90-6	ADReCS
Estradiol	50-28-2	ADReCS
Estramustine	2998-57-4	MetaADEDB
Estrogens Conjugated Synthetic A	12126-59-9	MetaADEDB
Eszopiclone	138729-47-2	ADReCS
Etidronic acid	7414-83-7	ADReCS
Etodolac	41340-25-4	MetaADEDB
Etomidate	33125-97-2	MetaADEDB
Exemestane	107868-30-4	ADReCS
Famciclovir	104227-87-4	MetaADEDB
Famotidine	76824-35-6	MetaADEDB
Felbamate	25451-15-4	ADReCS
Fenofibrate	49562-28-9	ADReCS
Fenoprofen	34597-40-5	MetaADEDB
Fentanyl	437-38-7	ADReCS
Fexofenadine	83799-24-0	MetaADEDB
Fioricet	122018-95-5	MetaADEDB
Fludrocortisone	127-31-1	MetaADEDB
Fludrocortisone acetate	514-36-3	MetaADEDB
Fluocinolone Acetonide	67-73-2	MetaADEDB
Fluocinonide	356-12-7	MetaADEDB
Fluorouracil	51-21-8	ADReCS
Fluoxetine	54910-89-3	ADReCS
Flupirtine	56995-20-1	MetaADEDB
Flurazepam	17617-23-1	ADReCS
Flurbiprofen	5104-49-4	ADReCS
Flutamide	13311-84-7	MetaADEDB
Fluticasone Propionate	80474-14-2	MetaADEDB
Fluvastatin	93957-54-1	ADReCS
Fluvoxamine	54739-18-3	ADReCS
Fosinopril	98048-97-6	MetaADEDB
Fosphenytoin	93390-81-9	ADReCS
Frovatriptan	158747-02-5	ADReCS
Fulvestrant	129453-61-8	MetaADEDB
Gabapentin	60142-96-3	ADReCS
gadolinium	7440-54-2	MetaADEDB
Gadoversetamide	131069-91-5	MetaADEDB
Gatifloxacin	112811-59-3	MetaADEDB
Gemcitabine	95058-81-4	MetaADEDB
Gemfibrozil	25812-30-0	MetaADEDB
Gliclazide	21187-98-4	ADReCS
Glimepiride	93479-97-1	MetaADEDB
Glipizide	29094-61-9	MetaADEDB
Glutamine	56-85-9	MetaADEDB
Goserelin	65807-02-5	ADReCS
Granisetron	109889-09-0	MetaADEDB
Guanfacine	29110-47-2	MetaADEDB
Halobetasol Propionate	66852-54-8	MetaADEDB
haloperidol decanoate	74050-97-8	MetaADEDB
human insulin	11061-68-0	ADReCS
hyaluronic acid	9004-61-9	MetaADEDB
Hydralazine	86-54-4	MetaADEDB
Hydrochlorothiazide	58-93-5	MetaADEDB
hydrocodone	125-29-1	MetaADEDB
Hydrocortisone	50-23-7	ADReCS
Hydromorphone	466-99-9	ADReCS
Hydroxychloroquine	118-42-3	MetaADEDB
Hydroxyzine	68-88-2	MetaADEDB
Hyoscyamine	101-31-5	ADReCS
Ibandronate	114084-78-5	ADReCS
Ibritumomab	174722-31-7	PROTECT
Ibuprofen	15687-27-1	ADReCS
Imipramine	50-49-7	MetaADEDB
Indapamide	26807-65-8	ADReCS
Indinavir	150378-17-9	MetaADEDB
Indomethacin	53-86-1	ADReCS
Indoprofen	31842-01-0	MetaADEDB
Interferon Alfa-2a Recombinant	76543-88-9	ADReCS
Ipratropium bromide	22254-24-6	MetaADEDB
Iron	7439-89-6	MetaADEDB
Isosorbide	652-67-5	ADReCS
Isosorbide Mononitrate	16051-77-7	MetaADEDB
Isradipine	75695-93-1	MetaADEDB
Itraconazole	84625-61-6	MetaADEDB
Ketamine	6740-88-1	MetaADEDB
Ketoconazole	65277-42-1	MetaADEDB
Ketoprofen	22071-15-4	MetaADEDB
Ketorolac	66635-83-4	MetaADEDB
ketorolac tromethamine	74103-07-4	MetaADEDB
Ketotifen	34580-14-8	MetaADEDB
Labetalol	36894-69-6	MetaADEDB
Lacosamide	175481-36-4	ADReCS
Lactulose	4618-18-2	MetaADEDB
Lamotrigine	84057-84-1	ADReCS
Lansoprazole	103577-45-3	ADReCS
Leflunomide	75706-12-6	ADReCS
Lenalidomide	191732-72-6	ADReCS
Letrozole	112809-51-5	MetaADEDB
Leuprolide	53714-56-0	ADReCS
Leuprolide acetate	74381-53-6	SIDER
Levothyroxine	51-48-9	MetaADEDB
Lidocaine	137-58-6	ADReCS
Linezolid	165800-03-3	MetaADEDB
Lisinopril	83915-83-7	MetaADEDB
Lithium	7439-93-2	ADReCS
Lithium Carbonate	554-13-2	MetaADEDB
Lomotil	55840-97-6	MetaADEDB
Lomustine	13010-47-4	ADReCS
Loratadine	79794-75-5	MetaADEDB
Lorazepam	846-49-1	ADReCS
Losartan	114798-26-4	MetaADEDB
Lovastatin	75330-75-5	MetaADEDB
Lycopene	502-65-8	MetaADEDB
magnesium citrate	7779-25-1	MetaADEDB
Medroxyprogesterone	520-85-4	ADReCS
Mefenamic acid	61-68-7	MetaADEDB
Megestrol	3562-63-8	MetaADEDB
Meloxicam	71125-38-7	ADReCS
Melphalan	148-82-3	MetaADEDB
Memantine	19982-08-2	MetaADEDB
Mephenytoin	50-12-4	ADReCS
Mepivacaine	96-88-8	MetaADEDB
Meprobamate	57-53-4	ADReCS
Mesalazine	89-57-6	ADReCS
Mesoridazine	5588-33-0	ADReCS
Metaxalone	1665-48-1	MetaADEDB
Methadone	76-99-3	MetaADEDB
Methamphetamine	537-46-2	MetaADEDB
Methocarbamol	532-03-6	MetaADEDB
Methotrexate	59-05-2	ADReCS
Methylnaltrexone	73232-52-7	ADReCS
Methylphenidate	113-45-1	MetaADEDB
Methylprednisolone	83-43-2	ADReCS
methylprednisolone acetate	53-36-1	MetaADEDB
Methyltestosterone	58-18-4	MetaADEDB
Metolazone	17560-51-9	ADReCS
Metoprolol	37350-58-6	MetaADEDB
Metronidazole	443-48-1	ADReCS
mianserin	24219-97-4	MetaADEDB
Midazolam	59467-70-8	ADReCS
Midodrine	133163-28-7	MetaADEDB
Minocycline	10118-90-8	MetaADEDB
Minoxidil	38304-91-5	MetaADEDB
Mirabegron	223673-61-8	ADReCS
Mirtazapine	61337-67-5	ADReCS
Misoprostol	59122-46-2	MetaADEDB
Mitoxantrone	65271-80-9	MetaADEDB
Modafinil	68693-11-8	ADReCS
Moexipril	103775-10-6	MetaADEDB
Mometasone	105102-22-5	MetaADEDB
montelukast sodium	151767-02-1	MetaADEDB
Morphine	57-27-2	ADReCS
Moxifloxacin	151096-09-2	ADReCS
Mupirocin	12650-69-0	MetaADEDB
Mycophenolic acid	24280-93-1	ADReCS
Nabumetone	42924-53-8	MetaADEDB
Nadolol	42200-33-9	ADReCS
Nalbuphine	20594-83-6	MetaADEDB
Naloxone	465-65-6	MetaADEDB
Naproxen	22204-53-1	ADReCS
Nateglinide	105816-04-4	ADReCS
Nefazodone	83366-66-9	ADReCS
Nelarabine	121032-29-9	ADReCS
Neomycin	1404-04-2	MetaADEDB
Neostigmine	59-99-4	ADReCS
Nevirapine	129618-40-2	MetaADEDB
Nifedipine	21829-25-4	ADReCS
Nimesulide	51803-78-2	MetaADEDB
Nisoldipine	63675-72-9	MetaADEDB
Nitrofurantoin	67-20-9	MetaADEDB
Nizatidine	76963-41-2	MetaADEDB
Nortriptyline	72-69-5	MetaADEDB
Nystatin	1400-61-9	MetaADEDB
Octreotide	83150-76-9	ADReCS
Ofloxacin	82419-36-1	MetaADEDB
Olanzapine	132539-06-1	ADReCS
Olsalazine	15722-48-2	MetaADEDB
Omeprazole	73590-58-6	ADReCS
Ondansetron	99614-02-5	MetaADEDB
Orlistat	96829-58-2	ADReCS
Orphenadrine	83-98-7	MetaADEDB
Oxaliplatin	61825-94-3	ADReCS
Oxaprozin	21256-18-8	MetaADEDB
Oxazepam	604-75-1	ADReCS
Oxcarbazepine	28721-07-5	MetaADEDB
Oxybutynin	5633-20-5	ADReCS
oxymetazoline	1491-59-4	MetaADEDB
Paclitaxel	33069-62-4	MetaADEDB
Paliperidone	144598-75-4	ADReCS
Pamidronate	40391-99-9	ADReCS
Pantoprazole	102625-70-7	ADReCS
Paricalcitol	131918-61-1	ADReCS
Paroxetine	61869-08-7	ADReCS
Penicillin v	87-08-1	MetaADEDB
Pentostatin	53910-25-1	ADReCS
Perphenazine	58-39-9	ADReCS
Pethidine	57-42-1	MetaADEDB
Phenazopyridine	94-78-0	MetaADEDB
Phenelzine	51-71-8	MetaADEDB
Phenolphthalein	77-09-8	MetaADEDB
Phentermine	122-09-8	MetaADEDB
Phenylbutazone	50-33-9	MetaADEDB
Phenytoin	57-41-0	ADReCS
Pilocarpine	92-13-7	MetaADEDB
Pimecrolimus	137071-32-0	MetaADEDB
Piracetam	7491-74-9	MetaADEDB
Piroxicam	36322-90-4	MetaADEDB
Polyethylene Glycol	25322-68-3	MetaADEDB
Posaconazole	171228-49-2	MetaADEDB
Pramipexole	104632-26-0	ADReCS
Pravastatin	81093-37-0	MetaADEDB
Prednisolone	50-24-8	ADReCS
Prednisolone acetate	52-21-1	MetaADEDB
Pregabalin	148553-50-8	ADReCS
Primidone	125-33-7	MetaADEDB
Procarbazine	671-16-9	ADReCS
Procaterol	59828-07-8	MetaADEDB
Prochlorperazine edisylate	1257-78-9	MetaADEDB
Progesterone	57-83-0	ADReCS
Promethazine	60-87-7	MetaADEDB
Propafenone	54063-53-5	ADReCS
Propoxyphene	469-62-5	MetaADEDB
Propoxyphene napsylate	17140-78-2	MetaADEDB
Pyrazinamide	98-96-4	MetaADEDB
Pyridoxine	65-23-6	MetaADEDB
Quetiapine	111974-69-7	ADReCS
Quinapril	85441-61-8	MetaADEDB
Quinidine	56-54-2	MetaADEDB
Rabeprazole	117976-89-3	ADReCS
Rasagiline	136236-51-6	ADReCS
Remifentanil	132875-61-7	MetaADEDB
Rifapentine	61379-65-5	ADReCS
Riluzole	1744-22-5	ADReCS
Risedronate	105462-24-6	ADReCS
Risperidone	106266-06-2	ADReCS
Ritonavir	155213-67-5	ADReCS
Rivaroxaban	366789-02-8	MetaADEDB
Rivastigmine	123441-03-2	ADReCS
Rizatriptan	145202-66-0	ADReCS
Rofecoxib	162011-90-7	ADReCS
Ropinirole	91374-21-9	ADReCS
rosuvastatin calcium	147098-20-2	MetaADEDB
Salbutamol	18559-94-9	MetaADEDB
Salmeterol	89365-50-4	MetaADEDB
Salmon Calcitonin	47931-85-1	ADReCS
Saquinavir	127779-20-8	ADReCS
scopolamine	51-34-3	MetaADEDB
Selegiline	14611-51-9	ADReCS
selenium	7782-49-2	MetaADEDB
Sertraline	79617-96-2	ADReCS
Sevelamer	152751-57-0	MetaADEDB
Sibutramine	106650-56-0	ADReCS
Sildenafil	139755-83-2	ADReCS
Silver sulfadiazine	22199-08-2	MetaADEDB
Sirolimus	53123-88-9	ADReCS
Sitagliptin	486460-32-6	ADReCS
Sitaxentan	210421-64-0	MetaADEDB
Sodium bicarbonate	144-55-8	MetaADEDB
Solifenacin	242478-37-1	MetaADEDB
Somatropin recombinant	12629-01-5	PROTECT
Spironolactone	52-01-7	MetaADEDB
Streptomycin	57-92-1	MetaADEDB
Succinylcholine	306-40-1	MetaADEDB
Sucralfate	54182-58-0	MetaADEDB
sulbactam	94935-63-4	MetaADEDB
sulfamethoxazole	723-46-6	MetaADEDB
Sulindac	38194-50-2	MetaADEDB
Sumatriptan	103628-46-2	ADReCS
Tacrine	321-64-2	ADReCS
Tacrolimus	104987-11-3	ADReCS
Tadalafil	171596-29-5	MetaADEDB
Tamoxifen	10540-29-1	ADReCS
Tapentadol	175591-23-8	SIDER
Tazarotene	118292-40-3	MetaADEDB
Tegaserod	189188-57-6	ADReCS
Telmisartan	144701-48-4	ADReCS
Temazepam	846-50-4	MetaADEDB
Terazosin	63590-64-7	ADReCS
Terbinafine	91161-71-6	MetaADEDB
Terconazole	67915-31-5	MetaADEDB
Testosterone	58-22-0	MetaADEDB
Testosterone cypionate	58-20-8	MetaADEDB
Tetrabenazine	58-46-8	ADReCS
Tetracycline	60-54-8	ADReCS
Thalidomide	50-35-1	ADReCS
Theophylline	58-55-9	MetaADEDB
Thiethylperazine	1420-55-9	MetaADEDB
Thyrotropin Releasing Hormone	24305-27-9	ADReCS
Tiagabine	115103-54-3	ADReCS
Ticarcillin	34787-01-4	MetaADEDB
Ticlopidine	55142-85-3	ADReCS
Tigecycline	220620-09-7	MetaADEDB
Tiludronate	89987-06-4	ADReCS
Timolol	26839-75-8	MetaADEDB
Tiotropium	186691-13-4	MetaADEDB
Tizanidine	51322-75-9	MetaADEDB
Tobramycin	32986-56-4	MetaADEDB
Tolcapone	134308-13-7	ADReCS
Tolmetin	26171-23-3	MetaADEDB
Tolterodine	124937-51-5	MetaADEDB
Topiramate	97240-79-4	ADReCS
Tramadol	27203-92-5	ADReCS
Trandolapril	87679-37-6	ADReCS
Travoprost	157283-68-6	MetaADEDB
Trazodone	19794-93-5	ADReCS
Tretinoin	302-79-4	MetaADEDB
Triamcinolone	124-94-7	ADReCS
Triamcinolone acetonide	76-25-5	MetaADEDB
Triamterene	396-01-0	MetaADEDB
Triazolam	28911-01-5	ADReCS
Trichlormethiazide	133-67-5	MetaADEDB
Trimethobenzamide	138-56-7	MetaADEDB
Trimethoprim	738-70-5	ADReCS
Trospium	10405-02-4	MetaADEDB
Trovafloxacin	147059-72-1	ADReCS
Urofollitropin	146479-72-3	ADReCS
Valaciclovir	124832-26-4	ADReCS
valacyclovir	124832-27-5	MetaADEDB
Valproic Acid	99-66-1	ADReCS
Valsartan	137862-53-4	MetaADEDB
Vancomycin	1404-90-6	MetaADEDB
Varenicline	249296-44-4	ADReCS
Venlafaxine	93413-69-5	ADReCS
Verteporfin	129497-78-5	ADReCS
Vigabatrin	60643-86-9	ADReCS
Vincristine	57-22-7	MetaADEDB
Vinorelbine	71486-22-1	MetaADEDB
Voriconazole	137234-62-9	MetaADEDB
Warfarin	81-81-2	MetaADEDB
Zafirlukast	107753-78-6	MetaADEDB
Zalcitabine	7481-89-2	ADReCS
Zaleplon	151319-34-5	ADReCS
Ziconotide	107452-89-1	ADReCS
zinc	7440-66-6	MetaADEDB
Ziprasidone	146939-27-7	ADReCS
Zoledronate	118072-93-8	ADReCS
Zolmitriptan	139264-17-8	ADReCS
Zolpidem	82626-48-0	ADReCS
Zonisamide	68291-97-4	ADReCS
Zopiclone	43200-80-2	ADReCS

List of proteins causing Osteoarthritis
Protein Name	Uniprot ID	Source