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Enter Adverse Drug Reaction Name:
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Drugs Causing Necrosis: 366
Drug Name
CAS Number
Source
Acenocoumarol
152-72-7
MetaADEDB
Acetaldehyde
75-07-0
MetaADEDB
Acetaminophen
103-90-2
MetaADEDB
Acetazolamide
59-66-5
ADReCS
Acetic acid
64-19-7
MetaADEDB
Acetylcysteine
616-91-1
MetaADEDB
Acetylsalicylic acid
50-78-2
MetaADEDB
Aciclovir
59277-89-3
ADReCS
Aclarubicin
57576-44-0
MetaADEDB
Acrolein
107-02-8
MetaADEDB
Adenosine
58-61-7
MetaADEDB
Albendazole
54965-21-8
MetaADEDB
Allopurinol
315-30-0
ADReCS
Alprazolam
28981-97-7
MetaADEDB
Alprostadil
745-65-3
MetaADEDB
Amifostine
20537-88-6
MetaADEDB
Aminocaproic Acid
60-32-2
ADReCS
Aminolevulinic acid
106-60-5
MetaADEDB
Amiodarone
1951-25-3
ADReCS
Amitriptyline Hydrochloride
549-18-8
MetaADEDB
Amphotericin B
1397-89-3
MetaADEDB
Amrinone
60719-84-8
ADReCS
Amsacrine
51264-14-3
ADReCS
Anidulafungin
166663-25-8
ADReCS
Aprotinin
9087-70-1
ADReCS
Arginine
74-79-3
ADReCS
Atropine
51-55-8
MetaADEDB
Auranofin
34031-32-8
MetaADEDB
Aurothioglucose
12192-57-3
MetaADEDB
Azathioprine
446-86-6
MetaADEDB
Azithromycin
83905-01-5
ADReCS
Balsalazide
80573-04-2
ADReCS
Bendamustine
16506-27-7
ADReCS
Benzene
71-43-2
MetaADEDB
Benzylpenicillin
61-33-6
ADReCS
Betamethasone
378-44-9
MetaADEDB
Bezafibrate
41859-67-0
MetaADEDB
Bilirubin
635-65-4
MetaADEDB
Bromcresol Green
76-60-8
MetaADEDB
Bromodeoxyuridine
59-14-3
MetaADEDB
Budesonide
51333-22-3
ADReCS
Bupivacaine
2180-92-9
MetaADEDB
Buprenorphine
52485-79-7
MetaADEDB
Busulfan
55-98-1
ADReCS
Buthionine Sulfoximine
5072-26-4
MetaADEDB
Cadmium
7440-43-9
MetaADEDB
Caffeine
58-08-2
MetaADEDB
Calcium
7440-70-2
ADReCS
Capsaicin
404-86-4
MetaADEDB
Captopril
62571-86-2
ADReCS
Carboplatin
41575-94-4
ADReCS
Carmustine
154-93-8
ADReCS
Cephaloridine
50-59-9
MetaADEDB
Cerivastatin
145599-86-6
ADReCS
Cevimeline
107233-08-9
ADReCS
Chloroform
67-66-3
MetaADEDB
Chloroquine
54-05-7
MetaADEDB
Chlorphenamine
132-22-9
MetaADEDB
Chlorpromazine
50-53-3
MetaADEDB
Cholesterol
57-88-5
MetaADEDB
Cidofovir
113852-37-2
ADReCS
Cilazapril
92077-78-6
SIDER
Cimetidine
51481-61-9
MetaADEDB
Ciprofloxacin
85721-33-1
ADReCS
Cisplatin
15663-27-1
ADReCS
Citalopram
59729-33-8
ADReCS
Cladribine
4291-63-8
MetaADEDB
Clarithromycin
81103-11-9
ADReCS
Clodronic Acid
22560-50-5
MetaADEDB
Clofibrate
637-07-0
MetaADEDB
Clopidogrel
113665-84-2
ADReCS
Clorazepate Dipotassium
57109-90-7
MetaADEDB
Clozapine
5786-21-0
MetaADEDB
Cocaine
50-36-2
MetaADEDB
Colchicine
64-86-8
MetaADEDB
Copper
7440-50-8
MetaADEDB
Corticotropin
12427-33-7
ADReCS
Cortisone
53-06-5
ADReCS
Curcumin
458-37-7
MetaADEDB
Cycloheximide
66-81-9
MetaADEDB
Cyclophosphamide
50-18-0
ADReCS
Cyclosporine
59865-13-3
ADReCS
Cyproterone
2098-66-0
ADReCS
Cytarabine
147-94-4
MetaADEDB
Cytosine
71-30-7
ADReCS
Dantrolene
7261-97-4
ADReCS
Dapsone
80-08-0
ADReCS
Darunavir
206361-99-1
ADReCS
Daunorubicin
20830-81-3
ADReCS
Deferoxamine
70-51-9
MetaADEDB
Delavirdine
136817-59-9
ADReCS
Deoxycholic Acid
83-44-3
MetaADEDB
Deoxythymidine
50-89-5
MetaADEDB
Desflurane
57041-67-5
ADReCS
Desirudin
120993-53-5
ADReCS
Dexamethasone
50-02-2
ADReCS
Diatrizoate
117-96-4
ADReCS
Diazoxide
364-98-7
ADReCS
Diclofenac
15307-86-5
ADReCS
Dicyclomine
77-19-0
ADReCS
Digoxin
20830-75-5
ADReCS
dihydroergotamine
6190-39-2
MetaADEDB
Diltiazem
42399-41-7
MetaADEDB
Dimethylnitrosamine
62-75-9
MetaADEDB
Diphenhydramine
58-73-1
MetaADEDB
Disulfiram
97-77-8
MetaADEDB
Diuron
330-54-1
MetaADEDB
Dizocilpine Maleate
77086-22-7
MetaADEDB
Dobutamine
34368-04-2
ADReCS
Docetaxel
114977-28-5
ADReCS
Doxorubicin
23214-92-8
ADReCS
Edetic Acid
62-33-9
ADReCS
Efavirenz
154598-52-4
ADReCS
Enalapril
75847-73-3
MetaADEDB
Enflurane
13838-16-9
ADReCS
Enfuvirtide
159519-65-0
ADReCS
Enoxaparin
9005-49-6
ADReCS
Ephedrine
299-42-3
MetaADEDB
Epinephrine
51-43-4
ADReCS
Epoprostenol
35121-78-9
MetaADEDB
Ertapenem
153832-46-3
ADReCS
Esmolol
100286-90-6
ADReCS
Ethanolamine
141-43-5
ADReCS
ethylenediaminetetraacetic acid
60-00-4
SIDER
Etodolac
41340-25-4
ADReCS
Etoposide
33419-42-0
ADReCS
Felbamate
25451-15-4
ADReCS
Fenoldopam
67227-57-0
SIDER
Fenoprofen
34597-40-5
SIDER
Fentanyl
437-38-7
MetaADEDB
Fluconazole
86386-73-4
ADReCS
Flucytosine
2022-85-7
ADReCS
Fludrocortisone
127-31-1
ADReCS
Fluorouracil
51-21-8
ADReCS
Fluoxetine
54910-89-3
ADReCS
Flutamide
13311-84-7
ADReCS
Fluvastatin
93957-54-1
ADReCS
Formaldehyde
50-00-0
MetaADEDB
Fosfomycin
23155-02-4
ADReCS
Furosemide
54-31-9
MetaADEDB
Gabapentin
60142-96-3
ADReCS
Gadobenate Dimeglumine
113662-23-0
ADReCS
Galactosamine
7535-00-4
MetaADEDB
Galactose
10257-28-0
ADReCS
Gallopamil
16662-46-7
MetaADEDB
Gemcitabine
95058-81-4
ADReCS
Genistein
446-72-0
MetaADEDB
Gentamicin
1403-66-3
ADReCS
Glatiramer Acetate
147245-92-9
ADReCS
Glyburide
10238-21-8
MetaADEDB
Goserelin
65807-02-5
ADReCS
Haloperidol
52-86-8
MetaADEDB
Halothane
151-67-7
ADReCS
heroin
561-27-3
MetaADEDB
Hydralazine
86-54-4
MetaADEDB
Hydrocortisone
50-23-7
ADReCS
Hydrogen Peroxide
7722-84-1
MetaADEDB
Hydroxyurea
127-07-1
ADReCS
Ibuprofen
15687-27-1
ADReCS
Idarubicin
58957-92-9
MetaADEDB
Ifosfamide
3778-73-2
ADReCS
iloprost
78919-13-8
MetaADEDB
Imatinib
152459-95-5
ADReCS
Imipramine
50-49-7
MetaADEDB
Indapamide
26807-65-8
MetaADEDB
Indomethacin
53-86-1
MetaADEDB
Iodine
7553-56-2
MetaADEDB
Iopamidol
60166-93-0
ADReCS
Iopromide
73334-07-3
ADReCS
Iothalamate Meglumine
13087-53-1
ADReCS
Iothalamate Sodium
1225-20-3
ADReCS
Ioversol
87771-40-2
ADReCS
Ioxaglate
59017-64-0
ADReCS
Ioxaglate Meglumine
59018-13-2
ADReCS
Iproniazid
54-92-2
MetaADEDB
Isoflurane
26675-46-7
ADReCS
Isoflurophate
55-91-4
MetaADEDB
Isoniazid
54-85-3
MetaADEDB
Isoprenaline
7683-59-2
MetaADEDB
Isoxsuprine
395-28-8
MetaADEDB
Itraconazole
84625-61-6
MetaADEDB
Kainic Acid
487-79-6
MetaADEDB
Ketamine
6740-88-1
MetaADEDB
Ketoprofen
22071-15-4
ADReCS
Ketorolac
66635-83-4
ADReCS
Ketotifen
34580-14-8
MetaADEDB
Labetalol
36894-69-6
ADReCS
Leflunomide
75706-12-6
ADReCS
Levamisole
14769-73-4
MetaADEDB
Levodopa
59-92-7
MetaADEDB
Levomepromazine
60-99-1
MetaADEDB
Levothyroxine
51-48-9
MetaADEDB
Lidocaine
137-58-6
MetaADEDB
Lindane
58-89-9
MetaADEDB
Lithium
7439-93-2
MetaADEDB
Lomefloxacin
98079-51-7
ADReCS
Losartan
114798-26-4
MetaADEDB
Lovastatin
75330-75-5
ADReCS
Mannitol
69-65-8
ADReCS
Medroxyprogesterone
520-85-4
ADReCS
Mefenamic acid
61-68-7
ADReCS
melatonin
73-31-4
MetaADEDB
Melphalan
148-82-3
ADReCS
Memantine
19982-08-2
ADReCS
Mesalazine
89-57-6
ADReCS
Methadone
76-99-3
MetaADEDB
Methamphetamine
537-46-2
MetaADEDB
Methazolamide
554-57-4
ADReCS
Methimazole
60-56-0
MetaADEDB
Methiothepin
20229-30-5
MetaADEDB
Methotrexate
59-05-2
ADReCS
Methoxamine
390-28-3
MetaADEDB
Methoxyflurane
76-38-0
MetaADEDB
Methylcholanthrene
56-49-5
MetaADEDB
Methyldopa
555-30-6
MetaADEDB
Methylprednisolone
83-43-2
ADReCS
Methysergide
361-37-5
MetaADEDB
Metolazone
17560-51-9
ADReCS
Mexiletine
31828-71-4
ADReCS
Micafungin
235114-32-6
ADReCS
Midazolam
59467-70-8
ADReCS
Minocycline
10118-90-8
MetaADEDB
Minoxidil
38304-91-5
MetaADEDB
Mitomycin
50-07-7
ADReCS
Mitotane
53-19-0
MetaADEDB
Mitoxantrone
65271-80-9
ADReCS
Morphine
57-27-2
ADReCS
Mycophenolic acid
24280-93-1
ADReCS
Naloxone
465-65-6
MetaADEDB
Naproxen
22204-53-1
ADReCS
Nefazodone
83366-66-9
ADReCS
Nelfinavir
159989-64-7
MetaADEDB
Neomycin
1404-04-2
MetaADEDB
Nevirapine
129618-40-2
ADReCS
Niacin
59-67-6
MetaADEDB
Nicotine
54-11-5
MetaADEDB
Nifedipine
21829-25-4
MetaADEDB
Nimodipine
66085-59-4
MetaADEDB
Nimustine
42471-28-3
MetaADEDB
Nitric Oxide
10102-43-9
MetaADEDB
Nitrofurantoin
67-20-9
ADReCS
Norepinephrine
51-41-2
ADReCS
Norfloxacin
70458-96-7
MetaADEDB
Nortriptyline
72-69-5
ADReCS
Octreotide
83150-76-9
MetaADEDB
Ofloxacin
82419-36-1
ADReCS
Olsalazine
15722-48-2
ADReCS
Omeprazole
73590-58-6
ADReCS
Ondansetron
99614-02-5
ADReCS
Ouabain
630-60-4
MetaADEDB
Oxaliplatin
61825-94-3
ADReCS
Oxandrolone
53-39-4
ADReCS
Oxidopamine
1199-18-4
MetaADEDB
Oxycodone
76-42-6
MetaADEDB
Oxymetholone
434-07-1
ADReCS
Paclitaxel
33069-62-4
ADReCS
Pancuronium
15500-66-0
MetaADEDB
Paraoxon
311-45-5
MetaADEDB
Paroxetine
61869-08-7
ADReCS
Pemoline
2152-34-3
MetaADEDB
Pentagastrin
5534-95-2
MetaADEDB
Pentamidine
100-33-4
ADReCS
Peroxynitrous Acid
14691-52-2
MetaADEDB
Phenacetin
62-44-2
MetaADEDB
Phenelzine
51-71-8
MetaADEDB
Phenobarbital
50-06-6
MetaADEDB
Phenoxybenzamine
59-96-1
MetaADEDB
Phenprocoumon
435-97-2
MetaADEDB
Phentolamine
50-60-2
MetaADEDB
Phenylbutazone
50-33-9
MetaADEDB
Phenylephrine
59-42-7
MetaADEDB
Phenytoin
57-41-0
ADReCS
Pilocarpine
92-13-7
MetaADEDB
Piroxicam
36322-90-4
ADReCS
Polidocanol
9002-92-0
ADReCS
Porfimer
87806-31-3
ADReCS
Porfimer sodium
97067-70-4
SIDER
Pravastatin
81093-37-0
ADReCS
Prednisolone
50-24-8
ADReCS
Prednisone
53-03-2
ADReCS
Pregabalin
148553-50-8
ADReCS
Probenecid
57-66-9
ADReCS
Procainamide
51-06-9
MetaADEDB
Procaine
59-46-1
MetaADEDB
Progesterone
57-83-0
ADReCS
Promethazine
60-87-7
ADReCS
Propantheline
298-50-0
MetaADEDB
Proparacaine
499-67-2
ADReCS
Propofol
2078-54-8
MetaADEDB
Propranolol
525-66-6
MetaADEDB
Propylthiouracil
51-52-5
MetaADEDB
Pyridoxine
65-23-6
MetaADEDB
Pyrimethamine
58-14-0
MetaADEDB
Quercetin
117-39-5
MetaADEDB
Quinidine
56-54-2
ADReCS
Quinine
130-95-0
MetaADEDB
Raltitrexed
112887-68-0
ADReCS
Ramipril
87333-19-5
ADReCS
Rasagiline
136236-51-6
ADReCS
Ribavirin
36791-04-5
MetaADEDB
Rifampicin
13292-46-1
ADReCS
Riluzole
1744-22-5
ADReCS
Risperidone
106266-06-2
ADReCS
Ropinirole
91374-21-9
ADReCS
Rotenone
83-79-4
MetaADEDB
S-Adenosylmethionine
29908-03-0
MetaADEDB
Saquinavir
127779-20-8
MetaADEDB
selenium
7782-49-2
MetaADEDB
Sevoflurane
28523-86-6
ADReCS
Silver sulfadiazine
22199-08-2
ADReCS
Simvastatin
79902-63-9
ADReCS
Sinecatechins
811420-59-4
ADReCS
Sirolimus
53123-88-9
ADReCS
Sitaxentan
210421-64-0
MetaADEDB
Sodium Azide
26628-22-8
MetaADEDB
Sodium bicarbonate
144-55-8
ADReCS
Sodium Iodide
7681-82-5
MetaADEDB
Sodium Polystyrene Sulfonate
25704-18-1
ADReCS
Spermine
71-44-3
MetaADEDB
Streptozocin
18883-66-4
ADReCS
Succinylcholine
306-40-1
MetaADEDB
Sulfacetamide
144-80-9
ADReCS
Sulfasalazine
599-79-1
ADReCS
Sulfisoxazole
127-69-5
ADReCS
sunitinib
557795-19-4
SIDER
Tacrine
321-64-2
ADReCS
Tacrolimus
104987-11-3
ADReCS
Tamoxifen
10540-29-1
MetaADEDB
Taurine
107-35-7
MetaADEDB
Telithromycin
191114-48-4
ADReCS
Tenofovir
147127-20-6
ADReCS
Tenofovir disoproxil fumarate
202138-50-9
SIDER
Testosterone
58-22-0
ADReCS
Tetracaine
94-24-6
ADReCS
Tetracycline
60-54-8
MetaADEDB
Thalidomide
50-35-1
ADReCS
Thioacetamide
62-55-5
MetaADEDB
Thioguanine
154-42-7
ADReCS
Thiopental
76-75-5
MetaADEDB
Ticlopidine
55142-85-3
ADReCS
Tiron monohydrate
270573-71-2
MetaADEDB
Tizanidine
51322-75-9
ADReCS
Tobramycin
32986-56-4
MetaADEDB
Tocopherols
59-02-9
MetaADEDB
Tranexamic Acid
1197-18-8
ADReCS
Tretinoin
302-79-4
MetaADEDB
Triamcinolone
124-94-7
ADReCS
Trifluridine
70-00-8
MetaADEDB
Trihexyphenidyl
144-11-6
MetaADEDB
Trinitrotoluene
118-96-7
MetaADEDB
Tris-Hcl
1185-53-1
ADReCS
Trovafloxacin
147059-72-1
ADReCS
Ursodeoxycholic acid
128-13-2
MetaADEDB
Valproic Acid
99-66-1
ADReCS
Vecuronium
50700-72-6
MetaADEDB
Venlafaxine
93413-69-5
ADReCS
verapamil
52-53-9
MetaADEDB
Vincristine
57-22-7
ADReCS
Vinorelbine
71486-22-1
ADReCS
Vitamin A
68-26-8
MetaADEDB
Voriconazole
137234-62-9
ADReCS
Warfarin
81-81-2
ADReCS
Xylazine
7361-61-7
MetaADEDB
Zidovudine
30516-87-1
MetaADEDB
Zoledronate
118072-93-8
ADReCS
Zolmitriptan
139264-17-8
ADReCS
List of proteins causing Necrosis
Protein Name
Uniprot ID
Source
Gamma-aminobutyric acid receptor subunit alpha-1 precursor
P14867
22722194
Gamma-aminobutyric acid receptor subunit alpha-6 precursor
P30191
22722194
InAADR: Drug-Protein-ADRs database