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Drugs Causing Mydriasis: 131
Drug Name
CAS Number
Source
Acetaminophen
103-90-2
MetaADEDB
Aldesleukin
85898-30-2
ADReCS
Alprazolam
28981-97-7
ADReCS
Alprostadil
745-65-3
ADReCS
Amantadine
768-94-5
ADReCS
Amitriptyline
50-48-6
ADReCS
Amitriptyline Hydrochloride
549-18-8
MetaADEDB
Amoxapine
14028-44-5
ADReCS
Amphetamine
300-62-9
MetaADEDB
Apraclonidine
66711-21-5
ADReCS
Atomoxetine
83015-26-3
SIDER
Atomoxetine Hydrochloride
82248-59-7
ADReCS
Atropine
51-55-8
ADReCS
Baclofen
1134-47-0
ADReCS
Benzatropine
86-13-5
ADReCS
Bromazepam
1812-30-2
MetaADEDB
Brompheniramine
86-22-6
ADReCS
Bupropion
34841-39-9
ADReCS
Buspirone
36505-84-7
MetaADEDB
Carbachol
51-83-2
MetaADEDB
Carbamazepine
298-46-4
ADReCS
Carbidopa
28860-95-9
ADReCS
Cevimeline
107233-08-9
ADReCS
Chlorpromazine
50-53-3
ADReCS
Citalopram
59729-33-8
ADReCS
Clomipramine
303-49-1
ADReCS
Clonidine
4205-90-7
MetaADEDB
Clozapine
5786-21-0
ADReCS
Cocaine
50-36-2
ADReCS
Cyclizine
82-92-8
MetaADEDB
Cyclobenzaprine
303-53-7
ADReCS
Cyclopentolate
512-15-2
MetaADEDB
Cyproheptadine
129-03-3
MetaADEDB
Desipramine
50-47-5
ADReCS
Desvenlafaxine
93413-62-8
ADReCS
Diazepam
439-14-5
ADReCS
Dicyclomine
77-19-0
ADReCS
diethylpropion
90-84-6
ADReCS
Dipivefrin
52365-63-6
ADReCS
Doxapram
309-29-5
ADReCS
duloxetine
136434-34-9
PROTECT
Ephedrine
299-42-3
MetaADEDB
Escitalopram
128196-01-0
ADReCS
Eszopiclone
138729-47-2
ADReCS
Etorphine
14521-96-1
MetaADEDB
Fludrocortisone
127-31-1
ADReCS
Flunarizine
52468-60-7
MetaADEDB
Fluorometholone
426-13-1
ADReCS
Fluoxetine
54910-89-3
ADReCS
Flurbiprofen
5104-49-4
ADReCS
Fluvoxamine
54739-18-3
ADReCS
Fosphenytoin
93390-81-9
ADReCS
Glatiramer Acetate
147245-92-9
ADReCS
Glycopyrrolate
596-51-0
ADReCS
Hyoscyamine
101-31-5
ADReCS
Ibuprofen
15687-27-1
MetaADEDB
Idazoxan
79944-58-4
MetaADEDB
Imipramine
50-49-7
ADReCS
Iopromide
73334-07-3
ADReCS
Ipratropium bromide
22254-24-6
ADReCS
Lidocaine
137-58-6
MetaADEDB
Lisdexamfetamine
608137-32-2
ADReCS
Maprotiline
10262-69-8
ADReCS
Mecamylamine
60-40-2
ADReCS
Meclofenamic acid
644-62-2
MetaADEDB
Medrysone
2668-66-8
ADReCS
Mefloquine
53230-10-7
MetaADEDB
Mepenzolate
25990-43-6
ADReCS
Metformin
657-24-9
ADReCS
Methadone
76-99-3
ADReCS
Methoxamine
390-28-3
MetaADEDB
Methylphenidate
113-45-1
ADReCS
Methylscopolamine
13265-10-6
ADReCS
Methylscopolamine bromide
155-41-9
ADReCS
Methysergide
361-37-5
ADReCS
Metoclopramide
364-62-5
MetaADEDB
Metolazone
17560-51-9
ADReCS
Montelukast
158966-92-8
ADReCS
Morphine
57-27-2
MetaADEDB
Nabilone
51022-71-0
ADReCS
Naphazoline
835-31-4
ADReCS
Nefazodone
83366-66-9
ADReCS
Nimodipine
66085-59-4
MetaADEDB
Nortriptyline
72-69-5
ADReCS
Olanzapine
132539-06-1
ADReCS
Olopatadine
113806-05-6
PROTECT
Orphenadrine
83-98-7
ADReCS
Oxcarbazepine
28721-07-5
ADReCS
Oxidopamine
1199-18-4
MetaADEDB
Oxybutynin
5633-20-5
ADReCS
Papaverine
58-74-2
MetaADEDB
Paroxetine
61869-08-7
ADReCS
Pegaptanib
222716-86-1
ADReCS
Pegaptanib sodium
CASNA523
SIDER
Perphenazine
58-39-9
ADReCS
Phenobarbital
50-06-6
ADReCS
Phenylephrine
59-42-7
MetaADEDB
Phenytoin
57-41-0
ADReCS
Physostigmine
57-47-6
MetaADEDB
Pilocarpine
92-13-7
MetaADEDB
Prednisolone
50-24-8
ADReCS
Prednisone
53-03-2
MetaADEDB
Pregabalin
148553-50-8
ADReCS
Procaine
59-46-1
MetaADEDB
Prochlorperazine
58-38-8
ADReCS
Procyclidine
77-37-2
ADReCS
Promethazine
60-87-7
ADReCS
Propantheline
298-50-0
ADReCS
Proparacaine
499-67-2
ADReCS
Protriptyline
438-60-8
ADReCS
Quinidine
56-54-2
ADReCS
Quinine
130-95-0
ADReCS
Salbutamol
18559-94-9
ADReCS
scopolamine
51-34-3
ADReCS
Scopolamine Hydrobromide
114-49-8
MetaADEDB
Selegiline
14611-51-9
ADReCS
Sertraline
79617-96-2
ADReCS
Sildenafil
139755-83-2
ADReCS
Sumatriptan
103628-46-2
ADReCS
Technetium Tc 99M Sulfur Colloid
CASNA508
ADReCS
Thiothixene
5591-45-7
ADReCS
Topiramate
97240-79-4
ADReCS
Travoprost
157283-68-6
PROTECT
Trifluoperazine
117-89-5
ADReCS
Trihexyphenidyl
144-11-6
ADReCS
Trimipramine
739-71-9
ADReCS
Tropicamide
1508-75-4
MetaADEDB
Varenicline
249296-44-4
ADReCS
Venlafaxine
93413-69-5
ADReCS
Voriconazole
137234-62-9
ADReCS
Zopiclone
43200-80-2
ADReCS
List of proteins causing Mydriasis
Protein Name
Uniprot ID
Source
5-hydroxytryptamine receptor 2A
P28223
22722194
D(1A) dopamine receptor
P18901
22722194
D(2) dopamine receptor
P14416
22722194
D(4) dopamine receptor
P21917
22722194
Muscarinic acetylcholine receptor M1
P11229
22722194
Muscarinic acetylcholine receptor M2
P08172
22722194
Muscarinic acetylcholine receptor M3
P08483
22722194
Muscarinic acetylcholine receptor M4
P08485
22722194
Muscarinic acetylcholine receptor M5
P08912
22722194
Sodium-dependent dopamine transporter
Q01959
22722194
InAADR: Drug-Protein-ADRs database