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Drugs Causing Methaemoglobinaemia: 60
Drug Name
CAS Number
Source
Acebutolol
37517-30-9
MetaADEDB
Acetyl Sulfisoxazole
80-74-0
ADReCS
Aciclovir
59277-89-3
MetaADEDB
Amitriptyline Hydrochloride
549-18-8
MetaADEDB
Amyl Nitrite
463-04-7
ADReCS
Atovaquone
95233-18-4
ADReCS
Bacitracin
1405-87-4
MetaADEDB
Benzocaine
94-09-7
ADReCS
Cefdinir
91832-40-5
MetaADEDB
Cefotaxime
63527-52-6
MetaADEDB
Cephalexin
15686-71-2
MetaADEDB
Chlorzoxazone
95-25-0
MetaADEDB
Ciprofloxacin
85721-33-1
ADReCS
Cisplatin
15663-27-1
MetaADEDB
Clindamycin
18323-44-9
MetaADEDB
Clotrimazole
23593-75-1
MetaADEDB
Codeine
76-57-3
MetaADEDB
Cyclophosphamide
50-18-0
ADReCS
Dapsone
80-08-0
ADReCS
docusate
577-11-7
MetaADEDB
Enalapril
75847-73-3
MetaADEDB
Flutamide
13311-84-7
ADReCS
Ifosfamide
3778-73-2
ADReCS
iloprost
78919-13-8
ADReCS
Isoamyl Nitrite
110-46-3
SIDER
Isosorbide
652-67-5
ADReCS
Isosorbide Dinitrate
87-33-2
ADReCS
Isosorbide Mononitrate
16051-77-7
MetaADEDB
Lenalidomide
191732-72-6
MetaADEDB
Lidocaine
137-58-6
ADReCS
Memantine
19982-08-2
MetaADEDB
METHYLENE BLUE
61-73-4
MetaADEDB
Metoclopramide
364-62-5
ADReCS
Micafungin
235114-32-6
MetaADEDB
Nitric Oxide
10102-43-9
PROTECT
Nitrofurantoin
67-20-9
ADReCS
Nitroglycerin
55-63-0
ADReCS
Nitroprusside
15078-28-1
ADReCS
Nortriptyline
72-69-5
MetaADEDB
Pantoprazole
102625-70-7
MetaADEDB
Phenazopyridine
94-78-0
ADReCS
Phenylazopyridine hydrochloride
CASNA521
SIDER
Primaquine
90-34-6
ADReCS
Propofol
2078-54-8
MetaADEDB
Rasburicase
134774-45-1
PROTECT
Riluzole
1744-22-5
ADReCS
Sevelamer
152751-57-0
MetaADEDB
Silver sulfadiazine
22199-08-2
MetaADEDB
Sodium bicarbonate
144-55-8
MetaADEDB
Sulfadiazine
68-35-9
ADReCS
Sulfasalazine
599-79-1
ADReCS
Sulfisoxazole
127-69-5
ADReCS
Sumatriptan
103628-46-2
MetaADEDB
Temozolomide
85622-93-1
MetaADEDB
Tenofovir
147127-20-6
MetaADEDB
Trazodone
19794-93-5
ADReCS
Tretinoin
302-79-4
MetaADEDB
Trimethadione
127-48-0
ADReCS
Trimethoprim
738-70-5
ADReCS
Ursodeoxycholic acid
128-13-2
MetaADEDB
List of proteins causing Methaemoglobinaemia
Protein Name
Uniprot ID
Source
Amiloride-sensitive Sodium channel subunit Alpha
P37088
22722194
Amiloride-sensitive Sodium channel subunit Beta
P51168
22722194
Amiloride-sensitive Sodium channel subunit delta
P51172
22722194
Amiloride-sensitive Sodium channel subunit gamma
P51170
22722194
Sodium channel protein type 1 subunit alpha
P35498
22722194
Sodium channel protein type 10 subunit alpha
Q9Y5Y9
22722194
Sodium channel protein type 11 subunit alpha
Q9UI33
22722194
Sodium channel protein type 2 subunit alpha
Q99250
22722194
Sodium channel protein type 3 subunit alpha
Q9NY46
22722194
Sodium channel protein type 4 subunit alpha
P35499
22722194
Sodium channel protein type 5 subunit alpha
Q14524
22722194
Sodium channel protein type 7 subunit alpha
Q01118
22722194
Sodium channel protein type 8 subunit alpha
Q9UQD0
22722194
Sodium channel protein type 9 subunit alpha
Q15858
22722194
Sodium channel subunit beta-1 precursor
Q07699
22722194
Sodium channel subunit beta-2 precursor
O60939
22722194
Sodium channel subunit beta-3 precursor
Q9NY72
22722194
Sodium channel subunit beta-4 precursor
Q8IWT1
22722194
InAADR: Drug-Protein-ADRs database