Drugs Causing Hypertonia: 430
Drug Name	CAS Number	Source
Abciximab	143653-53-6	ADReCS
Acarbose	56180-94-0	MetaADEDB
Acebutolol	37517-30-9	MetaADEDB
Acitretin	55079-83-9	ADReCS
Adapalene	106685-40-9	MetaADEDB
Adenosine	58-61-7	MetaADEDB
Alfuzosin	81403-80-7	MetaADEDB
Almotriptan	154323-57-6	SIDER
Almotriptan Malate	181183-52-8	ADReCS
Alprazolam	28981-97-7	MetaADEDB
Alvimopan	156053-89-3	MetaADEDB
Amantadine	768-94-5	ADReCS
Amitriptyline Hydrochloride	549-18-8	MetaADEDB
Amlodipine	88150-42-9	ADReCS
Amoxapine	14028-44-5	MetaADEDB
Amphotericin B	1397-89-3	ADReCS
Ampicillin	69-53-4	MetaADEDB
Anastrozole	120511-73-1	ADReCS
Apomorphine hydrochloride hemihydrate	41372-20-7	MetaADEDB
Aripiprazole	129722-12-9	ADReCS
Atorvastatin	134523-00-5	ADReCS
Atracurium	64228-79-1	MetaADEDB
Atropine	51-55-8	ADReCS
Azathioprine	446-86-6	MetaADEDB
Azelaic Acid	123-99-9	MetaADEDB
Azelastine	58581-89-8	MetaADEDB
Azithromycin	83905-01-5	MetaADEDB
Bacitracin	1405-87-4	MetaADEDB
Baclofen	1134-47-0	ADReCS
Benazepril	86541-75-5	ADReCS
Benzatropine	86-13-5	MetaADEDB
Benzylpenicillin	61-33-6	MetaADEDB
Betaxolol	63659-18-7	ADReCS
Bethanechol	674-38-4	MetaADEDB
Bexarotene	153559-49-0	PROTECT
Bicalutamide	90357-06-5	ADReCS
Biperiden	514-65-8	MetaADEDB
Bisacodyl	603-50-9	MetaADEDB
Bleomycin	11056-06-7	MetaADEDB
Botulinum Toxin Type A	93384-43-1	ADReCS
Brinzolamide	138890-62-7	ADReCS
Bromocriptine	25614-03-3	MetaADEDB
Budesonide	51333-22-3	ADReCS
Bumetanide	28395-03-1	MetaADEDB
Bupropion	34841-39-9	ADReCS
Caffeine	58-08-2	MetaADEDB
Calcipotriol	112965-21-6	MetaADEDB
Calcitriol	32222-06-3	MetaADEDB
Calcium	7440-70-2	MetaADEDB
Candesartan	139481-59-7	ADReCS
Captopril	62571-86-2	MetaADEDB
Carbamazepine	298-46-4	ADReCS
Carbimazole	22232-54-8	MetaADEDB
Carisoprodol	78-44-4	MetaADEDB
Carvedilol	72956-09-3	MetaADEDB
Cefaclor	53994-73-3	ADReCS
Cefadroxil	66592-87-8	MetaADEDB
Cefazolin	25953-19-9	ADReCS
Cefditoren	104145-95-1	ADReCS
Ceftriaxone	73384-59-5	ADReCS
Cefuroxime axetil	64544-07-6	MetaADEDB
Celecoxib	169590-42-5	ADReCS
Cephalexin	15686-71-2	MetaADEDB
Cerivastatin	145599-86-6	ADReCS
Cetirizine	83881-51-0	ADReCS
Cevimeline	107233-08-9	ADReCS
Chloramphenicol	56-75-7	MetaADEDB
Chlordiazepoxide	58-25-3	MetaADEDB
Chlorhexidine	55-56-1	MetaADEDB
Chlorhexidine gluconate	18472-51-0	MetaADEDB
Chlorpromazine	50-53-3	MetaADEDB
Chlorpropamide	94-20-2	MetaADEDB
Chorionic Gonadotropin	9002-61-3	ADReCS
Ciclesonide	141845-82-1	MetaADEDB
Cidofovir	113852-37-2	ADReCS
Cilest	79871-54-8	MetaADEDB
Cimetidine	51481-61-9	MetaADEDB
Cinacalcet	226256-56-0	MetaADEDB
Ciprofloxacin	85721-33-1	ADReCS
Citalopram	59729-33-8	ADReCS
Clindamycin	18323-44-9	MetaADEDB
clindamycin phosphate	24729-96-2	MetaADEDB
Clobazam	22316-47-8	MetaADEDB
Clobetasol propionate	25122-46-7	MetaADEDB
Clomipramine	303-49-1	ADReCS
Clonazepam	1622-61-3	ADReCS
Clonidine	4205-90-7	MetaADEDB
Clotrimazole	23593-75-1	MetaADEDB
coenzyme Q10	303-98-0	MetaADEDB
Colchicine	64-86-8	MetaADEDB
Conjugated Estrogens	438-67-5	ADReCS
Cortisone	53-06-5	MetaADEDB
Cortisone acetate	50-04-4	MetaADEDB
Cyclobenzaprine	303-53-7	ADReCS
Cyproheptadine	129-03-3	MetaADEDB
Dantrolene	7261-97-4	MetaADEDB
Dapsone	80-08-0	MetaADEDB
Darifenacin	133099-04-4	MetaADEDB
Daunorubicin	20830-81-3	ADReCS
deflazacort	14484-47-0	MetaADEDB
Dehydroepiandrosterone	53-43-0	MetaADEDB
Delavirdine	136817-59-9	ADReCS
Desloratadine	100643-71-8	MetaADEDB
Diazepam	439-14-5	MetaADEDB
diazinon	333-41-5	MetaADEDB
Diclofenac	15307-86-5	ADReCS
Dicloxacillin	3116-76-5	MetaADEDB
Dicyclomine	77-19-0	MetaADEDB
Diflunisal	22494-42-4	MetaADEDB
Diltiazem	42399-41-7	ADReCS
Dimenhydrinate	523-87-5	MetaADEDB
dimethylpolysiloxane	9016-00-6	MetaADEDB
Dinoprostone	363-24-6	ADReCS
diosmin	520-27-4	MetaADEDB
Dipyridamole	58-32-2	ADReCS
Divalproex Sodium	76584-70-8	ADReCS
docusate	577-11-7	MetaADEDB
Dofetilide	115256-11-6	MetaADEDB
Dolasetron	115956-12-2	MetaADEDB
Donepezil	120014-06-4	ADReCS
Doxazosin	74191-85-8	ADReCS
Doxepin	1668-19-5	MetaADEDB
Doxercalciferol	54573-75-0	ADReCS
Doxorubicin	23214-92-8	ADReCS
Doxycycline	564-25-0	MetaADEDB
duloxetine	136434-34-9	MetaADEDB
Econazole	27220-47-9	MetaADEDB
Eflornithine Hydrochloride	62878-23-9	ADReCS
Eletriptan	143322-58-1	ADReCS
Enoxaparin	9005-49-6	MetaADEDB
Entacapone	130929-57-6	MetaADEDB
Ephedrine	299-42-3	MetaADEDB
Esomeprazole	119141-88-7	ADReCS
Estradiol	50-28-2	ADReCS
Estramustine	2998-57-4	MetaADEDB
Estrogens Conjugated Synthetic A	12126-59-9	ADReCS
Eszopiclone	138729-47-2	ADReCS
Everolimus	159351-69-6	MetaADEDB
Exemestane	107868-30-4	MetaADEDB
Ezetimibe	163222-33-1	MetaADEDB
Fenofibrate	49562-28-9	ADReCS
Fenoterol	13392-18-2	MetaADEDB
Fentanyl	437-38-7	ADReCS
Fexofenadine	83799-24-0	MetaADEDB
Finasteride	98319-26-7	MetaADEDB
Fioricet	122018-95-5	MetaADEDB
Fludrocortisone	127-31-1	ADReCS
Flunitrazepam	1622-62-4	MetaADEDB
Fluoxetine	54910-89-3	ADReCS
Fluphenazine decanoate	5002-47-1	MetaADEDB
Flurazepam	17617-23-1	MetaADEDB
Flurbiprofen	5104-49-4	ADReCS
Fluticasone Propionate	80474-14-2	MetaADEDB
Fluvoxamine	54739-18-3	ADReCS
Formoterol	73573-87-2	MetaADEDB
Fosinopril	98048-97-6	MetaADEDB
Frovatriptan	158747-02-5	ADReCS
Fulvestrant	129453-61-8	MetaADEDB
Gabapentin	60142-96-3	ADReCS
Gadobenate Dimeglumine	113662-23-0	ADReCS
gadolinium	7440-54-2	MetaADEDB
Gadoversetamide	131069-91-5	ADReCS
Galantamine	357-70-0	ADReCS
Gamma-Hydroxybutyrate	591-81-1	ADReCS
Ganciclovir	82410-32-0	ADReCS
Gatifloxacin	112811-59-3	ADReCS
Gemfibrozil	25812-30-0	MetaADEDB
Glatiramer Acetate	147245-92-9	ADReCS
Glimepiride	93479-97-1	MetaADEDB
Glipizide	29094-61-9	ADReCS
Glutamine	56-85-9	MetaADEDB
gold	7440-57-5	MetaADEDB
Goserelin	65807-02-5	ADReCS
haloperidol decanoate	74050-97-8	MetaADEDB
human insulin	11061-68-0	ADReCS
Hydralazine	86-54-4	MetaADEDB
Hydrochlorothiazide	58-93-5	MetaADEDB
hydrocodone	125-29-1	MetaADEDB
Hydromorphone	466-99-9	ADReCS
hydroxyzine pamoate	10246-75-0	MetaADEDB
Ibandronate	114084-78-5	PROTECT
Ibritumomab	174722-31-7	PROTECT
Ibuprofen	15687-27-1	ADReCS
Imatinib	152459-95-5	MetaADEDB
Imipramine	50-49-7	MetaADEDB
Indapamide	26807-65-8	ADReCS
Indomethacin	53-86-1	MetaADEDB
Interferon Alfa-2a Recombinant	76543-88-9	ADReCS
Interferon beta-1a	145258-61-3	ADReCS
Interferon beta-1b	145155-23-3	ADReCS
Iodine	7553-56-2	ADReCS
Iohexol	66108-95-0	ADReCS
Iopamidol	60166-93-0	ADReCS
Iopromide	73334-07-3	ADReCS
Isoflurane	26675-46-7	MetaADEDB
Isosorbide Mononitrate	16051-77-7	MetaADEDB
Ketoconazole	65277-42-1	MetaADEDB
Ketorolac	66635-83-4	MetaADEDB
ketorolac tromethamine	74103-07-4	MetaADEDB
L-Carnitine	541-15-1	ADReCS
Labetalol	36894-69-6	MetaADEDB
Lamotrigine	84057-84-1	ADReCS
Lansoprazole	103577-45-3	ADReCS
Lenalidomide	191732-72-6	MetaADEDB
Letrozole	112809-51-5	MetaADEDB
Leuprolide acetate	74381-53-6	MetaADEDB
Levocabastine	79516-68-0	MetaADEDB
Levodopa	59-92-7	MetaADEDB
Levofloxacin	100986-85-4	ADReCS
Levomepromazine	60-99-1	MetaADEDB
Levonorgestrel	797-63-7	MetaADEDB
Lisinopril	83915-83-7	MetaADEDB
Lithium	7439-93-2	ADReCS
Lomefloxacin	98079-51-7	ADReCS
Lomotil	55840-97-6	MetaADEDB
Lopinavir	192725-17-0	MetaADEDB
Loratadine	79794-75-5	MetaADEDB
Lorazepam	846-49-1	MetaADEDB
Losartan	114798-26-4	MetaADEDB
Loteprednol	82034-46-6	MetaADEDB
Lovastatin	75330-75-5	MetaADEDB
Lubiprostone	136790-76-6	MetaADEDB
Lutein	127-40-2	MetaADEDB
Magnesium	7439-95-4	MetaADEDB
magnesium citrate	7779-25-1	MetaADEDB
magnesium hydroxide	1309-42-8	MetaADEDB
Mefloquine	53230-10-7	MetaADEDB
melatonin	73-31-4	MetaADEDB
Meloxicam	71125-38-7	MetaADEDB
Memantine	19982-08-2	ADReCS
Meprobamate	57-53-4	MetaADEDB
Mesalazine	89-57-6	ADReCS
Metaxalone	1665-48-1	MetaADEDB
Methocarbamol	532-03-6	MetaADEDB
Methylphenidate	113-45-1	MetaADEDB
Methylprednisolone	83-43-2	MetaADEDB
methylprednisolone acetate	53-36-1	MetaADEDB
Methyltestosterone	58-18-4	MetaADEDB
Metolazone	17560-51-9	ADReCS
Metoprolol	37350-58-6	MetaADEDB
Midodrine	133163-28-7	MetaADEDB
Minocycline	10118-90-8	MetaADEDB
Mirtazapine	61337-67-5	ADReCS
Misoprostol	59122-46-2	MetaADEDB
moclobemide	71320-77-9	MetaADEDB
Modafinil	68693-11-8	ADReCS
Mometasone	105102-22-5	MetaADEDB
Montelukast	158966-92-8	MetaADEDB
Morphine	57-27-2	ADReCS
Moxifloxacin	151096-09-2	ADReCS
Mycophenolate mofetil	128794-94-5	ADReCS
Mycophenolic acid	24280-93-1	ADReCS
Nabumetone	42924-53-8	MetaADEDB
Nadolol	42200-33-9	MetaADEDB
Nalbuphine	20594-83-6	MetaADEDB
Naloxone	465-65-6	MetaADEDB
Nandrolone decanoate	360-70-3	MetaADEDB
Naproxen	22204-53-1	ADReCS
Naratriptan	121679-13-8	MetaADEDB
Nefazodone	83366-66-9	ADReCS
Nelarabine	121032-29-9	ADReCS
Nelfinavir	159989-64-7	MetaADEDB
Neostigmine	59-99-4	MetaADEDB
Nepafenac	78281-72-8	MetaADEDB
Niacin	59-67-6	ADReCS
Nicardipine	55985-32-5	ADReCS
Nifedipine	21829-25-4	ADReCS
Nisoldipine	63675-72-9	ADReCS
Nitrofurantoin	67-20-9	MetaADEDB
Nitroglycerin	55-63-0	MetaADEDB
Nizatidine	76963-41-2	MetaADEDB
Norfloxacin	70458-96-7	MetaADEDB
Nortriptyline	72-69-5	MetaADEDB
Nystatin	1400-61-9	MetaADEDB
Octreotide	83150-76-9	MetaADEDB
Ofloxacin	82419-36-1	ADReCS
Olanzapine	132539-06-1	ADReCS
Olopatadine	113806-05-6	MetaADEDB
Omeprazole	73590-58-6	ADReCS
Orlistat	96829-58-2	MetaADEDB
Orphenadrine	83-98-7	MetaADEDB
Oxaprozin	21256-18-8	MetaADEDB
Oxcarbazepine	28721-07-5	ADReCS
Oxybutynin	5633-20-5	ADReCS
Oxycodone	76-42-6	ADReCS
Oxytocin	50-56-6	ADReCS
Paliperidone	144598-75-4	ADReCS
Pamidronate	40391-99-9	MetaADEDB
Pantoprazole	102625-70-7	ADReCS
Paroxetine	61869-08-7	ADReCS
Penicillin v	87-08-1	MetaADEDB
Perflutren	76-19-7	ADReCS
Pergolide	66104-22-1	ADReCS
Perindopril	107133-36-8	ADReCS
Perphenazine	58-39-9	MetaADEDB
Pethidine	57-42-1	MetaADEDB
Phenacetin	62-44-2	MetaADEDB
Phenelzine	51-71-8	ADReCS
Pheniramine	86-21-5	MetaADEDB
Phenolphthalein	77-09-8	MetaADEDB
Phosphorus	7723-14-0	MetaADEDB
Pioglitazone	111025-46-8	MetaADEDB
Piracetam	7491-74-9	MetaADEDB
Pirbuterol	38677-81-5	MetaADEDB
Polyethylene Glycol	25322-68-3	MetaADEDB
Potassium Acetate	127-08-2	MetaADEDB
Pramipexole	104632-26-0	ADReCS
Pranoprofen	52549-17-4	MetaADEDB
Prazepam	2955-38-6	MetaADEDB
Prazosin	19216-56-9	MetaADEDB
Pregabalin	148553-50-8	ADReCS
Primidone	125-33-7	MetaADEDB
Prochlorperazine edisylate	1257-78-9	MetaADEDB
Procyclidine	77-37-2	MetaADEDB
Progesterone	57-83-0	ADReCS
Promazine	58-40-2	MetaADEDB
Promethazine	60-87-7	ADReCS
Propafenone	54063-53-5	ADReCS
Propiomazine	362-29-8	MetaADEDB
Propofol	2078-54-8	ADReCS
Propranolol	525-66-6	MetaADEDB
Pyridostigmine	155-97-5	ADReCS
Quetiapine	111974-69-7	ADReCS
Quinapril	85441-61-8	MetaADEDB
Quinidine	56-54-2	MetaADEDB
Rabeprazole	117976-89-3	ADReCS
Raltitrexed	112887-68-0	ADReCS
Rasagiline	136236-51-6	ADReCS
reboxetine	98769-81-4	MetaADEDB
Reslin	39471-19-7	MetaADEDB
Ribavirin	36791-04-5	PROTECT
Rifapentine	61379-65-5	ADReCS
Rifaximin	80621-81-4	MetaADEDB
Riluzole	1744-22-5	ADReCS
Risedronate	105462-24-6	ADReCS
Risperidone	106266-06-2	ADReCS
Rivastigmine	123441-03-2	ADReCS
Rizatriptan	145202-66-0	MetaADEDB
Ropinirole	91374-21-9	ADReCS
Rosuvastatin	287714-41-4	ADReCS
rosuvastatin calcium	147098-20-2	MetaADEDB
Rotigotine	99755-59-6	ADReCS
Salbutamol	18559-94-9	ADReCS
Salmeterol	89365-50-4	MetaADEDB
Saxagliptin	361442-04-8	MetaADEDB
scopolamine	51-34-3	MetaADEDB
Selegiline	14611-51-9	ADReCS
Sertraline	79617-96-2	ADReCS
Sevelamer	152751-57-0	MetaADEDB
Sevoflurane	28523-86-6	ADReCS
Sibutramine	106650-56-0	ADReCS
Sildenafil	139755-83-2	ADReCS
Silver sulfadiazine	22199-08-2	MetaADEDB
simethicone	8050-81-5	MetaADEDB
Sirolimus	53123-88-9	ADReCS
Sodium Ferric Gluconate Complex	34089-81-1	ADReCS
Solifenacin	242478-37-1	MetaADEDB
Somatropin recombinant	12629-01-5	PROTECT
Streptomycin	57-92-1	MetaADEDB
Succinylcholine	306-40-1	MetaADEDB
sulfamethoxazole	723-46-6	MetaADEDB
sulpiride	15676-16-1	MetaADEDB
Tacrine	321-64-2	ADReCS
Tacrolimus	104987-11-3	ADReCS
Tadalafil	171596-29-5	MetaADEDB
Tamsulosin	106133-20-4	ADReCS
Technetium Tc 99M Sulfur Colloid	CASNA508	ADReCS
Telmisartan	144701-48-4	ADReCS
Temazepam	846-50-4	MetaADEDB
Terazosin	63590-64-7	MetaADEDB
Terbinafine	91161-71-6	ADReCS
Terbutaline	23031-25-6	ADReCS
Terconazole	67915-31-5	MetaADEDB
Testosterone cypionate	58-20-8	MetaADEDB
Testosterone enanthate	315-37-7	MetaADEDB
Tetrabenazine	58-46-8	ADReCS
Tetracycline	60-54-8	MetaADEDB
Tetrahydrobiopterin	17528-72-2	MetaADEDB
Thalidomide	50-35-1	ADReCS
Theophylline	58-55-9	MetaADEDB
Thiopental	76-75-5	MetaADEDB
Thiotepa	52-24-4	MetaADEDB
Thyrotropin Releasing Hormone	24305-27-9	ADReCS
Tiagabine	115103-54-3	ADReCS
Tilidine	51931-66-9	MetaADEDB
Tioconazole	65899-73-2	MetaADEDB
Tiotropium	186691-13-4	MetaADEDB
Tizanidine	51322-75-9	MetaADEDB
Tobramycin	32986-56-4	MetaADEDB
Tolazamide	1156-19-0	ADReCS
Tolcapone	134308-13-7	ADReCS
Tolterodine	124937-51-5	MetaADEDB
Topiramate	97240-79-4	ADReCS
Tramadol	27203-92-5	ADReCS
Tranylcypromine	155-09-9	MetaADEDB
Trastuzumab	180288-69-1	PROTECT
Tretinoin	302-79-4	MetaADEDB
Triamcinolone	124-94-7	MetaADEDB
Triamcinolone acetonide	76-25-5	MetaADEDB
Triamterene	396-01-0	MetaADEDB
Trifluoperazine	117-89-5	MetaADEDB
Trimethobenzamide	138-56-7	MetaADEDB
Trimethoprim	738-70-5	ADReCS
Trimipramine	739-71-9	MetaADEDB
Tropisetron	89565-68-4	MetaADEDB
Trovafloxacin	147059-72-1	ADReCS
valacyclovir	124832-27-5	MetaADEDB
Valdecoxib	181695-72-7	ADReCS
valganciclovir	175865-60-8	SIDER
Valproic Acid	99-66-1	ADReCS
Vardenafil	224785-90-4	ADReCS
Varenicline	249296-44-4	ADReCS
Venlafaxine	93413-69-5	ADReCS
Vigabatrin	60643-86-9	ADReCS
Vinblastine	865-21-4	MetaADEDB
Vinorelbine	71486-22-1	MetaADEDB
Vitamin A	68-26-8	MetaADEDB
Voriconazole	137234-62-9	ADReCS
Warfarin	81-81-2	MetaADEDB
Zalcitabine	7481-89-2	ADReCS
Zaleplon	151319-34-5	ADReCS
Ziconotide	107452-89-1	ADReCS
Zidovudine	30516-87-1	MetaADEDB
Zileuton	111406-87-2	ADReCS
zinc	7440-66-6	MetaADEDB
Ziprasidone	146939-27-7	ADReCS
Zoledronate	118072-93-8	MetaADEDB
Zolmitriptan	139264-17-8	ADReCS
Zonisamide	68291-97-4	ADReCS
Zopiclone	43200-80-2	ADReCS

List of proteins causing Hypertonia
Protein Name	Uniprot ID	Source