Drugs Causing Hepatic Necrosis: 189
Drug Name	CAS Number	Source
Abacavir	136470-78-5	MetaADEDB
Acetaminophen	103-90-2	MetaADEDB
Acetazolamide	59-66-5	ADReCS
Acetyl Sulfisoxazole	80-74-0	ADReCS
Acetylcysteine	616-91-1	MetaADEDB
Aciclovir	59277-89-3	MetaADEDB
Acitretin	55079-83-9	MetaADEDB
Albendazole	54965-21-8	MetaADEDB
Allopurinol	315-30-0	ADReCS
Aminophylline	317-34-0	MetaADEDB
Amoxicillin	26787-78-0	MetaADEDB
Ampicillin	69-53-4	MetaADEDB
Anidulafungin	166663-25-8	ADReCS
Atomoxetine Hydrochloride	82248-59-7	MetaADEDB
Atracurium	64228-79-1	MetaADEDB
Azathioprine	446-86-6	MetaADEDB
Azelaic Acid	123-99-9	MetaADEDB
Azithromycin	83905-01-5	ADReCS
Baclofen	1134-47-0	MetaADEDB
Balsalazide	80573-04-2	ADReCS
benidipine	105979-17-7	MetaADEDB
Benzoyl Peroxide	94-36-0	MetaADEDB
Benzylpenicillin	61-33-6	MetaADEDB
Bisacodyl	603-50-9	MetaADEDB
Bortezomib	179324-69-7	MetaADEDB
Bosentan	147536-97-8	MetaADEDB
Budesonide	51333-22-3	MetaADEDB
Bumetanide	28395-03-1	MetaADEDB
Bupivacaine	2180-92-9	MetaADEDB
Busulfan	55-98-1	ADReCS
Butalbital	77-26-9	MetaADEDB
Caffeine	58-08-2	MetaADEDB
Calcipotriol	112965-21-6	MetaADEDB
Caspofungin	179463-17-3	ADReCS
Cefixime	79350-37-1	MetaADEDB
Cefotaxime	63527-52-6	MetaADEDB
Cefuroxime	55268-75-2	MetaADEDB
Cerivastatin	145599-86-6	ADReCS
Chlordiazepoxide	58-25-3	MetaADEDB
Chlorothiazide	58-94-6	MetaADEDB
Chlorphenamine	132-22-9	MetaADEDB
Cidofovir	113852-37-2	ADReCS
Ciprofloxacin	85721-33-1	ADReCS
Citalopram	59729-33-8	ADReCS
cloxacillin	61-72-3	MetaADEDB
Clozapine	5786-21-0	MetaADEDB
Codeine	76-57-3	MetaADEDB
Colestipol	26658-42-4	MetaADEDB
cyamemazine	3546-03-0	MetaADEDB
Cyproterone	2098-66-0	ADReCS
Desflurane	57041-67-5	ADReCS
Diclofenac	15307-86-5	ADReCS
Didanosine	69655-05-6	MetaADEDB
Digoxin	20830-75-5	MetaADEDB
dihydrocodeine	125-28-0	MetaADEDB
Dobutamine	34368-04-2	MetaADEDB
dothiepin	113-53-1	MetaADEDB
Doxycycline	564-25-0	MetaADEDB
Efavirenz	154598-52-4	MetaADEDB
Enflurane	13838-16-9	ADReCS
Eptifibatide	188627-80-7	MetaADEDB
Erythromycin	114-07-8	MetaADEDB
Escitalopram	128196-01-0	ADReCS
Etodolac	41340-25-4	ADReCS
Ezetimibe	163222-33-1	MetaADEDB
Fentanyl	437-38-7	MetaADEDB
Floxuridine	50-91-9	ADReCS
Fluconazole	86386-73-4	ADReCS
Flucytosine	2022-85-7	ADReCS
Fluoride Ion	16984-48-8	ADReCS
Flupenthixol	2709-56-0	MetaADEDB
Flutamide	13311-84-7	ADReCS
Fluvastatin	93957-54-1	ADReCS
Fosfomycin	23155-02-4	ADReCS
Fosphenytoin	93390-81-9	MetaADEDB
gabexate mesilate	56974-61-9	MetaADEDB
Ganciclovir	82410-32-0	MetaADEDB
Glatiramer Acetate	147245-92-9	MetaADEDB
Halothane	151-67-7	ADReCS
heroin	561-27-3	MetaADEDB
Hydromorphone	466-99-9	MetaADEDB
Ibuprofen	15687-27-1	ADReCS
Idarubicin	58957-92-9	MetaADEDB
Ifosfamide	3778-73-2	MetaADEDB
Imatinib	152459-95-5	ADReCS
Isoflurane	26675-46-7	ADReCS
Isoniazid	54-85-3	MetaADEDB
Ketamine	6740-88-1	MetaADEDB
Ketoconazole	65277-42-1	MetaADEDB
Labetalol	36894-69-6	ADReCS
Lamotrigine	84057-84-1	MetaADEDB
Leflunomide	75706-12-6	ADReCS
Levobunolol	47141-42-4	MetaADEDB
Levonorgestrel	797-63-7	ADReCS
Lithium	7439-93-2	MetaADEDB
Lomefloxacin	98079-51-7	ADReCS
Lorazepam	846-49-1	MetaADEDB
Lovastatin	75330-75-5	ADReCS
Maprotiline	10262-69-8	MetaADEDB
Meprobamate	57-53-4	MetaADEDB
Mercaptopurine	50-44-2	PROTECT
Mesalazine	89-57-6	ADReCS
Mesna	19767-45-4	ADReCS
Methadone	76-99-3	MetaADEDB
Methazolamide	554-57-4	ADReCS
Methocarbamol	532-03-6	MetaADEDB
Methyldopa	555-30-6	MetaADEDB
Metronidazole	443-48-1	MetaADEDB
Mexiletine	31828-71-4	ADReCS
Moxifloxacin	151096-09-2	ADReCS
moxonidine	75438-57-2	MetaADEDB
Naproxen	22204-53-1	MetaADEDB
Nebivolol	99200-09-6	MetaADEDB
Nefazodone	83366-66-9	ADReCS
Nelfinavir	159989-64-7	MetaADEDB
Neostigmine	59-99-4	MetaADEDB
Nevirapine	129618-40-2	ADReCS
Nicardipine	55985-32-5	MetaADEDB
Nilvadipine	75530-68-6	MetaADEDB
Nitrofurantoin	67-20-9	ADReCS
Norfloxacin	70458-96-7	ADReCS
Nortriptyline	72-69-5	ADReCS
Nystatin	1400-61-9	MetaADEDB
Ofloxacin	82419-36-1	ADReCS
olmesartan medoxomil	144689-63-4	MetaADEDB
Olsalazine	15722-48-2	ADReCS
Omeprazole	73590-58-6	ADReCS
Ondansetron	99614-02-5	ADReCS
Orphenadrine	83-98-7	MetaADEDB
Oxandrolone	53-39-4	ADReCS
Oxybutynin	5633-20-5	MetaADEDB
Oxymetholone	434-07-1	ADReCS
Oxymorphone	76-41-5	MetaADEDB
Paclitaxel	33069-62-4	ADReCS
Pancuronium	15500-66-0	MetaADEDB
Pantoprazole	102625-70-7	MetaADEDB
Paroxetine	61869-08-7	ADReCS
Penicillamine	52-67-5	MetaADEDB
Penicillin v	87-08-1	MetaADEDB
Pentazocine	359-83-1	MetaADEDB
Pergolide	66104-22-1	MetaADEDB
Phenelzine	51-71-8	ADReCS
Phenprocoumon	435-97-2	MetaADEDB
Pravastatin	81093-37-0	ADReCS
Prazosin	19216-56-9	MetaADEDB
Primidone	125-33-7	MetaADEDB
Probenecid	57-66-9	ADReCS
Progesterone	57-83-0	ADReCS
Propofol	2078-54-8	MetaADEDB
Propylthiouracil	51-52-5	MetaADEDB
Ramipril	87333-19-5	ADReCS
Rifaximin	80621-81-4	MetaADEDB
rilmenidine	54187-04-1	MetaADEDB
Ritonavir	155213-67-5	MetaADEDB
Rosiglitazone	122320-73-4	MetaADEDB
Sevoflurane	28523-86-6	ADReCS
Silver sulfadiazine	22199-08-2	ADReCS
Simvastatin	79902-63-9	ADReCS
Sirolimus	53123-88-9	ADReCS
Streptomycin	57-92-1	MetaADEDB
strontium ranelate	135459-87-9	MetaADEDB
Sulfacetamide	144-80-9	ADReCS
sulfamethoxazole	723-46-6	MetaADEDB
Sulfasalazine	599-79-1	ADReCS
Sulfisoxazole	127-69-5	ADReCS
Tacrolimus	104987-11-3	ADReCS
Tadalafil	171596-29-5	MetaADEDB
Telithromycin	191114-48-4	ADReCS
Tenofovir	147127-20-6	MetaADEDB
Terbutaline	23031-25-6	MetaADEDB
Thiamine	59-43-8	MetaADEDB
Thioguanine	154-42-7	ADReCS
Thiopental	76-75-5	MetaADEDB
Ticlopidine	55142-85-3	ADReCS
Tizanidine	51322-75-9	ADReCS
Tolcapone	134308-13-7	MetaADEDB
Tranilast	53902-12-8	MetaADEDB
Trimipramine	739-71-9	MetaADEDB
Tris-Hcl	1185-53-1	ADReCS
Tromethamine	77-86-1	ADReCS
Trovafloxacin	147059-72-1	ADReCS
Troxipide	30751-05-4	MetaADEDB
Truvada	731772-45-5	MetaADEDB
valpromide	2430-27-5	MetaADEDB
Vasopressin	11000-17-2	MetaADEDB
Venlafaxine	93413-69-5	ADReCS
xylometazoline	526-36-3	MetaADEDB
Zidovudine	30516-87-1	MetaADEDB
Zolmitriptan	139264-17-8	MetaADEDB

List of proteins causing Hepatic Necrosis
Protein Name	Uniprot ID	Source