Drugs Causing Gastrointestinal Perforation: 109
Drug Name	CAS Number	Source
Acarbose	56180-94-0	MetaADEDB
Aflibercept	862111-32-8	PROTECT
Alendronate	66376-36-1	ADReCS
Alizapride	59338-93-1	MetaADEDB
Alosetron	122852-42-0	ADReCS
Alvimopan	156053-89-3	MetaADEDB
Ambroxol	18683-91-5	MetaADEDB
Amezinium	41658-78-0	MetaADEDB
Aminophylline	317-34-0	MetaADEDB
Ampicillin	69-53-4	MetaADEDB
Aprepitant	170729-80-3	MetaADEDB
Axitinib	319460-85-0	PROTECT
Azasetron	123040-69-7	MetaADEDB
Azithromycin	83905-01-5	MetaADEDB
benzbromarone	3562-84-3	MetaADEDB
beraprost sodium	88475-69-8	MetaADEDB
beta-Methyldigoxin	30685-43-9	MetaADEDB
Bevacizumab	216974-75-3	ADReCS
Bisacodyl	603-50-9	MetaADEDB
Bucillamine	65002-17-7	MetaADEDB
Candesartan	139481-59-7	MetaADEDB
Capecitabine	154361-50-9	ADReCS
Carteolol	51781-06-7	MetaADEDB
cefpodoxime	82619-04-3	MetaADEDB
cefpodoxime proxetil	87239-81-4	MetaADEDB
Cilostazol	73963-72-1	MetaADEDB
Cisplatin	15663-27-1	MetaADEDB
Clonazepam	1622-61-3	MetaADEDB
Clopidogrel	113665-84-2	PROTECT
Cortisone	53-06-5	MetaADEDB
Dexamethasone	50-02-2	MetaADEDB
Diclofenac	15307-86-5	MetaADEDB
Diflunisal	22494-42-4	ADReCS
Difluprednate	23674-86-4	MetaADEDB
Dobutamine	34368-04-2	MetaADEDB
Docetaxel	114977-28-5	ADReCS
Domperidone	57808-66-9	MetaADEDB
Doxepin	1668-19-5	MetaADEDB
ecabet sodium	86408-72-2	MetaADEDB
Entacapone	130929-57-6	MetaADEDB
Erlotinib	183321-74-6	ADReCS
Ethanolamine	141-43-5	ADReCS
Etidronic acid	7414-83-7	ADReCS
etizolam	40054-69-1	MetaADEDB
Etodolac	41340-25-4	MetaADEDB
Fluocinonide	356-12-7	MetaADEDB
Flurbiprofen	5104-49-4	ADReCS
Fosfluconazole	194798-83-9	MetaADEDB
Fudosteine	13189-98-5	MetaADEDB
Gadoversetamide	131069-91-5	ADReCS
Ganciclovir	82410-32-0	ADReCS
Gefitinib	184475-35-2	PROTECT
Gemcitabine	95058-81-4	MetaADEDB
Glimepiride	93479-97-1	MetaADEDB
hydrocodone	125-29-1	MetaADEDB
Ibritumomab	174722-31-7	PROTECT
ibudilast	50847-11-5	MetaADEDB
Ibuprofen	15687-27-1	ADReCS
Imatinib	152459-95-5	ADReCS
Ioversol	87771-40-2	ADReCS
Ipilimumab	477202-00-9	PROTECT
Ketoprofen	22071-15-4	ADReCS
Ketorolac	66635-83-4	ADReCS
Lafutidine	118288-08-7	MetaADEDB
Letrozole	112809-51-5	MetaADEDB
Leucovorin	1492-18-8	MetaADEDB
Lisinopril	83915-83-7	MetaADEDB
Lornoxicam	70374-39-9	MetaADEDB
Loxoprofen	68767-14-6	MetaADEDB
methenolone acetate	434-05-9	MetaADEDB
Methocarbamol	532-03-6	MetaADEDB
Methylnaltrexone	73232-52-7	ADReCS
mosapride	112885-41-3	MetaADEDB
Naproxen	22204-53-1	ADReCS
Nitrazepam	146-22-5	MetaADEDB
Oxaliplatin	61825-94-3	MetaADEDB
oxatomide	60607-34-3	MetaADEDB
Oxycodone	76-42-6	MetaADEDB
Pazopanib	444731-52-6	PROTECT
Pemetrexed	137281-23-3	MetaADEDB
Pethidine	57-42-1	MetaADEDB
Piperacillin	66258-76-2	MetaADEDB
Polaprezinc	107667-60-7	MetaADEDB
Potassium Chloride	7447-40-7	ADReCS
Povidone Iodine	25655-41-8	MetaADEDB
Pravastatin	81093-37-0	MetaADEDB
Prednisone	53-03-2	MetaADEDB
Propoxyphene	469-62-5	MetaADEDB
Pyridoxal phosphate	54-47-7	MetaADEDB
Regorafenib	755037-03-7	ADReCS
Risedronate	105462-24-6	ADReCS
Sevelamer	152751-57-0	MetaADEDB
simethicone	8050-81-5	MetaADEDB
Sorafenib	284461-73-0	ADReCS
Stavudine	3056-17-5	MetaADEDB
Sulindac	38194-50-2	ADReCS
Tacrolimus	104987-11-3	ADReCS
Tegafur	17902-23-7	MetaADEDB
Thalidomide	50-35-1	ADReCS
Thiotepa	52-24-4	PROTECT
Tocilizumab	375823-41-9	ADReCS
Tolmetin	26171-23-3	ADReCS
Torasemide	56211-40-6	MetaADEDB
Tretinoin	302-79-4	MetaADEDB
Triamcinolone	124-94-7	ADReCS
Trichlormethiazide	133-67-5	MetaADEDB
Trimethobenzamide	138-56-7	MetaADEDB
Vincristine	57-22-7	ADReCS
Warfarin	81-81-2	MetaADEDB

List of proteins causing Gastrointestinal Perforation
Protein Name	Uniprot ID	Source