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Drugs Causing Extrapyramidal Disorder: 155
Drug Name
CAS Number
Source
AC-17
51460-26-5
MetaADEDB
Acebutolol
37517-30-9
MetaADEDB
Acetaminophen
103-90-2
MetaADEDB
Aldesleukin
85898-30-2
ADReCS
Alpha-Methyl-P-Tyrosine
658-48-0
ADReCS
Amisulpride
53583-79-2
MetaADEDB
Amitriptyline
50-48-6
ADReCS
Amoxapine
14028-44-5
ADReCS
Amprenavir
161814-49-9
MetaADEDB
Aripiprazole
129722-12-9
ADReCS
Arsenic trioxide
1327-53-3
MetaADEDB
Asenapine
65576-45-6
ADReCS
Atazanavir
198904-31-3
MetaADEDB
Azithromycin
83905-01-5
MetaADEDB
Baclofen
1134-47-0
MetaADEDB
beta-Methyldigoxin
30685-43-9
MetaADEDB
Binedaline
60662-16-0
MetaADEDB
buflomedil
55837-25-7
MetaADEDB
Bupropion
34841-39-9
ADReCS
Buspirone
36505-84-7
ADReCS
Carbamazepine
298-46-4
ADReCS
Carbidopa
28860-95-9
ADReCS
Chlordiazepoxide
58-25-3
ADReCS
Chlorpromazine
50-53-3
ADReCS
Cilostazol
73963-72-1
MetaADEDB
Ciprofibrate
52214-84-3
MetaADEDB
Cisapride
81098-60-4
MetaADEDB
Citalopram
59729-33-8
ADReCS
Clindamycin
18323-44-9
MetaADEDB
Clomipramine
303-49-1
ADReCS
Clozapine
5786-21-0
ADReCS
cyamemazine
3546-03-0
MetaADEDB
Cyclobenzaprine
303-53-7
ADReCS
Cyproheptadine
129-03-3
MetaADEDB
Cyproterone Acetate
427-51-0
MetaADEDB
Desflurane
57041-67-5
MetaADEDB
Desipramine
50-47-5
ADReCS
Desvenlafaxine
93413-62-8
ADReCS
Diazoxide
364-98-7
ADReCS
Digoxin
20830-75-5
MetaADEDB
dihydroergotamine
6190-39-2
MetaADEDB
Diltiazem
42399-41-7
ADReCS
Dipyridamole
58-32-2
MetaADEDB
Donepezil
120014-06-4
ADReCS
Doxepin
1668-19-5
ADReCS
Droperidol
548-73-2
ADReCS
duloxetine
136434-34-9
SIDER
Duovent
438627-66-8
MetaADEDB
Ephedrine
299-42-3
MetaADEDB
Epoprostenol
35121-78-9
MetaADEDB
Escitalopram
128196-01-0
ADReCS
ethyl loflazepate
29177-84-2
MetaADEDB
etizolam
40054-69-1
MetaADEDB
Febuxostat
144060-53-7
ADReCS
Felbamate
25451-15-4
ADReCS
Fentanyl
437-38-7
ADReCS
Flunitrazepam
1622-62-4
MetaADEDB
Fluoxetine
54910-89-3
ADReCS
Fluphenazine
69-23-8
ADReCS
Fluvoxamine
54739-18-3
ADReCS
Fosphenytoin
93390-81-9
ADReCS
Galantamine
357-70-0
MetaADEDB
Gemcitabine
95058-81-4
MetaADEDB
Granisetron
109889-09-0
ADReCS
Guanfacine
29110-47-2
MetaADEDB
Haloperidol
52-86-8
ADReCS
haloperidol decanoate
74050-97-8
MetaADEDB
Hydralazine
86-54-4
MetaADEDB
Hydroxyzine
68-88-2
MetaADEDB
Ifosfamide
3778-73-2
ADReCS
Imipramine
50-49-7
ADReCS
Interferon Alfa-2a Recombinant
76543-88-9
ADReCS
Ketorolac
66635-83-4
ADReCS
Lactulose
4618-18-2
MetaADEDB
Lamotrigine
84057-84-1
ADReCS
Levomepromazine
60-99-1
MetaADEDB
Lithium
7439-93-2
ADReCS
Loratadine
79794-75-5
MetaADEDB
Lorazepam
846-49-1
ADReCS
Maprotiline
10262-69-8
ADReCS
Meloxicam
71125-38-7
MetaADEDB
Memantine
19982-08-2
ADReCS
Meprobamate
57-53-4
MetaADEDB
Mesna
19767-45-4
MetaADEDB
Metformin
657-24-9
ADReCS
Metoclopramide
364-62-5
ADReCS
Metolazone
17560-51-9
ADReCS
Metyrosine
672-87-7
ADReCS
mianserin
24219-97-4
MetaADEDB
Milnacipran
92623-85-3
MetaADEDB
Mirtazapine
61337-67-5
ADReCS
Molindone
7416-34-4
ADReCS
Nabumetone
42924-53-8
MetaADEDB
Naloxone
465-65-6
MetaADEDB
Nefopam
13669-70-0
MetaADEDB
Nevirapine
129618-40-2
MetaADEDB
Nicergoline
27848-84-6
MetaADEDB
Nisoldipine
63675-72-9
MetaADEDB
Nitrofurantoin
67-20-9
MetaADEDB
Nortriptyline
72-69-5
ADReCS
Ofloxacin
82419-36-1
ADReCS
Olanzapine
132539-06-1
ADReCS
Ondansetron
99614-02-5
ADReCS
Oxcarbazepine
28721-07-5
ADReCS
Paliperidone
144598-75-4
ADReCS
Paroxetine
61869-08-7
ADReCS
Penicillin v
87-08-1
MetaADEDB
Pergolide
66104-22-1
ADReCS
Perphenazine
58-39-9
ADReCS
Phenytoin
57-41-0
ADReCS
Pimozide
2062-78-4
ADReCS
Piracetam
7491-74-9
MetaADEDB
Pramipexole
104632-26-0
ADReCS
Pravastatin
81093-37-0
MetaADEDB
Prazepam
2955-38-6
MetaADEDB
Prazosin
19216-56-9
MetaADEDB
Pregabalin
148553-50-8
ADReCS
Prochlorperazine
58-38-8
ADReCS
Promazine
58-40-2
MetaADEDB
Promethazine
60-87-7
ADReCS
Protriptyline
438-60-8
ADReCS
quazepam
36735-22-5
MetaADEDB
Quetiapine
111974-69-7
ADReCS
Rabeprazole
117976-89-3
ADReCS
Reserpine
50-55-5
ADReCS
Riluzole
1744-22-5
ADReCS
Risperidone
106266-06-2
ADReCS
Rivastigmine
123441-03-2
ADReCS
Ropinirole
91374-21-9
ADReCS
rosuvastatin calcium
147098-20-2
MetaADEDB
Sertraline
79617-96-2
ADReCS
Succinylcholine
306-40-1
MetaADEDB
Sumatriptan
103628-46-2
ADReCS
Tacrine
321-64-2
ADReCS
Tazarotene
118292-40-3
ADReCS
Temozolomide
85622-93-1
ADReCS
Tetrabenazine
58-46-8
ADReCS
Thioridazine
50-52-2
ADReCS
Thiotepa
52-24-4
PROTECT
Thiothixene
5591-45-7
ADReCS
Tiagabine
115103-54-3
MetaADEDB
Tianeptine
66981-73-5
MetaADEDB
Tiapride
51012-32-9
MetaADEDB
Tigecycline
220620-09-7
MetaADEDB
Tolcapone
134308-13-7
ADReCS
Trazodone
19794-93-5
ADReCS
Trifluoperazine
117-89-5
ADReCS
Trimetazidine
5011-34-7
MetaADEDB
Trimipramine
739-71-9
ADReCS
valpromide
2430-27-5
MetaADEDB
Venlafaxine
93413-69-5
ADReCS
verapamil
52-53-9
ADReCS
Voriconazole
137234-62-9
ADReCS
Ziprasidone
146939-27-7
ADReCS
Zopiclone
43200-80-2
MetaADEDB
List of proteins causing Extrapyramidal Disorder
Protein Name
Uniprot ID
Source
5-hydroxytryptamine receptor 2A
P28223
22722194
5-hydroxytryptamine receptor 2B
P41595
22722194
5-hydroxytryptamine receptor 2C precursor
P28335
22722194
5-hydroxytryptamine receptor 6
P31388
22722194
D(1A) dopamine receptor
P18901
22722194
D(1B) dopamine receptor
P21918
22722194
D(2) dopamine receptor
P14416
22722194
D(3) dopamine receptor
P35462
22722194
D(4) dopamine receptor
P21917
22722194
Histamine H1 receptor
P35367
22722194
Muscarinic acetylcholine receptor M1
P11229
22722194
Muscarinic acetylcholine receptor M2
P08172
22722194
Muscarinic acetylcholine receptor M3
P08483
22722194
Muscarinic acetylcholine receptor M4
P08485
22722194
Muscarinic acetylcholine receptor M5
P08912
22722194
Sodium-dependent serotonin transporter
P31645
22722194
Voltage-dependent T-type calcium channel subunit alpha-1H
O95180
22722194
InAADR: Drug-Protein-ADRs database