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Drugs Causing Drowsiness: 470
Drug Name
CAS Number
Source
Acebutolol
37517-30-9
SIDER
Aceclofenac
89796-99-6
SIDER
Acenocoumarol
152-72-7
MetaADEDB
Acetaminophen
103-90-2
MetaADEDB
Acetazolamide
59-66-5
SIDER
Acetylsalicylic acid
50-78-2
SIDER
Acitretin
55079-83-9
MetaADEDB
Adapalene
106685-40-9
MetaADEDB
Adenosine
58-61-7
MetaADEDB
Albendazole
54965-21-8
MetaADEDB
Alfentanil
71195-58-9
SIDER
Alfuzosin
81403-80-7
MetaADEDB
Allopurinol
315-30-0
SIDER
Alprazolam
28981-97-7
SIDER
Amantadine
768-94-5
MetaADEDB
Amezinium
41658-78-0
MetaADEDB
Amiloride Hydrochloride
2016-88-8
MetaADEDB
Aminoglutethimide
125-84-8
SIDER
Amisulpride
53583-79-2
MetaADEDB
Amitriptyline
50-48-6
SIDER
Amitriptyline Hydrochloride
549-18-8
MetaADEDB
Amlodipine
88150-42-9
MetaADEDB
Amoxapine
14028-44-5
SIDER
Amoxicillin
26787-78-0
MetaADEDB
Amphetamine
300-62-9
MetaADEDB
Ampicillin
69-53-4
MetaADEDB
Apixaban
503612-47-3
MetaADEDB
Apomorphine
58-00-4
SIDER
Apomorphine hydrochloride hemihydrate
41372-20-7
MetaADEDB
Articaine Hydrochloride
23964-57-0
SIDER
Atenolol
29122-68-7
SIDER
Atomoxetine Hydrochloride
82248-59-7
MetaADEDB
Atropine
51-55-8
SIDER
Azelastine
58581-89-8
MetaADEDB
Azithromycin
83905-01-5
MetaADEDB
Bacitracin
1405-87-4
MetaADEDB
Baclofen
1134-47-0
SIDER
Bendroflumethiazide
73-48-3
MetaADEDB
Benzatropine
86-13-5
MetaADEDB
Benzydamine
642-72-8
SIDER
beta-Acetyldigoxin
5355-48-6
MetaADEDB
Binedaline
60662-16-0
MetaADEDB
Biotin
58-85-5
MetaADEDB
Biperiden
514-65-8
SIDER
Bisacodyl
603-50-9
MetaADEDB
Bisoprolol
66722-44-9
SIDER
Bortezomib
179324-69-7
MetaADEDB
Bosentan
147536-97-8
MetaADEDB
Brimonidine
59803-98-4
SIDER
Bromazepam
1812-30-2
SIDER
Bromocriptine
25614-03-3
SIDER
Bromopride
4093-35-0
MetaADEDB
Brompheniramine
86-22-6
SIDER
Brotizolam
57801-81-7
MetaADEDB
Budesonide
51333-22-3
MetaADEDB
Bupivacaine
2180-92-9
SIDER
Buprenorphine
52485-79-7
MetaADEDB
Bupropion
34841-39-9
MetaADEDB
Buserelin acetate
68630-75-1
MetaADEDB
Buspirone
36505-84-7
SIDER
Butorphanol
42408-82-2
SIDER
Caffeine
58-08-2
MetaADEDB
Calcium
7440-70-2
MetaADEDB
Candesartan
139481-59-7
MetaADEDB
Candesartan cilexetil
145040-37-5
MetaADEDB
Captopril
62571-86-2
MetaADEDB
Carbamazepine
298-46-4
SIDER
Carbinoxamine maleate
3505-38-2
SIDER
Carisoprodol
78-44-4
SIDER
Carvedilol
72956-09-3
MetaADEDB
Cefaclor
53994-73-3
MetaADEDB
Cefadroxil
66592-87-8
SIDER
Cefepime
88040-23-7
MetaADEDB
cefpodoxime
82619-04-3
MetaADEDB
cefpodoxime proxetil
87239-81-4
MetaADEDB
Cefprozil
92665-29-7
SIDER
Cefuroxime
55268-75-2
SIDER
Cefuroxime axetil
64544-07-6
MetaADEDB
Celecoxib
169590-42-5
MetaADEDB
Celiprolol
56980-93-9
MetaADEDB
Cephalexin
15686-71-2
MetaADEDB
Cetirizine
83881-51-0
MetaADEDB
Cetraxate
34675-84-8
MetaADEDB
Chloramphenicol
56-75-7
MetaADEDB
Chlordiazepoxide
58-25-3
SIDER
Chlorhexidine
55-56-1
MetaADEDB
Chlorhexidine gluconate
18472-51-0
MetaADEDB
Chloroprocaine
133-16-4
SIDER
Chlorphenamine
132-22-9
MetaADEDB
Chlorpromazine
50-53-3
SIDER
Chlorprothixene
113-59-7
MetaADEDB
Chlorthalidone
77-36-1
MetaADEDB
Chlorzoxazone
95-25-0
SIDER
Chromium
7440-47-3
MetaADEDB
Cidofovir
113852-37-2
MetaADEDB
Cilest
79871-54-8
MetaADEDB
Cinoxacin
28657-80-9
SIDER
Ciprofloxacin
85721-33-1
SIDER
Citalopram
59729-33-8
MetaADEDB
Clemastine
15686-51-8
SIDER
Clobazam
22316-47-8
MetaADEDB
Clofazimine
2030-63-9
SIDER
Clomipramine
303-49-1
MetaADEDB
Clonazepam
1622-61-3
SIDER
Clonidine
4205-90-7
SIDER
cloxazolam
27223-35-4
MetaADEDB
Clozapine
5786-21-0
SIDER
Codeine
76-57-3
SIDER
coenzyme Q10
303-98-0
MetaADEDB
Colestipol
26658-42-4
SIDER
Cortisone
53-06-5
MetaADEDB
cyamemazine
3546-03-0
MetaADEDB
Cyclobenzaprine
303-53-7
SIDER
Cyclopentolate
512-15-2
SIDER
Cyclosporine
59865-13-3
MetaADEDB
Cyproheptadine
129-03-3
SIDER
Dantrolene
7261-97-4
SIDER
Darifenacin
133099-04-4
MetaADEDB
Deoxythymidine
50-89-5
MetaADEDB
Desipramine
50-47-5
SIDER
Desloratadine
100643-71-8
MetaADEDB
Desvenlafaxine
93413-62-8
MetaADEDB
Dexamethasone
50-02-2
MetaADEDB
dexamethasone acetate
1177-87-3
MetaADEDB
Dexrazoxane
24584-09-6
MetaADEDB
Dextromethorphan
125-71-3
MetaADEDB
Diatrizoate
117-96-4
SIDER
Diazepam
439-14-5
SIDER
diazinon
333-41-5
MetaADEDB
Diazoxide
364-98-7
SIDER
Diclofenac
15307-86-5
SIDER
Dicyclomine
77-19-0
MetaADEDB
Didanosine
69655-05-6
MetaADEDB
dihydrocodeine
125-28-0
MetaADEDB
Diltiazem
42399-41-7
MetaADEDB
dimethylpolysiloxane
9016-00-6
MetaADEDB
Diphenhydramine
58-73-1
SIDER
dipyrone
68-89-3
MetaADEDB
Distalgesic
39400-85-6
MetaADEDB
Disulfiram
97-77-8
SIDER
Dolasetron
115956-12-2
SIDER
Domperidone
57808-66-9
MetaADEDB
Donepezil
120014-06-4
MetaADEDB
Doxepin
1668-19-5
SIDER
Doxycycline
564-25-0
MetaADEDB
doxylamine
469-21-6
MetaADEDB
Droperidol
548-73-2
SIDER
duloxetine
136434-34-9
MetaADEDB
ebastine
90729-43-4
MetaADEDB
Efavirenz
154598-52-4
SIDER
Eletriptan
143322-58-1
SIDER
Enoxaparin
9005-49-6
MetaADEDB
Entacapone
130929-57-6
MetaADEDB
Esmolol
100286-90-6
MetaADEDB
Estazolam
29975-16-4
MetaADEDB
Estradiol
50-28-2
MetaADEDB
Estramustine
2998-57-4
MetaADEDB
Ethionamide
536-33-4
SIDER
Ethosuximide
77-67-8
SIDER
ethyl loflazepate
29177-84-2
MetaADEDB
etizolam
40054-69-1
MetaADEDB
Ezetimibe
163222-33-1
MetaADEDB
Famotidine
76824-35-6
MetaADEDB
Fenofibrate
49562-28-9
MetaADEDB
Fenoterol
13392-18-2
MetaADEDB
Fentanyl
437-38-7
SIDER
Fexofenadine
83799-24-0
SIDER
Finasteride
98319-26-7
MetaADEDB
Fioricet
122018-95-5
MetaADEDB
Flavoxate
15301-69-6
SIDER
Fludrocortisone
127-31-1
MetaADEDB
Fludrocortisone acetate
514-36-3
MetaADEDB
Flumazenil
78755-81-4
SIDER
Flunitrazepam
1622-62-4
MetaADEDB
Fluocinonide
356-12-7
MetaADEDB
Fluoxetine
54910-89-3
SIDER
Fluphenazine
69-23-8
SIDER
Flupirtine
56995-20-1
MetaADEDB
Flurazepam
17617-23-1
SIDER
Flurbiprofen
5104-49-4
SIDER
Flutamide
13311-84-7
SIDER
Fluvoxamine
54739-18-3
MetaADEDB
Fosinopril
98048-97-6
SIDER
Fulvestrant
129453-61-8
MetaADEDB
Furosemide
54-31-9
SIDER
Gabapentin
60142-96-3
MetaADEDB
Galantamine
357-70-0
MetaADEDB
Gliclazide
21187-98-4
SIDER
Glipizide
29094-61-9
SIDER
Glutamine
56-85-9
MetaADEDB
Glyburide
10238-21-8
MetaADEDB
glycerol
56-81-5
MetaADEDB
Glycopyrrolate
596-51-0
SIDER
Guanfacine
29110-47-2
SIDER
Halobetasol Propionate
66852-54-8
MetaADEDB
Haloperidol
52-86-8
SIDER
Hydralazine
86-54-4
MetaADEDB
hydrocodone
125-29-1
MetaADEDB
Hydromorphone
466-99-9
SIDER
Hydroxyurea
127-07-1
SIDER
Hydroxyzine
68-88-2
SIDER
Ibuprofen
15687-27-1
SIDER
Ifosfamide
3778-73-2
MetaADEDB
iloprost
78919-13-8
MetaADEDB
Imipramine
50-49-7
SIDER
Indapamide
26807-65-8
SIDER
Indomethacin
53-86-1
SIDER
Iodine
7553-56-2
SIDER
Iodixanol
92339-11-2
SIDER
Ioversol
87771-40-2
SIDER
Ipratropium bromide
22254-24-6
SIDER
Isocarboxazid
59-63-2
SIDER
Isoflurane
26675-46-7
MetaADEDB
Ixabepilone
219989-84-1
MetaADEDB
Ketoconazole
65277-42-1
MetaADEDB
Ketoprofen
22071-15-4
SIDER
Ketorolac
66635-83-4
SIDER
Ketotifen
34580-14-8
MetaADEDB
L-Carnitine
541-15-1
MetaADEDB
L-Tryptophan
73-22-3
MetaADEDB
Labetalol
36894-69-6
SIDER
Lacidipine
103890-78-4
MetaADEDB
Lactulose
4618-18-2
MetaADEDB
Lapatinib
231277-92-2
MetaADEDB
Levetiracetam
102767-28-2
MetaADEDB
Levobunolol
47141-42-4
MetaADEDB
Levocabastine
79516-68-0
MetaADEDB
Levodopa
59-92-7
MetaADEDB
Levomepromazine
60-99-1
MetaADEDB
Lidocaine
137-58-6
SIDER
Limaprost
74397-12-9
MetaADEDB
Lithium
7439-93-2
SIDER
Lomotil
55840-97-6
MetaADEDB
Loperamide
53179-11-6
SIDER
Lopinavir
192725-17-0
MetaADEDB
Loratadine
79794-75-5
SIDER
Lorazepam
846-49-1
MetaADEDB
Losartan
114798-26-4
MetaADEDB
Loxoprofen
68767-14-6
MetaADEDB
Lutein
127-40-2
MetaADEDB
Maprotiline
10262-69-8
MetaADEDB
Medroxyprogesterone
520-85-4
SIDER
Mefenamic acid
61-68-7
SIDER
Mefloquine
53230-10-7
MetaADEDB
Megestrol
3562-63-8
MetaADEDB
melatonin
73-31-4
MetaADEDB
Meloxicam
71125-38-7
SIDER
melperone
3575-80-2
MetaADEDB
Memantine
19982-08-2
MetaADEDB
Mephenytoin
50-12-4
SIDER
Mepivacaine
96-88-8
SIDER
Meprobamate
57-53-4
SIDER
Mesna
19767-45-4
MetaADEDB
Mesoridazine
5588-33-0
SIDER
Metaxalone
1665-48-1
MetaADEDB
Metformin
657-24-9
SIDER
Methadone
76-99-3
MetaADEDB
Methazolamide
554-57-4
SIDER
methenolone acetate
434-05-9
MetaADEDB
Methimazole
60-56-0
SIDER
Methocarbamol
532-03-6
SIDER
Methotrexate
59-05-2
SIDER
Methsuximide
77-41-8
SIDER
Methyldopa
555-30-6
MetaADEDB
Methylergometrine
113-42-8
MetaADEDB
Methylphenidate
113-45-1
SIDER
Methysergide
361-37-5
SIDER
Metoclopramide
364-62-5
SIDER
Metolazone
17560-51-9
SIDER
Metoprolol
37350-58-6
MetaADEDB
Metronidazole
443-48-1
SIDER
Mexiletine
31828-71-4
SIDER
mianserin
24219-97-4
MetaADEDB
Midazolam
59467-70-8
SIDER
Midodrine
133163-28-7
MetaADEDB
Milnacipran
92623-85-3
MetaADEDB
Minocycline
10118-90-8
MetaADEDB
Misoprostol
59122-46-2
SIDER
Mitotane
53-19-0
MetaADEDB
Mitoxantrone
65271-80-9
SIDER
moclobemide
71320-77-9
MetaADEDB
Modafinil
68693-11-8
MetaADEDB
Moexipril
103775-10-6
SIDER
Molindone
7416-34-4
SIDER
Montelukast
158966-92-8
SIDER
montelukast sodium
151767-02-1
MetaADEDB
Morphine
57-27-2
SIDER
Moxifloxacin
151096-09-2
MetaADEDB
Mupirocin
12650-69-0
MetaADEDB
Mycophenolic acid
24280-93-1
MetaADEDB
Nabilone
51022-71-0
SIDER
Nabumetone
42924-53-8
MetaADEDB
Nadolol
42200-33-9
MetaADEDB
Nafronyl
31329-57-4
MetaADEDB
Nalbuphine
20594-83-6
MetaADEDB
Nalidixic Acid
389-08-2
SIDER
Naloxone
465-65-6
MetaADEDB
Naltrexone
16590-41-3
MetaADEDB
Naphazoline
835-31-4
SIDER
Naproxen
22204-53-1
SIDER
Naratriptan
121679-13-8
SIDER
Nelarabine
121032-29-9
MetaADEDB
Neomycin
1404-04-2
MetaADEDB
Neostigmine
59-99-4
SIDER
Nicergoline
27848-84-6
MetaADEDB
Nilutamide
63612-50-0
SIDER
Nitrazepam
146-22-5
SIDER
Nitrendipine
39562-70-4
MetaADEDB
Nitrofurantoin
67-20-9
SIDER
Norethindrone
68-22-4
MetaADEDB
Norfloxacin
70458-96-7
SIDER
Nortriptyline
72-69-5
SIDER
Nystatin
1400-61-9
MetaADEDB
Octreotide
83150-76-9
MetaADEDB
Olanzapine
132539-06-1
MetaADEDB
olmesartan medoxomil
144689-63-4
MetaADEDB
Olopatadine
113806-05-6
MetaADEDB
Olsalazine
15722-48-2
SIDER
Omeprazole
73590-58-6
MetaADEDB
Ondansetron
99614-02-5
SIDER
opipramol
315-72-0
MetaADEDB
Orphenadrine
83-98-7
SIDER
Oxaprozin
21256-18-8
SIDER
oxatomide
60607-34-3
MetaADEDB
Oxazepam
604-75-1
SIDER
Oxcarbazepine
28721-07-5
MetaADEDB
Oxycodone
76-42-6
MetaADEDB
Pantoprazole
102625-70-7
MetaADEDB
Paroxetine
61869-08-7
MetaADEDB
Pemoline
2152-34-3
SIDER
Penicillin v
87-08-1
MetaADEDB
Perphenazine
58-39-9
SIDER
Pethidine
57-42-1
MetaADEDB
Phenacetin
62-44-2
MetaADEDB
Phenelzine
51-71-8
SIDER
Phenethicillin
147-55-7
MetaADEDB
Phenobarbital
50-06-6
SIDER
Phenoxybenzamine
59-96-1
SIDER
Phentermine
122-09-8
MetaADEDB
Phenytoin
57-41-0
MetaADEDB
Phosphorus
7723-14-0
MetaADEDB
Pilsicainide
88069-67-4
MetaADEDB
Pimecrolimus
137071-32-0
MetaADEDB
Pimozide
2062-78-4
MetaADEDB
Pinaverium Bromide
53251-94-8
MetaADEDB
Pindolol
13523-86-9
SIDER
Pipamperone
1893-33-0
MetaADEDB
Piracetam
7491-74-9
MetaADEDB
Pirbuterol
38677-81-5
SIDER
Pirenzepine
28797-61-7
MetaADEDB
Piroxicam
36322-90-4
SIDER
Pitavastatin
147511-69-1
MetaADEDB
Pizotifen
15574-96-6
SIDER
Polymyxin B Sulfate
1405-20-5
SIDER
Posaconazole
171228-49-2
MetaADEDB
Pralidoxime
6735-59-7
SIDER
Pramipexole
104632-26-0
MetaADEDB
Prazepam
2955-38-6
MetaADEDB
Praziquantel
55268-74-1
SIDER
Prazosin
19216-56-9
SIDER
Pregabalin
148553-50-8
MetaADEDB
Prilocaine
721-50-6
SIDER
Primidone
125-33-7
SIDER
Procaine
59-46-1
SIDER
Procarbazine
671-16-9
SIDER
Prochlorperazine
58-38-8
SIDER
Procyclidine
77-37-2
MetaADEDB
Progesterone
57-83-0
SIDER
Promazine
58-40-2
MetaADEDB
Promethazine
60-87-7
SIDER
Propafenone
54063-53-5
SIDER
Propericiazine
2622-26-6
MetaADEDB
Propoxyphene
469-62-5
MetaADEDB
Propranolol
525-66-6
SIDER
Propylthiouracil
51-52-5
SIDER
Prothipendyl
303-69-5
MetaADEDB
Protriptyline
438-60-8
SIDER
Pyrazinamide
98-96-4
MetaADEDB
Pyridostigmine
155-97-5
SIDER
Pyridoxine
65-23-6
MetaADEDB
quazepam
36735-22-5
MetaADEDB
Quetiapine
111974-69-7
MetaADEDB
Quinapril
85441-61-8
MetaADEDB
Repaglinide
135062-02-1
MetaADEDB
Reserpine
50-55-5
SIDER
Rifampicin
13292-46-1
SIDER
Risedronate
105462-24-6
MetaADEDB
Risperidone
106266-06-2
SIDER
Rizatriptan
145202-66-0
MetaADEDB
Ropinirole
91374-21-9
MetaADEDB
Ropivacaine
84057-95-4
SIDER
rosuvastatin calcium
147098-20-2
MetaADEDB
roxatidine acetate
78628-28-1
MetaADEDB
Salbutamol
18559-94-9
SIDER
Salicylic Acid
69-72-7
SIDER
Salmeterol
89365-50-4
MetaADEDB
scopolamine
51-34-3
MetaADEDB
Selegiline
14611-51-9
SIDER
Silver sulfadiazine
22199-08-2
MetaADEDB
Solifenacin
242478-37-1
MetaADEDB
Spironolactone
52-01-7
SIDER
Sucralfate
54182-58-0
SIDER
sulfamethoxazole
723-46-6
MetaADEDB
Sulfasalazine
599-79-1
SIDER
Sulfisoxazole
127-69-5
SIDER
sulpiride
15676-16-1
MetaADEDB
Sumatriptan
103628-46-2
SIDER
Tamsulosin
106133-20-4
MetaADEDB
Tandospirone
112457-95-1
MetaADEDB
Telithromycin
191114-48-4
MetaADEDB
Temazepam
846-50-4
SIDER
Tenoxicam
59804-37-4
MetaADEDB
Terazosin
63590-64-7
MetaADEDB
Terbutaline
23031-25-6
SIDER
Tetrabenazine
58-46-8
MetaADEDB
Tetracaine
94-24-6
SIDER
Tetrahydrobiopterin
17528-72-2
MetaADEDB
Tetrazepam
10379-14-3
MetaADEDB
Thalidomide
50-35-1
MetaADEDB
Theophylline
58-55-9
MetaADEDB
Thiabendazole
148-79-8
SIDER
Thiamine
59-43-8
MetaADEDB
Thiethylperazine
1420-55-9
MetaADEDB
Thioridazine
50-52-2
SIDER
Thiotepa
52-24-4
MetaADEDB
Thiothixene
5591-45-7
SIDER
Tianeptine
66981-73-5
MetaADEDB
Tiapride
51012-32-9
MetaADEDB
Tilidine
51931-66-9
MetaADEDB
Tinidazole
19387-91-8
SIDER
Tipepidine hibenzate
31139-87-4
MetaADEDB
Tizanidine
51322-75-9
SIDER
Tolbutamide
64-77-7
MetaADEDB
Tolmetin
26171-23-3
SIDER
Torasemide
56211-40-6
MetaADEDB
Tramadol
27203-92-5
MetaADEDB
Trandolapril
87679-37-6
SIDER
Tranylcypromine
155-09-9
MetaADEDB
Trazodone
19794-93-5
SIDER
Tretinoin
302-79-4
SIDER
Triamcinolone
124-94-7
MetaADEDB
Triamcinolone acetonide
76-25-5
MetaADEDB
Triamterene
396-01-0
MetaADEDB
Triazolam
28911-01-5
SIDER
Trifluoperazine
117-89-5
SIDER
Trihexyphenidyl
144-11-6
SIDER
Trimebutine
39133-31-8
MetaADEDB
Trimetazidine
5011-34-7
MetaADEDB
Trimethobenzamide
138-56-7
MetaADEDB
Trimipramine
739-71-9
MetaADEDB
valacyclovir
124832-27-5
MetaADEDB
Valproic Acid
99-66-1
SIDER
Valsartan
137862-53-4
MetaADEDB
Varenicline
249296-44-4
MetaADEDB
Venlafaxine
93413-69-5
MetaADEDB
verapamil
52-53-9
SIDER
Vigabatrin
60643-86-9
SIDER
Vincristine
57-22-7
MetaADEDB
vindesine
59917-39-4
MetaADEDB
Vitamin A
68-26-8
MetaADEDB
voglibose
83480-29-9
MetaADEDB
Voriconazole
137234-62-9
MetaADEDB
Zafirlukast
107753-78-6
MetaADEDB
Zaleplon
151319-34-5
MetaADEDB
zinc
7440-66-6
MetaADEDB
Ziprasidone
146939-27-7
MetaADEDB
Zolpidem
82626-48-0
SIDER
Zonisamide
68291-97-4
MetaADEDB
Zopiclone
43200-80-2
SIDER
zuclopenthixol
53772-83-1
MetaADEDB
List of proteins causing Drowsiness
Protein Name
Uniprot ID
Source
InAADR: Drug-Protein-ADRs database