Drugs Causing Dependence: 137
Drug Name	CAS Number	Source
Alprazolam	28981-97-7	ADReCS
Amitriptyline	50-48-6	ADReCS
Amoxicillin	26787-78-0	MetaADEDB
Azelastine	58581-89-8	MetaADEDB
Azithromycin	83905-01-5	MetaADEDB
Baclofen	1134-47-0	MetaADEDB
Bromazepam	1812-30-2	MetaADEDB
Budesonide	51333-22-3	MetaADEDB
Buprenorphine	52485-79-7	ADReCS
Bupropion	34841-39-9	ADReCS
Butorphanol	42408-82-2	MetaADEDB
Cefaclor	53994-73-3	MetaADEDB
Cefuroxime	55268-75-2	MetaADEDB
Cefuroxime axetil	64544-07-6	MetaADEDB
Cetirizine	83881-51-0	MetaADEDB
Chlordiazepoxide	58-25-3	MetaADEDB
Chlorpromazine	50-53-3	MetaADEDB
Chlorzoxazone	95-25-0	MetaADEDB
Ciclopirox	29342-05-0	MetaADEDB
Cidofovir	113852-37-2	MetaADEDB
Cimetidine	51481-61-9	MetaADEDB
Cisapride	81098-60-4	MetaADEDB
Citalopram	59729-33-8	MetaADEDB
Clomiphene citrate	50-41-9	MetaADEDB
Clonazepam	1622-61-3	ADReCS
Clozapine	5786-21-0	MetaADEDB
Cyclobenzaprine	303-53-7	ADReCS
Cyproheptadine	129-03-3	MetaADEDB
Darifenacin	133099-04-4	MetaADEDB
Deoxythymidine	50-89-5	MetaADEDB
Desipramine	50-47-5	ADReCS
Desloratadine	100643-71-8	MetaADEDB
Diazepam	439-14-5	ADReCS
Dicyclomine	77-19-0	ADReCS
dihydroergotamine	6190-39-2	MetaADEDB
dihydroxyaluminum sodium carbonate	41342-54-5	MetaADEDB
Diphenhydramine	58-73-1	MetaADEDB
dothiepin	113-53-1	MetaADEDB
Doxepin	1668-19-5	ADReCS
Doxycycline	564-25-0	MetaADEDB
doxylamine	469-21-6	MetaADEDB
duloxetine	136434-34-9	MetaADEDB
Estradiol	50-28-2	MetaADEDB
Famotidine	76824-35-6	MetaADEDB
Fenofibrate	49562-28-9	MetaADEDB
Fentanyl	437-38-7	ADReCS
Fioricet	122018-95-5	MetaADEDB
Flumazenil	78755-81-4	MetaADEDB
Flupenthixol	2709-56-0	MetaADEDB
Fluphenazine	69-23-8	MetaADEDB
Fluphenazine decanoate	5002-47-1	MetaADEDB
Flurazepam	17617-23-1	MetaADEDB
Fluticasone Propionate	80474-14-2	MetaADEDB
Fluvoxamine	54739-18-3	MetaADEDB
Formoterol	73573-87-2	MetaADEDB
Gabapentin	60142-96-3	MetaADEDB
heroin	561-27-3	MetaADEDB
Hydromorphone	466-99-9	ADReCS
hydroxyzine pamoate	10246-75-0	MetaADEDB
Imipramine	50-49-7	ADReCS
Indinavir	150378-17-9	MetaADEDB
Ketamine	6740-88-1	MetaADEDB
L-Carnitine	541-15-1	MetaADEDB
Lamivudine	134678-17-4	MetaADEDB
Leflunomide	75706-12-6	MetaADEDB
Levetiracetam	102767-28-2	MetaADEDB
Loratadine	79794-75-5	MetaADEDB
Meloxicam	71125-38-7	MetaADEDB
Methadone	76-99-3	ADReCS
Methamphetamine	537-46-2	MetaADEDB
Methocarbamol	532-03-6	MetaADEDB
Methylphenidate	113-45-1	MetaADEDB
Methyltestosterone	58-18-4	MetaADEDB
Metoclopramide	364-62-5	MetaADEDB
Mirtazapine	61337-67-5	MetaADEDB
Modafinil	68693-11-8	MetaADEDB
montelukast sodium	151767-02-1	MetaADEDB
Morphine	57-27-2	ADReCS
Nabumetone	42924-53-8	MetaADEDB
Nalbuphine	20594-83-6	MetaADEDB
Naloxone	465-65-6	MetaADEDB
Naproxen	22204-53-1	MetaADEDB
Naratriptan	121679-13-8	MetaADEDB
Nelfinavir	159989-64-7	MetaADEDB
Nicotine	54-11-5	ADReCS
Nitrofurantoin	67-20-9	MetaADEDB
Nortriptyline	72-69-5	ADReCS
Olanzapine	132539-06-1	MetaADEDB
Olopatadine	113806-05-6	MetaADEDB
Orphenadrine	83-98-7	MetaADEDB
Oxycodone	76-42-6	ADReCS
oxymetazoline	1491-59-4	MetaADEDB
Paroxetine	61869-08-7	ADReCS
Pentazocine	359-83-1	MetaADEDB
Pethidine	57-42-1	MetaADEDB
Phenacetin	62-44-2	MetaADEDB
Phenelzine	51-71-8	MetaADEDB
Phentermine	122-09-8	MetaADEDB
Pramipexole	104632-26-0	MetaADEDB
Pregabalin	148553-50-8	ADReCS
Prochlorperazine	58-38-8	ADReCS
Propofol	2078-54-8	MetaADEDB
Propoxyphene	469-62-5	MetaADEDB
Propoxyphene napsylate	17140-78-2	MetaADEDB
Protriptyline	438-60-8	ADReCS
Pyridoxine	65-23-6	MetaADEDB
quazepam	36735-22-5	MetaADEDB
Quetiapine	111974-69-7	ADReCS
Rabeprazole	117976-89-3	ADReCS
Remifentanil	132875-61-7	MetaADEDB
Ribavirin	36791-04-5	MetaADEDB
Rizatriptan	145202-66-0	MetaADEDB
Ropinirole	91374-21-9	MetaADEDB
Saquinavir	127779-20-8	MetaADEDB
Silver sulfadiazine	22199-08-2	MetaADEDB
Solifenacin	242478-37-1	MetaADEDB
Sulfadiazine	68-35-9	MetaADEDB
Sumatriptan	103628-46-2	MetaADEDB
Tacrolimus	104987-11-3	MetaADEDB
Tapentadol	175591-23-8	MetaADEDB
Temazepam	846-50-4	MetaADEDB
Testosterone	58-22-0	MetaADEDB
Thioridazine	50-52-2	MetaADEDB
Thiothixene	5591-45-7	MetaADEDB
Tizanidine	51322-75-9	MetaADEDB
Tolazamide	1156-19-0	ADReCS
Tolterodine	124937-51-5	MetaADEDB
Topiramate	97240-79-4	MetaADEDB
Tramadol	27203-92-5	MetaADEDB
Triamcinolone	124-94-7	MetaADEDB
Triamcinolone acetonide	76-25-5	MetaADEDB
Triazolam	28911-01-5	MetaADEDB
Trifluoperazine	117-89-5	ADReCS
Trimethobenzamide	138-56-7	MetaADEDB
Venlafaxine	93413-69-5	MetaADEDB
Zaleplon	151319-34-5	PROTECT
Zopiclone	43200-80-2	MetaADEDB

List of proteins causing Dependence
Protein Name	Uniprot ID	Source
delta-Type opioid receptor	P41143	22722194
Gamma-aminobutyric acid receptor subunit alpha-1 precursor	P14867	22722194
Gamma-aminobutyric acid receptor subunit alpha-2 precursor	P47869	22722194
Gamma-aminobutyric acid receptor subunit alpha-3 precursor	P34903	22722194
Gamma-aminobutyric acid receptor subunit alpha-4 precursor	P48169	22722194
Gamma-aminobutyric acid receptor subunit alpha-5 precursor	P31644	22722194
Gamma-aminobutyric acid receptor subunit alpha-6 precursor	P30191	22722194
Gamma-aminobutyric acid receptor subunit beta-1 precursor	P15431	22722194
Gamma-aminobutyric acid receptor subunit beta-2 precursor	P63138	22722194
Gamma-aminobutyric acid receptor subunit beta-3 precursor	P28472	22722194
gamma-aminobutyric acid receptor subunit delta precursor	O14764	22722194
gamma-aminobutyric acid receptor subunit epsilon precursor	P78334	22722194
Gamma-aminobutyric acid receptor subunit gamma-1 precursor	Q8N1C3	22722194
Gamma-aminobutyric acid receptor subunit gamma-2 precursor	P18507	22722194
Gamma-aminobutyric acid receptor subunit gamma-3 precursor	Q99928	22722194
gamma-aminobutyric acid receptor subunit pi precursor	O00591	22722194
gamma-aminobutyric acid receptor subunit theta precursor	Q9UN88	22722194
Kappa-Type opioid receptor	P41145	22722194
Mu-Type opioid receptor	P35372	22722194
Sigma non-opioid intracellular receptor 1	Q99720	22722194
Sodium-dependent serotonin transporter	P31645	22722194
Tryptophan-rich sensory protein	Q9RFC8	22722194