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Enter Adverse Drug Reaction Name:
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Drugs Causing Cholestasis: 227
Drug Name
CAS Number
Source
Acenocoumarol
152-72-7
MetaADEDB
Acetaminophen
103-90-2
MetaADEDB
Acetohexamide
968-81-0
MetaADEDB
Acetylsalicylic acid
50-78-2
MetaADEDB
Acitretin
55079-83-9
MetaADEDB
Adenine
73-24-5
MetaADEDB
Agmatine
306-60-5
MetaADEDB
Alfuzosin
81403-80-7
ADReCS
Almitrine
27469-53-0
MetaADEDB
Alprostadil
745-65-3
MetaADEDB
Amiodarone
1951-25-3
MetaADEDB
Amitriptyline Hydrochloride
549-18-8
MetaADEDB
Amlodipine
88150-42-9
ADReCS
Amoxicillin
26787-78-0
ADReCS
Amoxicillin-Potassium Clavulanate Combination
61336-70-7
MetaADEDB
Amphotericin B
1397-89-3
ADReCS
Ampicillin
69-53-4
MetaADEDB
Anidulafungin
166663-25-8
ADReCS
Atazanavir
198904-31-3
ADReCS
Atenolol
29122-68-7
ADReCS
Atorvastatin
134523-00-5
ADReCS
Azathioprine
446-86-6
MetaADEDB
Bepridil
64706-54-3
MetaADEDB
Bezafibrate
41859-67-0
ADReCS
Bleomycin
11056-06-7
ADReCS
Bortezomib
179324-69-7
ADReCS
Bucladesine
362-74-3
MetaADEDB
Bupivacaine
2180-92-9
MetaADEDB
Bupropion
34841-39-9
MetaADEDB
Busulfan
55-98-1
MetaADEDB
Butorphanol
42408-82-2
MetaADEDB
Captopril
62571-86-2
ADReCS
Carbamazepine
298-46-4
MetaADEDB
Carbimazole
22232-54-8
MetaADEDB
Carmustine
154-93-8
MetaADEDB
Caspofungin
179463-17-3
PROTECT
Cefaclor
53994-73-3
ADReCS
Cefadroxil
66592-87-8
ADReCS
Cefazolin
25953-19-9
ADReCS
Cefdinir
91832-40-5
ADReCS
Cefditoren
104145-95-1
ADReCS
Cefepime
88040-23-7
ADReCS
Cefixime
79350-37-1
ADReCS
Cefotaxime
63527-52-6
ADReCS
Cefotetan
69712-56-7
ADReCS
Cefoxitin
35607-66-0
ADReCS
cefpodoxime
82619-04-3
SIDER
Ceftazidime
78439-06-2
SIDER
Ceftibuten
97519-39-6
ADReCS
Ceftriaxone
73384-59-5
ADReCS
Cefuroxime
55268-75-2
ADReCS
Cephalexin
15686-71-2
MetaADEDB
cephem
CASNA513
SIDER
Cetirizine
83881-51-0
ADReCS
Chlorambucil
305-03-3
MetaADEDB
Chlordiazepoxide
58-25-3
MetaADEDB
Chlormezanone
80-77-3
MetaADEDB
Chlorpromazine
50-53-3
MetaADEDB
Chlorpropamide
94-20-2
MetaADEDB
Chlorprothixene
113-59-7
MetaADEDB
Cholesterol
57-88-5
MetaADEDB
Cimetidine
51481-61-9
MetaADEDB
cinnarizine
298-57-7
MetaADEDB
Ciprofloxacin
85721-33-1
MetaADEDB
Citalopram
59729-33-8
MetaADEDB
Clarithromycin
81103-11-9
MetaADEDB
clavulanic acid
58001-44-8
MetaADEDB
Clindamycin
18323-44-9
MetaADEDB
Clotrimazole
23593-75-1
MetaADEDB
cloxacillin
61-72-3
MetaADEDB
Clozapine
5786-21-0
ADReCS
Cod Liver Oil
8001-69-2
MetaADEDB
Colchicine
64-86-8
MetaADEDB
Cyclobenzaprine
303-53-7
ADReCS
Cyclophosphamide
50-18-0
MetaADEDB
Cyclosporine
59865-13-3
MetaADEDB
Cyproheptadine
129-03-3
ADReCS
Cyproterone Acetate
427-51-0
MetaADEDB
Cytarabine
147-94-4
MetaADEDB
Danazol
17230-88-5
MetaADEDB
Dantrolene
7261-97-4
MetaADEDB
Dapsone
80-08-0
MetaADEDB
Darunavir
206361-99-1
ADReCS
Dasatinib
302962-49-8
ADReCS
Daunorubicin
20830-81-3
MetaADEDB
Desflurane
57041-67-5
ADReCS
Dextromethorphan
125-71-3
MetaADEDB
Diclofenac
15307-86-5
MetaADEDB
Dicloxacillin
3116-76-5
MetaADEDB
Dicumarol
66-76-2
MetaADEDB
Diflunisal
22494-42-4
ADReCS
Dipyridamole
58-32-2
MetaADEDB
dipyrone
68-89-3
MetaADEDB
dothiepin
113-53-1
MetaADEDB
Doxazosin
74191-85-8
ADReCS
Doxorubicin
23214-92-8
MetaADEDB
Eltrombopag
496775-61-2
PROTECT
Enalapril
75847-73-3
MetaADEDB
Enflurane
13838-16-9
MetaADEDB
Enoxaparin
9005-49-6
MetaADEDB
Ethinyl Estradiol
57-63-6
MetaADEDB
Famotidine
76824-35-6
MetaADEDB
Flecainide
54143-55-4
ADReCS
Floxacillin
5250-39-5
MetaADEDB
Floxuridine
50-91-9
MetaADEDB
Fluconazole
86386-73-4
ADReCS
Flurbiprofen
5104-49-4
MetaADEDB
Flutamide
13311-84-7
MetaADEDB
Ganciclovir
82410-32-0
ADReCS
Gliclazide
21187-98-4
ADReCS
Glimepiride
93479-97-1
ADReCS
glutathione
70-18-8
MetaADEDB
Glyburide
10238-21-8
ADReCS
Griseofulvin
126-07-8
MetaADEDB
Halothane
151-67-7
MetaADEDB
Hydralazine
86-54-4
MetaADEDB
Ibuprofen
15687-27-1
ADReCS
Ifosfamide
3778-73-2
ADReCS
Imipramine
50-49-7
MetaADEDB
Indomethacin
53-86-1
MetaADEDB
Infliximab
170277-31-3
ADReCS
Iron
7439-89-6
MetaADEDB
Isoflurane
26675-46-7
MetaADEDB
Itraconazole
84625-61-6
MetaADEDB
Ketoconazole
65277-42-1
MetaADEDB
Leflunomide
75706-12-6
ADReCS
Lenalidomide
191732-72-6
PROTECT
Levocetirizine
130018-77-8
ADReCS
Levonorgestrel
797-63-7
MetaADEDB
Lomustine
13010-47-4
MetaADEDB
Loracarbef
76470-66-1
ADReCS
Lovastatin
75330-75-5
MetaADEDB
Mefloquine
53230-10-7
MetaADEDB
melatonin
73-31-4
MetaADEDB
Memantine
19982-08-2
MetaADEDB
Mercaptopurine
50-44-2
PROTECT
Meropenem
119478-56-7
ADReCS
Mesalazine
89-57-6
MetaADEDB
Mesoridazine
5588-33-0
MetaADEDB
Metformin
657-24-9
MetaADEDB
Methamphetamine
537-46-2
MetaADEDB
Methimazole
60-56-0
MetaADEDB
Methotrexate
59-05-2
MetaADEDB
Methylcholanthrene
56-49-5
MetaADEDB
Methyldopa
555-30-6
MetaADEDB
Methylprednisolone
83-43-2
MetaADEDB
Methyltestosterone
58-18-4
MetaADEDB
Metoclopramide
364-62-5
MetaADEDB
Metolazone
17560-51-9
MetaADEDB
Metronidazole
443-48-1
MetaADEDB
Mezlocillin
51481-65-3
MetaADEDB
Micafungin
235114-32-6
PROTECT
Minocycline
10118-90-8
ADReCS
Mitoxantrone
65271-80-9
MetaADEDB
Morphine
57-27-2
MetaADEDB
Nalbuphine
20594-83-6
MetaADEDB
Nalidixic Acid
389-08-2
ADReCS
Naproxen
22204-53-1
ADReCS
Nelfinavir
159989-64-7
MetaADEDB
Niacin
59-67-6
MetaADEDB
Nifedipine
21829-25-4
ADReCS
Nilotinib
641571-10-0
ADReCS
Nitric Oxide
10102-43-9
MetaADEDB
Nitrofurantoin
67-20-9
MetaADEDB
Norethindrone
68-22-4
MetaADEDB
Norfloxacin
70458-96-7
ADReCS
Octreotide
83150-76-9
ADReCS
Ofloxacin
82419-36-1
MetaADEDB
Omeprazole
73590-58-6
ADReCS
Oxacillin
66-79-5
MetaADEDB
Oxycodone
76-42-6
ADReCS
Oxymetholone
434-07-1
MetaADEDB
Paclitaxel
33069-62-4
MetaADEDB
Paroxetine
61869-08-7
MetaADEDB
Penicillamine
52-67-5
ADReCS
Perphenazine
58-39-9
ADReCS
Pethidine
57-42-1
MetaADEDB
Phenobarbital
50-06-6
MetaADEDB
Phenprocoumon
435-97-2
MetaADEDB
Phenylbutazone
50-33-9
MetaADEDB
Phenytoin
57-41-0
MetaADEDB
Piperacillin
66258-76-2
MetaADEDB
Piroxicam
36322-90-4
MetaADEDB
Posaconazole
171228-49-2
ADReCS
Prajmaline
35080-11-6
MetaADEDB
Pravastatin
81093-37-0
MetaADEDB
Prednisone
53-03-2
MetaADEDB
Prochlorperazine
58-38-8
ADReCS
Progesterone
57-83-0
ADReCS
Propafenone
54063-53-5
ADReCS
Propylthiouracil
51-52-5
MetaADEDB
Quinidine
56-54-2
MetaADEDB
Ranitidine
66357-35-5
ADReCS
Rifampicin
13292-46-1
MetaADEDB
Riluzole
1744-22-5
ADReCS
Risperidone
106266-06-2
MetaADEDB
Ritonavir
155213-67-5
MetaADEDB
Rivaroxaban
366789-02-8
ADReCS
S-Adenosylmethionine
29908-03-0
MetaADEDB
Simvastatin
79902-63-9
MetaADEDB
Sitaxentan
210421-64-0
MetaADEDB
Soybean Oil
8001-22-7
ADReCS
sulfamethoxazole
723-46-6
MetaADEDB
Sulfasalazine
599-79-1
MetaADEDB
Sulindac
38194-50-2
ADReCS
sulpiride
15676-16-1
MetaADEDB
Tacrolimus
104987-11-3
MetaADEDB
Tamoxifen
10540-29-1
ADReCS
Teduglutide
197922-42-2
PROTECT
Temozolomide
85622-93-1
ADReCS
Terfenadine
50679-08-8
MetaADEDB
Tetracycline
60-54-8
MetaADEDB
Thalidomide
50-35-1
ADReCS
Thiabendazole
148-79-8
ADReCS
Thioridazine
50-52-2
ADReCS
Ticlopidine
55142-85-3
MetaADEDB
Tigecycline
220620-09-7
ADReCS
Tocopherols
59-02-9
MetaADEDB
Trazodone
19794-93-5
ADReCS
Trifluoperazine
117-89-5
ADReCS
Ursodeoxycholic acid
128-13-2
MetaADEDB
Valproic Acid
99-66-1
MetaADEDB
verapamil
52-53-9
ADReCS
Vigabatrin
60643-86-9
ADReCS
Vitamin A
68-26-8
MetaADEDB
Voriconazole
137234-62-9
ADReCS
Warfarin
81-81-2
ADReCS
List of proteins causing Cholestasis
Protein Name
Uniprot ID
Source
D(1A) dopamine receptor
P18901
22722194
D(2) dopamine receptor
P14416
22722194
Gamma-aminobutyric acid receptor subunit alpha-1 precursor
P14867
22722194
Gamma-aminobutyric acid receptor subunit alpha-2 precursor
P47869
22722194
Gamma-aminobutyric acid receptor subunit alpha-3 precursor
P34903
22722194
Gamma-aminobutyric acid receptor subunit alpha-4 precursor
P48169
22722194
Gamma-aminobutyric acid receptor subunit alpha-5 precursor
P31644
22722194
Gamma-aminobutyric acid receptor subunit alpha-6 precursor
P30191
22722194
InAADR: Drug-Protein-ADRs database