Adverse Drug Reactions(ADRs) are one of the most common cause of death worldwide. Numerous incidents
are reported every year, ADRs affecting community people. ADRs mainly occurs due to the interaction of the drug with
single/multiple proteins present in the body. The consequence is that a given protein target binds many
drugs or their metabolites, and conversely, a drugs or metabolites bind many proteins, all with similar
active sites. These binding causes beneficial and unwanted effects. Similarly, after administration of
the drug in the body, it may bind to the co-administered drug, food or can be converted into toxic
metabolite which causes ADRs. |
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